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Protein

POU domain, class 2, transcription factor 1

Gene

Pou2f1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi382 – 44160HomeoboxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. chromatin binding Source: MGI
  2. DNA binding Source: MGI
  3. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl
  4. sequence-specific DNA binding Source: MGI

GO - Biological processi

  1. lens induction in camera-type eye Source: MGI
  2. negative regulation of transcription, DNA-templated Source: MGI
  3. olfactory placode formation Source: MGI
  4. positive regulation of transcription from RNA polymerase II promoter Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

ReactomeiREACT_240508. RNA Polymerase III Transcription Initiation From Type 3 Promoter.
REACT_261233. RNA Polymerase III Abortive And Retractive Initiation.

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain, class 2, transcription factor 1
Alternative name(s):
NF-A1
Octamer-binding protein 1
Short name:
Oct-1
Octamer-binding transcription factor 1
Short name:
OTF-1
Gene namesi
Name:Pou2f1
Synonyms:Oct-1, Otf-1, Otf1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 1

Organism-specific databases

MGIiMGI:101898. Pou2f1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. intracellular membrane-bounded organelle Source: MGI
  3. nucleoplasm Source: MGI
  4. nucleus Source: MGI
  5. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 770770POU domain, class 2, transcription factor 1PRO_0000100708Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei271 – 2711PhosphothreonineBy similarity
Modified residuei284 – 2841PhosphoserineBy similarity
Modified residuei388 – 3881PhosphoserineBy similarity
Modified residuei451 – 4511PhosphoserineBy similarity

Post-translational modificationi

Phosphorylated by PRKDC.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP25425.
PaxDbiP25425.
PRIDEiP25425.

PTM databases

PhosphoSiteiP25425.

Expressioni

Tissue specificityi

Ubiquitously expressed. However, isoforms 4 and 5 are only expressed in lymphocytes.4 Publications

Gene expression databases

BgeeiP25425.
CleanExiMM_POU2F1.
ExpressionAtlasiP25425. baseline and differential.
GenevestigatoriP25425.

Interactioni

Subunit structurei

Interacts with NR3C1, AR, PGR and HCFC1.By similarity

Protein-protein interaction databases

BioGridi202301. 16 interactions.

Structurei

3D structure databases

ProteinModelPortaliP25425.
SMRiP25425. Positions 283-441.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini281 – 35575POU-specificPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation
Contains 1 POU-specific domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiNOG267922.
GeneTreeiENSGT00760000118935.
HOVERGENiHBG057016.
InParanoidiP25425.
KOiK09364.
OrthoDBiEOG7DJSMG.
PhylomeDBiP25425.
TreeFamiTF316413.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequences (12)i

Sequence statusi: Complete.

This entry describes 12 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P25425-1) [UniParc]FASTAAdd to basket

