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Protein

Maf-like protein YhdE

Gene

yhdE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei33 – 331Sequence analysis

GO - Molecular functioni

  • dTTP diphosphatase activity Source: EcoCyc
  • identical protein binding Source: EcoCyc
  • nucleoside-triphosphate diphosphatase activity Source: EcoliWiki
  • UTP diphosphatase activity Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11298-MONOMER.
ECOL316407:JW3217-MONOMER.
MetaCyc:EG11298-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Maf-like protein YhdE
Gene namesi
Name:yhdE
Ordered Locus Names:b3248, JW3217
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11298. yhdE.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 197197Maf-like protein YhdEPRO_0000122981Add
BLAST

Proteomic databases

PaxDbiP25536.
PRIDEiP25536.

Interactioni

GO - Molecular functioni

  • identical protein binding Source: EcoCyc

Protein-protein interaction databases

BioGridi4262448. 147 interactions.
IntActiP25536. 4 interactions.
STRINGi511145.b3248.

Structurei

Secondary structure

1
197
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 63Combined sources
Helixi11 – 199Combined sources
Beta strandi24 – 263Combined sources
Helixi41 – 5818Combined sources
Beta strandi66 – 7510Combined sources
Beta strandi78 – 803Combined sources
Helixi86 – 9611Combined sources
Beta strandi100 – 11011Combined sources
Beta strandi115 – 12612Combined sources
Helixi131 – 1388Combined sources
Helixi142 – 1454Combined sources
Helixi147 – 1493Combined sources
Beta strandi152 – 1543Combined sources
Helixi155 – 1595Combined sources
Beta strandi160 – 1656Combined sources
Helixi167 – 1715Combined sources
Helixi175 – 18814Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4P0EX-ray2.30A/B2-190[»]
ProteinModelPortaliP25536.
SMRiP25536. Positions 2-190.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the maf family.Curated

Phylogenomic databases

eggNOGiENOG4108Z03. Bacteria.
COG0424. LUCA.
HOGENOMiHOG000241745.
InParanoidiP25536.
KOiK06287.
OMAiVITGYCI.
OrthoDBiEOG6SV5F0.
PhylomeDBiP25536.

Family and domain databases

Gene3Di3.90.950.10. 1 hit.
HAMAPiMF_00528. Maf.
InterProiIPR029001. ITPase-like_fam.
IPR003697. Maf.
[Graphical view]
PfamiPF02545. Maf. 1 hit.
[Graphical view]
PIRSFiPIRSF006305. Maf. 1 hit.
SUPFAMiSSF52972. SSF52972. 1 hit.
TIGRFAMsiTIGR00172. maf. 1 hit.

Sequencei

Sequence statusi: Complete.

P25536-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSLYLASGS PRRQELLAQL GVTFERIVTG IEEQRQPQES AQQYVVRLAR
60 70 80 90 100
EKARAGVAQT AKDLPVLGAD TIVILNGEVL EKPRDAEHAA QMLRKLSGQT
110 120 130 140 150
HQVMTAVALA DSQHILDCLV VTDVTFRTLT DEDIAGYVAS DEPLDKAGAY
160 170 180 190
GIQGLGGCFV RKINGSYHAV VGLPLVETYE LLSNFNALRE KRDKHDG
Length:197
Mass (Da):21,515
Last modified:May 1, 1992 - v1
Checksum:iD023A366FB71DA87
GO

Sequence cautioni

The sequence AAA58051.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57166 Genomic DNA. Translation: CAA40456.1.
U18997 Genomic DNA. Translation: AAA58051.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76280.1.
AP009048 Genomic DNA. Translation: BAE77290.1.
PIRiJQ1271.
RefSeqiNP_417714.1. NC_000913.3.
WP_000203105.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76280; AAC76280; b3248.
BAE77290; BAE77290; BAE77290.
GeneIDi947753.
KEGGiecj:JW3217.
eco:b3248.
PATRICi32121922. VBIEscCol129921_3345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57166 Genomic DNA. Translation: CAA40456.1.
U18997 Genomic DNA. Translation: AAA58051.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76280.1.
AP009048 Genomic DNA. Translation: BAE77290.1.
PIRiJQ1271.
RefSeqiNP_417714.1. NC_000913.3.
WP_000203105.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4P0EX-ray2.30A/B2-190[»]
ProteinModelPortaliP25536.
SMRiP25536. Positions 2-190.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262448. 147 interactions.
IntActiP25536. 4 interactions.
STRINGi511145.b3248.

Proteomic databases

PaxDbiP25536.
PRIDEiP25536.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76280; AAC76280; b3248.
BAE77290; BAE77290; BAE77290.
GeneIDi947753.
KEGGiecj:JW3217.
eco:b3248.
PATRICi32121922. VBIEscCol129921_3345.

Organism-specific databases

EchoBASEiEB1275.
EcoGeneiEG11298. yhdE.

Phylogenomic databases

eggNOGiENOG4108Z03. Bacteria.
COG0424. LUCA.
HOGENOMiHOG000241745.
InParanoidiP25536.
KOiK06287.
OMAiVITGYCI.
OrthoDBiEOG6SV5F0.
PhylomeDBiP25536.

Enzyme and pathway databases

BioCyciEcoCyc:EG11298-MONOMER.
ECOL316407:JW3217-MONOMER.
MetaCyc:EG11298-MONOMER.

Miscellaneous databases

PROiP25536.

Family and domain databases

Gene3Di3.90.950.10. 1 hit.
HAMAPiMF_00528. Maf.
InterProiIPR029001. ITPase-like_fam.
IPR003697. Maf.
[Graphical view]
PfamiPF02545. Maf. 1 hit.
[Graphical view]
PIRSFiPIRSF006305. Maf. 1 hit.
SUPFAMiSSF52972. SSF52972. 1 hit.
TIGRFAMsiTIGR00172. maf. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence of the downstream flanking region of the shape-determining genes mreBCD of Escherichia coli."
    Wachi M., Doi M., Ueda T., Ueki M., Tsuritani K., Nagai K., Matsuhashi M.
    Gene 106:135-136(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography."
    Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B.
    Electrophoresis 20:2181-2195(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: B / BL21.

Entry informationi

Entry nameiYHDE_ECOLI
AccessioniPrimary (citable) accession number: P25536
Secondary accession number(s): Q2M8W6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: April 13, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.