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P25425

- PO2F1_MOUSE

UniProt

P25425 - PO2F1_MOUSE

Protein

POU domain, class 2, transcription factor 1

Gene

Pou2f1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
    • BLAST
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    • History
      Entry version 147 (01 Oct 2014)
      Sequence version 3 (23 Apr 2003)
      Previous versions | rss
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    Functioni

    Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi382 – 44160HomeoboxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. protein binding Source: MGI
    3. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl
    4. sequence-specific DNA binding Source: MGI

    GO - Biological processi

    1. lens induction in camera-type eye Source: MGI
    2. negative regulation of transcription, DNA-templated Source: MGI
    3. olfactory placode formation Source: MGI
    4. positive regulation of transcription from RNA polymerase II promoter Source: MGI

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    POU domain, class 2, transcription factor 1
    Alternative name(s):
    NF-A1
    Octamer-binding protein 1
    Short name:
    Oct-1
    Octamer-binding transcription factor 1
    Short name:
    OTF-1
    Gene namesi
    Name:Pou2f1
    Synonyms:Oct-1, Otf-1, Otf1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 1

    Organism-specific databases

    MGIiMGI:101898. Pou2f1.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: MGI
    2. transcription factor complex Source: MGI

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 770770POU domain, class 2, transcription factor 1PRO_0000100708Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei271 – 2711PhosphothreonineBy similarity
    Modified residuei284 – 2841PhosphoserineBy similarity
    Modified residuei388 – 3881PhosphoserineBy similarity
    Modified residuei451 – 4511PhosphoserineBy similarity

    Post-translational modificationi

    Phosphorylated by PRKDC.By similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiP25425.
    PRIDEiP25425.

    PTM databases

    PhosphoSiteiP25425.

    Expressioni

    Tissue specificityi

    Ubiquitously expressed. However, isoforms 4 and 5 are only expressed in lymphocytes.4 Publications

    Gene expression databases

    ArrayExpressiP25425.
    BgeeiP25425.
    CleanExiMM_POU2F1.
    GenevestigatoriP25425.

    Interactioni

    Subunit structurei

    Interacts with NR3C1, AR, PGR and HCFC1.By similarity

    Protein-protein interaction databases

    BioGridi202301. 13 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliP25425.
    SMRiP25425. Positions 283-441.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini281 – 35575POU-specificPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation
    Contains 1 POU-specific domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Homeobox

    Phylogenomic databases

    eggNOGiNOG267922.
    GeneTreeiENSGT00750000117373.
    HOVERGENiHBG057016.
    InParanoidiP25425.
    KOiK09364.
    OrthoDBiEOG7DJSMG.
    PhylomeDBiP25425.
    TreeFamiTF316413.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR000327. POU_specific.
    IPR000972. TF_octamer.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view]
    PRINTSiPR00029. OCTAMER.
    PR00028. POUDOMAIN.
    SMARTiSM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view]

    Sequences (12)i

    Sequence statusi: Complete.

    This entry describes 12 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P25425-1) [UniParc]FASTAAdd to Basket

