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Protein

Glutamine synthetase, chloroplastic

Gene

GLN2

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

The light-modulated chloroplast enzyme, encoded by a nuclear gene and expressed primarily in leaves, is responsible for the reassimilation of the ammonia generated by photorespiration.

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi6.3.1.2 6752

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase, chloroplastic (EC:6.3.1.2)
Alternative name(s):
GS2
Glutamate--ammonia ligase
Gene namesi
Name:GLN2
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Organism-specific databases

MaizeGDBi61728

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL2285357

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 51ChloroplastSequence analysisAdd BLAST51
ChainiPRO_000001117952 – 423Glutamine synthetase, chloroplasticAdd BLAST372

Proteomic databases

PaxDbiP25462
PRIDEiP25462

Expressioni

Gene expression databases

ExpressionAtlasiP25462 differential

Interactioni

Subunit structurei

Homooctamer.

Protein-protein interaction databases

STRINGi4577.GRMZM2G098290_P01

Structurei

3D structure databases

ProteinModelPortaliP25462
SMRiP25462
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG0683 Eukaryota
COG0174 LUCA
HOGENOMiHOG000061500
KOiK01915

Family and domain databases

Gene3Di3.10.20.70, 1 hit
InterProiView protein in InterPro
IPR008147 Gln_synt_b-grasp
IPR036651 Gln_synt_N
IPR014746 Gln_synth/guanido_kin_cat_dom
IPR008146 Gln_synth_cat_dom
IPR027303 Gln_synth_gly_rich_site
IPR027302 Gln_synth_N_conserv_site
PfamiView protein in Pfam
PF00120 Gln-synt_C, 1 hit
PF03951 Gln-synt_N, 1 hit
SMARTiView protein in SMART
SM01230 Gln-synt_C, 1 hit
SUPFAMiSSF54368 SSF54368, 1 hit
SSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00180 GLNA_1, 1 hit
PS00181 GLNA_ATP, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P25462-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQAVVPAMQ CRVGVKAAAG RVWSAGRTRT GRGGASPGFK VMAVSTGSTG
60 70 80 90 100
VVPRLEQLLN MDTTPYTDKV IAEYIWVGGS GIDIRSKSRT ISKPVEDPSE
110 120 130 140 150
LPKWNYDGSS TGQAPGEDSE VILYPQAIFK DPFRGGNNVL VICDTYTPQG
160 170 180 190 200
EPLPTNKRHR AAQIFSDPKV GEQVPWFGIE QEYTLLQKDV NWPLGWPVGG
210 220 230 240 250
FPGPQGPYYC AVGADKSFGR DISDAHYKAC LYAGINISGT NGEVMPGQWE
260 270 280 290 300
YQVGPSVGIE AGDHIWISRY ILERITEQAG VVLTLDPKPI QGDWNGAGCH
310 320 330 340 350
TNYSTKTMRE DGGFEEIKRA ILNLSLRHDL HISAYGEGNE RRLTGKHETA
360 370 380 390 400
SIGTFSWGVA NRGCSIRVGR DTEAKGKGYL EDRRPASNMD PYIVTGLLAE
410 420
TTILWQPSLE AEALAAKKLA LKV
Length:423
Mass (Da):46,017
Last modified:May 1, 1992 - v1
Checksum:iEC799D71E0BD6C5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X65931 mRNA Translation: CAA46724.1
PIRiS39482
RefSeqiNP_001105725.1, NM_001112255.1
UniGeneiZm.160909
Zm.3369

Genome annotation databases

GeneIDi542746
KEGGizma:542746

Similar proteinsi

Entry informationi

Entry nameiGLNAC_MAIZE
AccessioniPrimary (citable) accession number: P25462
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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