Also known as: OCT-1A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNNPSETNKS SMESEDASTG TQTNGLDFQK QPVPVGGAIS TAQAQAFLGH
60 70 80 90 100
LHQVQLAGTS LQAAAQSLNV QSKSSEESGD SQQSSQPSSQ PPSVQSAIPQ
110 120 130 140 150
TQLMLAGGQI TGLTLTPAQQ QLLLQQAQAQ AQLLAAAVQQ HSASQQHSAA
160 170 180 190 200
GATISASAAT PMTQIPLSQP IQIAQDLQQL QQLQQQNLNL QQFVLVHPTT
210 220 230 240 250
NLQPAQFIIS QTPQGQQGLL QAQNLLTQLP QQSQANLLQP QPSITLTSQP
260 270 280 290 300
TTPTRTIAAA SVQTLPQSQS TPKRIDTPSL EEPSDLEELE QFAKTFKQRR
310 320 330 340 350
IKLGFTQGDV GLAMGKLYGN DFSQTTISRF EALNLSFKNM CKLKPLLEKW
360 370 380 390 400
LNDAENLSSD STASSPSALN SPGLGAEGLN RRRKKRTSIE TNIRVALEKS
410 420 430 440 450
FMENQKPTSE DITLIAEQLN MEKEVIRVWF CNRRQKEKRI NPPSSGGTSS
460 470 480 490 500
SPIKAIFPSP ASLVATTPSL VTSSTATTLT VNPVLPLTSA AVTNLSLTDQ
510 520 530 540 550
DLRRGCSWEV LRSLPDRVTT TAGTTDSTSN NNTATVISTA PPASSAVTSP
560 570 580 590 600
SLSPSPSASA STSEASSASE TNTTQTTSTP LPSPLGASQV MVTTPGLQTA
610 620 630 640 650
AAALQGAAQL PANASLAAMA AAAGLSPGLM APSQFAAGGA LLSLSPGTLG
660 670 680 690 700
SALSPALMSN STLATIQALA SSGSLPITSL DATGNLVFAN AGGAPNIVTA
710 720 730 740 750
PLFLNPQNLS LLTSNPVSLV SAAAASTGNS APTASLHASS TSTESIQSSL
760 770
FTVASASGPA STTTAASKAQ
Length:770
Mass (Da):79,547
Last modified:April 23, 2003 - v3
Checksum:iB45CDBE632853FE9
GO
Isoform 2 (identifier: P25425-2) [UniParc]FASTAAdd to basket

Also known as: OCT-1B

The sequence of this isoform differs from the canonical sequence as follows:
     499-522: Missing.

Show »
Length:746
Mass (Da):76,790
Checksum:iA19E2D4CB6C147A2
GO
Isoform 3 (identifier: P25425-3) [UniParc]FASTAAdd to basket

Also known as: OCT-1C

The sequence of this isoform differs from the canonical sequence as follows:
     499-522: Missing.
     717-725: VSLVSAAAA → DCFMDWRTF
     726-770: Missing.

Show »
Length:701
Mass (Da):72,983
Checksum:i85CEC91D2241D0D9
GO
Isoform 4 (identifier: P25425-4) [UniParc]FASTAAdd to basket

Also known as: OCT-1R

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLDCSDCVLDSRM
     54-71: Missing.
     499-522: Missing.
     639-770: Missing.

Show »
Length:608
Mass (Da):63,780
Checksum:iED52028C67A99D5C
GO
Isoform 5 (identifier: P25425-5) [UniParc]FASTAAdd to basket

Also known as: OCT-1L

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLDCSDCVLDSRM
     499-522: Missing.

Show »
Length:758
Mass (Da):78,128
Checksum:iEF08D83A224B2418
GO
Isoform 6 (identifier: P25425-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     668-691: Missing.

Show »
Length:746
Mass (Da):77,274
Checksum:iAEBEE16A471595D4
GO
Isoform 7 (identifier: P25425-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     639-641: GAL → SCF
     642-770: Missing.

Show »
Length:641
Mass (Da):67,317
Checksum:iBD83AEBFA5C51643
GO
Isoform 8 (identifier: P25425-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     668-691: Missing.
     717-725: VSLVSAAAA → DCFMDWRTF
     726-770: Missing.

Show »
Length:701
Mass (Da):73,467
Checksum:iF1092FC5322C5061
GO
Isoform 9 (identifier: P25425-9) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     639-647: GALLSLSPG → IASWIGELS
     648-770: Missing.

Show »
Length:647
Mass (Da):67,937
Checksum:iD59952DB1E8D61F0
GO
Isoform 10 (identifier: P25425-10) [UniParc]FASTAAdd to basket

Also known as: OCT-1Z

The sequence of this isoform differs from the canonical sequence as follows:
     499-522: DQDLRRGCSWEVLRSLPDRVTTTA → GKQQPAYRLVSTVPVRFLWRTARS
     523-770: Missing.

Show »
Length:522
Mass (Da):56,193
Checksum:i6ABAAA323C1F873B
GO
Isoform 11 (identifier: P25425-11) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLDCSDCVLDSRM
     639-770: Missing.

