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P25576

- POF1_YEAST

UniProt

P25576 - POF1_YEAST

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Protein

Promoter of filamentation protein 1

Gene
POF1, YCL047C, YCL47C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in the filamentation pathway. Suppresses the filamentation defect of a KSS1 deletion.1 Publication

GO - Molecular functioni

  1. ATPase activity Source: SGD
  2. nicotinamide-nucleotide adenylyltransferase activity Source: SGD

GO - Biological processi

  1. ATP catabolic process Source: GOC
  2. ER-associated ubiquitin-dependent protein catabolic process Source: SGD
  3. invasive growth in response to glucose limitation Source: SGD
  4. NAD biosynthesis via nicotinamide riboside salvage pathway Source: SGD
  5. pseudohyphal growth Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29302-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Promoter of filamentation protein 1
Gene namesi
Name:POF1
Ordered Locus Names:YCL047C
ORF Names:YCL47C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome III

Organism-specific databases

CYGDiYCL047c.
SGDiS000000552. POF1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: SGD
  2. nucleus Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 258258Promoter of filamentation protein 1PRO_0000202549Add
BLAST

Proteomic databases

MaxQBiP25576.
PaxDbiP25576.
PeptideAtlasiP25576.

Expressioni

Gene expression databases

GenevestigatoriP25576.

Interactioni

Subunit structurei

Interacts with KSS1.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
PRP40P332031EBI-21752,EBI-701
SSM4P403181EBI-21752,EBI-18208

Protein-protein interaction databases

BioGridi30938. 5 interactions.
IntActiP25576. 3 interactions.
MINTiMINT-2492497.
STRINGi4932.YCL047C.

Structurei

3D structure databases

ProteinModelPortaliP25576.

Family & Domainsi

Sequence similaritiesi

Belongs to the POF1 family.

Phylogenomic databases

eggNOGiNOG77130.
OMAiGLTNHAK.
OrthoDBiEOG7BGHZG.

Family and domain databases

Gene3Di3.40.50.620. 2 hits.
InterProiIPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P25576-1 [UniParc]FASTAAdd to Basket

« Hide

MKKTFEQFRK SNLLFQVLKG PQHLECQKLF VLDSSFNPPH LAHFQLLSQT    50
IKNFKLKDTR SHVLLLLAVN NADKLPKPAS FPTRLEMMCL FADYLQEKLP 100
QSVVSVGLTV FSKFIDKDKI LHEQFVKGCS ADIGYLVGFD TIARIFDEKY 150
YHPLKISDVM ESFMSGSQLY CLARGDCHLS AESQLRYASD ILEGKFEPVI 200
PREWGARIHV MQNDYPALRN VSSSEIRNKL KNGQVESLKD ELPLCIYDYL 250
INNKTIFD 258
Length:258
Mass (Da):29,673
Last modified:May 1, 1992 - v1
Checksum:i1A55281FC19854C7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X59720 Genomic DNA. Translation: CAA42369.1.
BK006937 Genomic DNA. Translation: DAA07439.1.
PIRiS19376.
RefSeqiNP_009883.1. NM_001178692.1.

Genome annotation databases

EnsemblFungiiYCL047C; YCL047C; YCL047C.
GeneIDi850310.
KEGGisce:YCL047C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X59720 Genomic DNA. Translation: CAA42369.1 .
BK006937 Genomic DNA. Translation: DAA07439.1 .
PIRi S19376.
RefSeqi NP_009883.1. NM_001178692.1.

3D structure databases

ProteinModelPortali P25576.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 30938. 5 interactions.
IntActi P25576. 3 interactions.
MINTi MINT-2492497.
STRINGi 4932.YCL047C.

Proteomic databases

MaxQBi P25576.
PaxDbi P25576.
PeptideAtlasi P25576.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YCL047C ; YCL047C ; YCL047C .
GeneIDi 850310.
KEGGi sce:YCL047C.

Organism-specific databases

CYGDi YCL047c.
SGDi S000000552. POF1.

Phylogenomic databases

eggNOGi NOG77130.
OMAi GLTNHAK.
OrthoDBi EOG7BGHZG.

Enzyme and pathway databases

BioCyci YEAST:G3O-29302-MONOMER.

Miscellaneous databases

NextBioi 965706.

Gene expression databases

Genevestigatori P25576.

Family and domain databases

Gene3Di 3.40.50.620. 2 hits.
InterProi IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The complete DNA sequence of yeast chromosome III."
    Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
    , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
    Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  4. "Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes."
    Fasolo J., Sboner A., Sun M.G., Yu H., Chen R., Sharon D., Kim P.M., Gerstein M., Snyder M.
    Genes Dev. 25:767-778(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH KSS1.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiPOF1_YEAST
AccessioniPrimary (citable) accession number: P25576
Secondary accession number(s): D6VQX0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: September 3, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 830 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

External Data

Dasty 3

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