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Protein

Maf-like protein YhdE

Gene

yhdE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei33Sequence analysis1

GO - Molecular functioni

  • dTTP diphosphatase activity Source: EcoCyc
  • identical protein binding Source: EcoCyc
  • nucleoside-triphosphate diphosphatase activity Source: EcoliWiki
  • UTP diphosphatase activity Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:EG11298-MONOMER
MetaCyc:EG11298-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Maf-like protein YhdE
Gene namesi
Name:yhdE
Ordered Locus Names:b3248, JW3217
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11298 yhdE

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001229811 – 197Maf-like protein YhdEAdd BLAST197

Proteomic databases

PaxDbiP25536
PRIDEiP25536

Interactioni

GO - Molecular functioni

  • identical protein binding Source: EcoCyc

Protein-protein interaction databases

BioGridi4262448, 147 interactors
IntActiP25536, 4 interactors
STRINGi316385.ECDH10B_3424

Structurei

Secondary structure

1197
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 6Combined sources3
Helixi11 – 19Combined sources9
Beta strandi24 – 26Combined sources3
Helixi41 – 58Combined sources18
Beta strandi66 – 75Combined sources10
Beta strandi78 – 80Combined sources3
Helixi86 – 96Combined sources11
Beta strandi100 – 110Combined sources11
Beta strandi115 – 126Combined sources12
Helixi131 – 138Combined sources8
Helixi142 – 145Combined sources4
Helixi147 – 149Combined sources3
Beta strandi152 – 154Combined sources3
Helixi155 – 159Combined sources5
Beta strandi160 – 165Combined sources6
Helixi167 – 171Combined sources5
Helixi175 – 188Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4P0EX-ray2.30A/B2-190[»]
ProteinModelPortaliP25536
SMRiP25536
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the maf family.Curated

Phylogenomic databases

eggNOGiENOG4108Z03 Bacteria
COG0424 LUCA
HOGENOMiHOG000241745
InParanoidiP25536
KOiK06287
OMAiRIDGDFY
PhylomeDBiP25536

Family and domain databases

CDDicd00555 Maf, 1 hit
Gene3Di3.90.950.10, 1 hit
HAMAPiMF_00528 Maf, 1 hit
InterProiView protein in InterPro
IPR029001 ITPase-like_fam
IPR003697 Maf
PANTHERiPTHR43213 PTHR43213, 1 hit
PfamiView protein in Pfam
PF02545 Maf, 1 hit
PIRSFiPIRSF006305 Maf, 1 hit
SUPFAMiSSF52972 SSF52972, 1 hit
TIGRFAMsiTIGR00172 maf, 1 hit

Sequencei

Sequence statusi: Complete.

P25536-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSLYLASGS PRRQELLAQL GVTFERIVTG IEEQRQPQES AQQYVVRLAR
60 70 80 90 100
EKARAGVAQT AKDLPVLGAD TIVILNGEVL EKPRDAEHAA QMLRKLSGQT
110 120 130 140 150
HQVMTAVALA DSQHILDCLV VTDVTFRTLT DEDIAGYVAS DEPLDKAGAY
160 170 180 190
GIQGLGGCFV RKINGSYHAV VGLPLVETYE LLSNFNALRE KRDKHDG
Length:197
Mass (Da):21,515
Last modified:May 1, 1992 - v1
Checksum:iD023A366FB71DA87
GO

Sequence cautioni

The sequence AAA58051 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57166 Genomic DNA Translation: CAA40456.1
U18997 Genomic DNA Translation: AAA58051.1 Different initiation.
U00096 Genomic DNA Translation: AAC76280.1
AP009048 Genomic DNA Translation: BAE77290.1
PIRiJQ1271
RefSeqiNP_417714.1, NC_000913.3
WP_000203105.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76280; AAC76280; b3248
BAE77290; BAE77290; BAE77290
GeneIDi947753
KEGGiecj:JW3217
eco:b3248
PATRICifig|1411691.4.peg.3481

Similar proteinsi

Entry informationi

Entry nameiYHDE_ECOLI
AccessioniPrimary (citable) accession number: P25536
Secondary accession number(s): Q2M8W6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: March 28, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health