Show »
Length:650
Mass (Da):68,318
Checksum:i649DDF3D7105D736
GO
Isoform 12 (identifier: P25425-12) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MADGGAASQDESSAAAAAAADSR

Note: No experimental confirmation available.

Show »
Length:792
Mass (Da):81,479
Checksum:i96B1978640108D06
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti43 – 431Q → L in CAA39679 (PubMed:1561098).Curated
Sequence conflicti70 – 701V → I in CAC34943 (PubMed:11683265).Curated
Sequence conflicti129 – 1291A → P (PubMed:7711063).Curated
Sequence conflicti168 – 1681S → C in CAD35743 (Ref. 6) Curated
Sequence conflicti188 – 1881L → H in CAC34943 (PubMed:11683265).Curated
Sequence conflicti234 – 2341Q → R in CAC34943 (PubMed:11683265).Curated
Sequence conflicti333 – 3331L → W (PubMed:8376772).Curated
Sequence conflicti360 – 3601D → G in CAC34943 (PubMed:11683265).Curated
Sequence conflicti368 – 3681A → D (PubMed:1970171).Curated
Sequence conflicti441 – 4411N → D in CAC34943 (PubMed:11683265).Curated
Sequence conflicti474 – 4741S → G in CAC34943 (PubMed:11683265).Curated
Sequence conflicti596 – 5961G → D in CAC34943 (PubMed:11683265).Curated
Sequence conflicti608 – 6081A → G in CAA48422 (PubMed:8441632).Curated
Sequence conflicti608 – 6081A → G in CAA48423 (PubMed:8441632).Curated
Sequence conflicti608 – 6081A → G in CAA48424 (PubMed:8441632).Curated
Sequence conflicti609 – 6091Q → R in CAC34943 (PubMed:11683265).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 11M → MADGGAASQDESSAAAAAAA DSR in isoform 12. 1 PublicationVSP_013403
Alternative sequencei1 – 11M → MLDCSDCVLDSRM in isoform 4, isoform 5 and isoform 11. 3 PublicationsVSP_007271
Alternative sequencei54 – 7118Missing in isoform 4. 1 PublicationVSP_007272Add
BLAST
Alternative sequencei499 – 52224DQDLR…VTTTA → GKQQPAYRLVSTVPVRFLWR TARS in isoform 10. 1 PublicationVSP_013404Add
BLAST
Alternative sequencei499 – 52224Missing in isoform 2, isoform 3, isoform 4 and isoform 5. 5 PublicationsVSP_002321Add
BLAST
Alternative sequencei523 – 770248Missing in isoform 10. 1 PublicationVSP_013405Add
BLAST
Alternative sequencei639 – 770132Missing in isoform 4 and isoform 11. 2 PublicationsVSP_007273Add
BLAST
Alternative sequencei639 – 6479GALLSLSPG → IASWIGELS in isoform 9. 1 PublicationVSP_007274
Alternative sequencei639 – 6413GAL → SCF in isoform 7. 1 PublicationVSP_007276
Alternative sequencei642 – 770129Missing in isoform 7. 1 PublicationVSP_007277Add
BLAST
Alternative sequencei648 – 770123Missing in isoform 9. 1 PublicationVSP_007275Add
BLAST
Alternative sequencei668 – 69124Missing in isoform 6 and isoform 8. 2 PublicationsVSP_007278Add
BLAST
Alternative sequencei717 – 7259VSLVSAAAA → DCFMDWRTF in isoform 3 and isoform 8. 2 PublicationsVSP_002322
Alternative sequencei726 – 77045Missing in isoform 3 and isoform 8. 2 PublicationsVSP_002323Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68362 mRNA. Translation: CAA48422.1.
X68363 mRNA. Translation: CAA48423.1.
X68364 mRNA. Translation: CAA48424.1.
X56230 mRNA. Translation: CAA39679.1.
AJ296212 mRNA. Translation: CAC34943.1.
AF508939 mRNA. Translation: AAM34281.1.
AY177625 mRNA. Translation: AAO45298.1.
AJ489474 mRNA. Translation: CAD35743.1.
AK028237 mRNA. Translation: BAC25832.1.
S65461 mRNA. Translation: AAB28234.1.
X70324 mRNA. Translation: CAA49791.1.
X70325 mRNA. Translation: CAA49792.1.
X51958 mRNA. Translation: CAA36217.1.
AF095458 mRNA. Translation: AAD25325.1.
AF095459 mRNA. Translation: AAD25326.1.
AF095460 mRNA. Translation: AAD25327.1.
CCDSiCCDS15444.1. [P25425-5]
PIRiI56187.
S30293.
RefSeqiNP_035267.2. NM_011137.3.
NP_945151.2. NM_198933.3. [P25425-5]
XP_006496767.1. XM_006496704.1. [P25425-1]
XP_006496768.1. XM_006496705.1. [P25425-1]
XP_006496769.1. XM_006496706.1. [P25425-1]
UniGeneiMm.245261.