    Also known as: OCT-1A

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MNNPSETNKS SMESEDASTG TQTNGLDFQK QPVPVGGAIS TAQAQAFLGH    50
    LHQVQLAGTS LQAAAQSLNV QSKSSEESGD SQQSSQPSSQ PPSVQSAIPQ 100
    TQLMLAGGQI TGLTLTPAQQ QLLLQQAQAQ AQLLAAAVQQ HSASQQHSAA 150
    GATISASAAT PMTQIPLSQP IQIAQDLQQL QQLQQQNLNL QQFVLVHPTT 200
    NLQPAQFIIS QTPQGQQGLL QAQNLLTQLP QQSQANLLQP QPSITLTSQP 250
    TTPTRTIAAA SVQTLPQSQS TPKRIDTPSL EEPSDLEELE QFAKTFKQRR 300
    IKLGFTQGDV GLAMGKLYGN DFSQTTISRF EALNLSFKNM CKLKPLLEKW 350
    LNDAENLSSD STASSPSALN SPGLGAEGLN RRRKKRTSIE TNIRVALEKS 400
    FMENQKPTSE DITLIAEQLN MEKEVIRVWF CNRRQKEKRI NPPSSGGTSS 450
    SPIKAIFPSP ASLVATTPSL VTSSTATTLT VNPVLPLTSA AVTNLSLTDQ 500
    DLRRGCSWEV LRSLPDRVTT TAGTTDSTSN NNTATVISTA PPASSAVTSP 550
    SLSPSPSASA STSEASSASE TNTTQTTSTP LPSPLGASQV MVTTPGLQTA 600
    AAALQGAAQL PANASLAAMA AAAGLSPGLM APSQFAAGGA LLSLSPGTLG 650
    SALSPALMSN STLATIQALA SSGSLPITSL DATGNLVFAN AGGAPNIVTA 700
    PLFLNPQNLS LLTSNPVSLV SAAAASTGNS APTASLHASS TSTESIQSSL 750
    FTVASASGPA STTTAASKAQ 770
    Length:770
    Mass (Da):79,547
    Last modified:April 23, 2003 - v3
    Checksum:iB45CDBE632853FE9
    GO
    Isoform 2 (identifier: P25425-2) [UniParc]FASTAAdd to Basket

    Also known as: OCT-1B

    The sequence of this isoform differs from the canonical sequence as follows:
         499-522: Missing.

    Show »
    Length:746
    Mass (Da):76,790
    Checksum:iA19E2D4CB6C147A2
    GO
    Isoform 3 (identifier: P25425-3) [UniParc]FASTAAdd to Basket

    Also known as: OCT-1C

    The sequence of this isoform differs from the canonical sequence as follows:
         499-522: Missing.
         717-725: VSLVSAAAA → DCFMDWRTF
         726-770: Missing.

    Show »
    Length:701
    Mass (Da):72,983
    Checksum:i85CEC91D2241D0D9
    GO
    Isoform 4 (identifier: P25425-4) [UniParc]FASTAAdd to Basket

    Also known as: OCT-1R

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1: M → MLDCSDCVLDSRM
         54-71: Missing.
         499-522: Missing.
         639-770: Missing.

    Show »
    Length:608
    Mass (Da):63,780
    Checksum:iED52028C67A99D5C
    GO
    Isoform 5 (identifier: P25425-5) [UniParc]FASTAAdd to Basket

    Also known as: OCT-1L

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1: M → MLDCSDCVLDSRM
         499-522: Missing.

    Show »
    Length:758
    Mass (Da):78,128
    Checksum:iEF08D83A224B2418
    GO
    Isoform 6 (identifier: P25425-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         668-691: Missing.

    Show »
    Length:746
    Mass (Da):77,274
    Checksum:iAEBEE16A471595D4
    GO
    Isoform 7 (identifier: P25425-7) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         639-641: GAL → SCF
         642-770: Missing.

    Show »
    Length:641
    Mass (Da):67,317
    Checksum:iBD83AEBFA5C51643
    GO
    Isoform 8 (identifier: P25425-8) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         668-691: Missing.
         717-725: VSLVSAAAA → DCFMDWRTF
         726-770: Missing.

    Show »
    Length:701
    Mass (Da):73,467
    Checksum:iF1092FC5322C5061
    GO
    Isoform 9 (identifier: P25425-9) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         639-647: GALLSLSPG → IASWIGELS
         648-770: Missing.

    Show »
    Length:647
    Mass (Da):67,937
    Checksum:iD59952DB1E8D61F0
    GO
    Isoform 10 (identifier: P25425-10) [UniParc]FASTAAdd to Basket

    Also known as: OCT-1Z

    The sequence of this isoform differs from the canonical sequence as follows:
         499-522: DQDLRRGCSWEVLRSLPDRVTTTA → GKQQPAYRLVSTVPVRFLWRTARS
         523-770: Missing.

