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Protein

Maf-like protein YhdE

Gene

yhdE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei33Sequence analysis1

GO - Molecular functioni

  • dTTP diphosphatase activity Source: EcoCyc
  • identical protein binding Source: EcoCyc
  • nucleoside-triphosphate diphosphatase activity Source: EcoliWiki
  • UTP diphosphatase activity Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11298-MONOMER.
ECOL316407:JW3217-MONOMER.
MetaCyc:EG11298-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Maf-like protein YhdE
Gene namesi
Name:yhdE
Ordered Locus Names:b3248, JW3217
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11298. yhdE.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001229811 – 197Maf-like protein YhdEAdd BLAST197

Proteomic databases

PaxDbiP25536.
PRIDEiP25536.

Interactioni

GO - Molecular functioni

  • identical protein binding Source: EcoCyc

Protein-protein interaction databases

BioGridi4262448. 147 interactors.
IntActiP25536. 4 interactors.
STRINGi511145.b3248.

Structurei

Secondary structure

1197
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 6Combined sources3
Helixi11 – 19Combined sources9
Beta strandi24 – 26Combined sources3
Helixi41 – 58Combined sources18
Beta strandi66 – 75Combined sources10
Beta strandi78 – 80Combined sources3
Helixi86 – 96Combined sources11
Beta strandi100 – 110Combined sources11
Beta strandi115 – 126Combined sources12
Helixi131 – 138Combined sources8
Helixi142 – 145Combined sources4
Helixi147 – 149Combined sources3
Beta strandi152 – 154Combined sources3
Helixi155 – 159Combined sources5
Beta strandi160 – 165Combined sources6
Helixi167 – 171Combined sources5
Helixi175 – 188Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4P0EX-ray2.30A/B2-190[»]
ProteinModelPortaliP25536.
SMRiP25536.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the maf family.Curated

Phylogenomic databases

eggNOGiENOG4108Z03. Bacteria.
COG0424. LUCA.
HOGENOMiHOG000241745.
InParanoidiP25536.
KOiK06287.
OMAiVITGYCI.
PhylomeDBiP25536.

Family and domain databases

CDDicd00555. Maf. 1 hit.
Gene3Di3.90.950.10. 1 hit.
HAMAPiMF_00528. Maf. 1 hit.
InterProiIPR029001. ITPase-like_fam.
IPR003697. Maf.
[Graphical view]
PfamiPF02545. Maf. 1 hit.
[Graphical view]
PIRSFiPIRSF006305. Maf. 1 hit.
SUPFAMiSSF52972. SSF52972. 1 hit.
TIGRFAMsiTIGR00172. maf. 1 hit.

Sequencei

Sequence statusi: Complete.

P25536-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSLYLASGS PRRQELLAQL GVTFERIVTG IEEQRQPQES AQQYVVRLAR
60 70 80 90 100
EKARAGVAQT AKDLPVLGAD TIVILNGEVL EKPRDAEHAA QMLRKLSGQT
110 120 130 140 150
HQVMTAVALA DSQHILDCLV VTDVTFRTLT DEDIAGYVAS DEPLDKAGAY
160 170 180 190
GIQGLGGCFV RKINGSYHAV VGLPLVETYE LLSNFNALRE KRDKHDG
Length:197
Mass (Da):21,515
Last modified:May 1, 1992 - v1
Checksum:iD023A366FB71DA87
GO

Sequence cautioni

The sequence AAA58051 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57166 Genomic DNA. Translation: CAA40456.1.
U18997 Genomic DNA. Translation: AAA58051.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76280.1.
AP009048 Genomic DNA. Translation: BAE77290.1.
PIRiJQ1271.
RefSeqiNP_417714.1. NC_000913.3.
WP_000203105.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76280; AAC76280; b3248.
BAE77290; BAE77290; BAE77290.
GeneIDi947753.
KEGGiecj:JW3217.
eco:b3248.
PATRICi32121922. VBIEscCol129921_3345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57166 Genomic DNA. Translation: CAA40456.1.
U18997 Genomic DNA. Translation: AAA58051.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76280.1.
AP009048 Genomic DNA. Translation: BAE77290.1.
PIRiJQ1271.
RefSeqiNP_417714.1. NC_000913.3.
WP_000203105.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4P0EX-ray2.30A/B2-190[»]
ProteinModelPortaliP25536.
SMRiP25536.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262448. 147 interactors.
IntActiP25536. 4 interactors.
STRINGi511145.b3248.

Proteomic databases

PaxDbiP25536.
PRIDEiP25536.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76280; AAC76280; b3248.
BAE77290; BAE77290; BAE77290.
GeneIDi947753.
KEGGiecj:JW3217.
eco:b3248.
PATRICi32121922. VBIEscCol129921_3345.

Organism-specific databases

EchoBASEiEB1275.
EcoGeneiEG11298. yhdE.

Phylogenomic databases

eggNOGiENOG4108Z03. Bacteria.
COG0424. LUCA.
HOGENOMiHOG000241745.
InParanoidiP25536.
KOiK06287.
OMAiVITGYCI.
PhylomeDBiP25536.

Enzyme and pathway databases

BioCyciEcoCyc:EG11298-MONOMER.
ECOL316407:JW3217-MONOMER.
MetaCyc:EG11298-MONOMER.

Miscellaneous databases

PROiP25536.

Family and domain databases

CDDicd00555. Maf. 1 hit.
Gene3Di3.90.950.10. 1 hit.
HAMAPiMF_00528. Maf. 1 hit.
InterProiIPR029001. ITPase-like_fam.
IPR003697. Maf.
[Graphical view]
PfamiPF02545. Maf. 1 hit.
[Graphical view]
PIRSFiPIRSF006305. Maf. 1 hit.
SUPFAMiSSF52972. SSF52972. 1 hit.
TIGRFAMsiTIGR00172. maf. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYHDE_ECOLI
AccessioniPrimary (citable) accession number: P25536
Secondary accession number(s): Q2M8W6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: November 2, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.