Genome annotation databases

EnsembliENSMUST00000069609; ENSMUSP00000064000; ENSMUSG00000026565. [P25425-5]
ENSMUST00000111429; ENSMUSP00000107057; ENSMUSG00000026565. [P25425-2]
ENSMUST00000184643; ENSMUSP00000138962; ENSMUSG00000026565. [P25425-3]
GeneIDi18986.
KEGGimmu:18986.
UCSCiuc007djv.1. mouse. [P25425-6]
uc007djx.2. mouse. [P25425-5]
uc007dkb.2. mouse. [P25425-4]
uc007dkc.2. mouse. [P25425-11]
uc007dke.1. mouse. [P25425-10]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68362 mRNA. Translation: CAA48422.1.
X68363 mRNA. Translation: CAA48423.1.
X68364 mRNA. Translation: CAA48424.1.
X56230 mRNA. Translation: CAA39679.1.
AJ296212 mRNA. Translation: CAC34943.1.
AF508939 mRNA. Translation: AAM34281.1.
AY177625 mRNA. Translation: AAO45298.1.
AJ489474 mRNA. Translation: CAD35743.1.
AK028237 mRNA. Translation: BAC25832.1.
S65461 mRNA. Translation: AAB28234.1.
X70324 mRNA. Translation: CAA49791.1.
X70325 mRNA. Translation: CAA49792.1.
X51958 mRNA. Translation: CAA36217.1.
AF095458 mRNA. Translation: AAD25325.1.
AF095459 mRNA. Translation: AAD25326.1.
AF095460 mRNA. Translation: AAD25327.1.
CCDSiCCDS15444.1. [P25425-5]
PIRiI56187.
S30293.
RefSeqiNP_035267.2. NM_011137.3.
NP_945151.2. NM_198933.3. [P25425-5]
XP_006496767.1. XM_006496704.1. [P25425-1]
XP_006496768.1. XM_006496705.1. [P25425-1]
XP_006496769.1. XM_006496706.1. [P25425-1]
UniGeneiMm.245261.

3D structure databases

ProteinModelPortaliP25425.
SMRiP25425. Positions 283-441.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi202301. 16 interactions.

PTM databases

PhosphoSiteiP25425.

Proteomic databases

MaxQBiP25425.
PaxDbiP25425.
PRIDEiP25425.

Protocols and materials databases

DNASUi18986.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000069609; ENSMUSP00000064000; ENSMUSG00000026565. [P25425-5]
ENSMUST00000111429; ENSMUSP00000107057; ENSMUSG00000026565. [P25425-2]
ENSMUST00000184643; ENSMUSP00000138962; ENSMUSG00000026565. [P25425-3]
GeneIDi18986.
KEGGimmu:18986.
UCSCiuc007djv.1. mouse. [P25425-6]
uc007djx.2. mouse. [P25425-5]
uc007dkb.2. mouse. [P25425-4]
uc007dkc.2. mouse. [P25425-11]
uc007dke.1. mouse. [P25425-10]

Organism-specific databases

CTDi5451.
MGIiMGI:101898. Pou2f1.

