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P25576

- POF1_YEAST

UniProt

P25576 - POF1_YEAST

Protein

Promoter of filamentation protein 1

Gene

POF1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 May 1992)
      Previous versions | rss
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    Functioni

    Involved in the filamentation pathway. Suppresses the filamentation defect of a KSS1 deletion.1 Publication

    GO - Molecular functioni

    1. ATPase activity Source: SGD
    2. nicotinamide-nucleotide adenylyltransferase activity Source: SGD

    GO - Biological processi

    1. ATP catabolic process Source: GOC
    2. ER-associated ubiquitin-dependent protein catabolic process Source: SGD
    3. invasive growth in response to glucose limitation Source: SGD
    4. NAD biosynthesis via nicotinamide riboside salvage pathway Source: SGD
    5. pseudohyphal growth Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-29302-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Promoter of filamentation protein 1
    Gene namesi
    Name:POF1
    Ordered Locus Names:YCL047C
    ORF Names:YCL47C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome III

    Organism-specific databases

    CYGDiYCL047c.
    SGDiS000000552. POF1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: SGD
    2. nucleus Source: SGD

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 258258Promoter of filamentation protein 1PRO_0000202549Add
    BLAST

    Proteomic databases

    MaxQBiP25576.
    PaxDbiP25576.
    PeptideAtlasiP25576.

    Expressioni

    Gene expression databases

    GenevestigatoriP25576.

    Interactioni

    Subunit structurei

    Interacts with KSS1.1 Publication

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    PRP40P332031EBI-21752,EBI-701
    SSM4P403181EBI-21752,EBI-18208

    Protein-protein interaction databases

    BioGridi30938. 5 interactions.
    IntActiP25576. 3 interactions.
    MINTiMINT-2492497.
    STRINGi4932.YCL047C.

    Structurei

    3D structure databases

    ProteinModelPortaliP25576.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the POF1 family.Curated

    Phylogenomic databases

    eggNOGiNOG77130.
    OMAiGLTNHAK.
    OrthoDBiEOG7BGHZG.

    Family and domain databases

    Gene3Di3.40.50.620. 2 hits.
    InterProiIPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P25576-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKTFEQFRK SNLLFQVLKG PQHLECQKLF VLDSSFNPPH LAHFQLLSQT    50
    IKNFKLKDTR SHVLLLLAVN NADKLPKPAS FPTRLEMMCL FADYLQEKLP 100
    QSVVSVGLTV FSKFIDKDKI LHEQFVKGCS ADIGYLVGFD TIARIFDEKY 150
    YHPLKISDVM ESFMSGSQLY CLARGDCHLS AESQLRYASD ILEGKFEPVI 200
    PREWGARIHV MQNDYPALRN VSSSEIRNKL KNGQVESLKD ELPLCIYDYL 250
    INNKTIFD 258
    Length:258
    Mass (Da):29,673
    Last modified:May 1, 1992 - v1
    Checksum:i1A55281FC19854C7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59720 Genomic DNA. Translation: CAA42369.1.
    BK006937 Genomic DNA. Translation: DAA07439.1.
    PIRiS19376.
    RefSeqiNP_009883.1. NM_001178692.1.

    Genome annotation databases

    EnsemblFungiiYCL047C; YCL047C; YCL047C.
    GeneIDi850310.
    KEGGisce:YCL047C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59720 Genomic DNA. Translation: CAA42369.1 .
    BK006937 Genomic DNA. Translation: DAA07439.1 .
    PIRi S19376.
    RefSeqi NP_009883.1. NM_001178692.1.

    3D structure databases

    ProteinModelPortali P25576.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 30938. 5 interactions.
    IntActi P25576. 3 interactions.
    MINTi MINT-2492497.
    STRINGi 4932.YCL047C.

    Proteomic databases

    MaxQBi P25576.
    PaxDbi P25576.
    PeptideAtlasi P25576.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YCL047C ; YCL047C ; YCL047C .
    GeneIDi 850310.
    KEGGi sce:YCL047C.

    Organism-specific databases

    CYGDi YCL047c.
    SGDi S000000552. POF1.

    Phylogenomic databases

    eggNOGi NOG77130.
    OMAi GLTNHAK.
    OrthoDBi EOG7BGHZG.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-29302-MONOMER.

    Miscellaneous databases

    NextBioi 965706.

    Gene expression databases

    Genevestigatori P25576.

    Family and domain databases

    Gene3Di 3.40.50.620. 2 hits.
    InterProi IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete DNA sequence of yeast chromosome III."
      Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
      , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
      Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    4. "Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes."
      Fasolo J., Sboner A., Sun M.G., Yu H., Chen R., Sharon D., Kim P.M., Gerstein M., Snyder M.
      Genes Dev. 25:767-778(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH KSS1.
    5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiPOF1_YEAST
    AccessioniPrimary (citable) accession number: P25576
    Secondary accession number(s): D6VQX0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: May 1, 1992
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 830 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome III
      Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

    External Data

    Dasty 3