Phylogenomic databases

eggNOGiNOG267922.
GeneTreeiENSGT00760000118935.
HOVERGENiHBG057016.
InParanoidiP25425.
KOiK09364.
OrthoDBiEOG7DJSMG.
PhylomeDBiP25425.
TreeFamiTF316413.

Enzyme and pathway databases

ReactomeiREACT_240508. RNA Polymerase III Transcription Initiation From Type 3 Promoter.
REACT_261233. RNA Polymerase III Abortive And Retractive Initiation.

Miscellaneous databases

ChiTaRSiPou2f1. mouse.
NextBioi295362.
PROiP25425.
SOURCEiSearch...

Gene expression databases

BgeeiP25425.
CleanExiMM_POU2F1.
ExpressionAtlasiP25425. baseline and differential.
GenevestigatoriP25425.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Mouse Oct-1 contains a composite homeodomain of human Oct-1 and Oct-2."
    Suzuki N., Peter W., Ciesiolka T., Gruss P., Schoeler H.R.
    Nucleic Acids Res. 21:245-252(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3).
  2. "The nucleotide sequence of mouse OCT-1 cDNA."
    Stepchenko A.G.
    Nucleic Acids Res. 20:1419-1419(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4).
  3. "Tissue-specific isoforms of the ubiquitous transcription factor Oct-1."
    Pankratova E.V., Deyev I.E., Zhenilo S.V., Polanovsky O.L.
    Mol. Genet. Genomics 266:239-245(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5), TISSUE SPECIFICITY.
  4. "Involvement of Oct-1 in transcriptional regulation of beta-casein gene expression in mouse mammary gland."
    Zhao F.-Q., Adachi K., Oka T.
    Biochim. Biophys. Acta 1577:27-37(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    Strain: C3H/HeN.
    Tissue: Mammary gland.
  5. "Cloning, genomic organization, expression, and effect on beta-casein promoter activity of a novel isoform of the mouse Oct-1 transcription factor."
    Zhao F.-Q., Zheng Y., Dong B., Oka T.
    Gene 326:175-187(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 10), TISSUE SPECIFICITY.
    Tissue: Lung.
  6. "Novel isoforms of mRNA of gene oct-1."
    Deyev I.E., Zhenilo S.V., Pankratova E.V., Polanovsky O.L.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 11).
    Strain: BALB/c.
    Tissue: Myeloma.
  7. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 12).
    Strain: C57BL/6J.
    Tissue: Embryo.
  8. "CD3 zeta/eta/theta locus is colinear with and transcribed antisense to the gene encoding the transcription factor Oct-1."
    Lerner A., D'Adamio L., Diener A.C., Clayton L.K., Reinherz E.L.
    J. Immunol. 151:3152-3162(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-770.
  9. "Cloning, sequencing and expression of two isoforms of the murine oct-1 transcription factor."
    Jaffe J., Hochberg M., Riss J., Hasin T., Reich L., Laskov R.
    Biochim. Biophys. Acta 1261:201-209(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 30-770 (ISOFORMS 2 AND 6), TISSUE SPECIFICITY.
    Strain: C57BL/6 X DBA/20.
    Tissue: Lymphoid tissue.
  10. "Cloning and sequencing of POU-boxes expressed in mouse testis."
    Goldsborough A., Ashworth A., Willison K.R.
    Nucleic Acids Res. 18:1634-1634(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 305-426.
    Tissue: Testis.
  11. "Expression of novel alternatively spliced isoforms of the oct-1 transcription factor."
    Riss J., Laskov R.
    Biochim. Biophys. Acta 1444:295-298(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 669-770 (ISOFORMS 7; 8 AND 9), TISSUE SPECIFICITY.
    Strain: BALB/c.
    Tissue: Testis.

Entry informationi

Entry nameiPO2F1_MOUSE
AccessioniPrimary (citable) accession number: P25425
Secondary accession number(s): Q61994
, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: April 23, 2003
Last modified: March 4, 2015
This is version 152 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.