    Show »
    Length:522
    Mass (Da):56,193
    Checksum:i6ABAAA323C1F873B
    GO
    Isoform 11 (identifier: P25425-11) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1: M → MLDCSDCVLDSRM
         639-770: Missing.

    Show »
    Length:650
    Mass (Da):68,318
    Checksum:i649DDF3D7105D736
    GO
    Isoform 12 (identifier: P25425-12) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1: M → MADGGAASQDESSAAAAAAADSR

    Note: No experimental confirmation available.

    Show »
    Length:792
    Mass (Da):81,479
    Checksum:i96B1978640108D06
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti43 – 431Q → L in CAA39679. (PubMed:1561098)Curated
    Sequence conflicti70 – 701V → I in CAC34943. (PubMed:11683265)Curated
    Sequence conflicti129 – 1291A → P(PubMed:7711063)Curated
    Sequence conflicti168 – 1681S → C in CAD35743. 1 PublicationCurated
    Sequence conflicti188 – 1881L → H in CAC34943. (PubMed:11683265)Curated
    Sequence conflicti234 – 2341Q → R in CAC34943. (PubMed:11683265)Curated
    Sequence conflicti333 – 3331L → W(PubMed:8376772)Curated
    Sequence conflicti360 – 3601D → G in CAC34943. (PubMed:11683265)Curated
    Sequence conflicti368 – 3681A → D(PubMed:1970171)Curated
    Sequence conflicti441 – 4411N → D in CAC34943. (PubMed:11683265)Curated
    Sequence conflicti474 – 4741S → G in CAC34943. (PubMed:11683265)Curated
    Sequence conflicti596 – 5961G → D in CAC34943. (PubMed:11683265)Curated
    Sequence conflicti608 – 6081A → G in CAA48422. (PubMed:8441632)Curated
    Sequence conflicti608 – 6081A → G in CAA48423. (PubMed:8441632)Curated
    Sequence conflicti608 – 6081A → G in CAA48424. (PubMed:8441632)Curated
    Sequence conflicti609 – 6091Q → R in CAC34943. (PubMed:11683265)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 11M → MADGGAASQDESSAAAAAAA DSR in isoform 12. 1 PublicationVSP_013403
    Alternative sequencei1 – 11M → MLDCSDCVLDSRM in isoform 4, isoform 5 and isoform 11. 3 PublicationsVSP_007271
    Alternative sequencei54 – 7118Missing in isoform 4. 1 PublicationVSP_007272Add
    BLAST
    Alternative sequencei499 – 52224DQDLR…VTTTA → GKQQPAYRLVSTVPVRFLWR TARS in isoform 10. 1 PublicationVSP_013404Add
    BLAST
    Alternative sequencei499 – 52224Missing in isoform 2, isoform 3, isoform 4 and isoform 5. 5 PublicationsVSP_002321Add
    BLAST
    Alternative sequencei523 – 770248Missing in isoform 10. 1 PublicationVSP_013405Add
    BLAST
    Alternative sequencei639 – 770132Missing in isoform 4 and isoform 11. 2 PublicationsVSP_007273Add
    BLAST
    Alternative sequencei639 – 6479GALLSLSPG → IASWIGELS in isoform 9. 1 PublicationVSP_007274
    Alternative sequencei639 – 6413GAL → SCF in isoform 7. 1 PublicationVSP_007276
    Alternative sequencei642 – 770129Missing in isoform 7. 1 PublicationVSP_007277Add
    BLAST
    Alternative sequencei648 – 770123Missing in isoform 9. 1 PublicationVSP_007275Add
    BLAST
    Alternative sequencei668 – 69124Missing in isoform 6 and isoform 8. 2 PublicationsVSP_007278Add
    BLAST
    Alternative sequencei717 – 7259VSLVSAAAA → DCFMDWRTF in isoform 3 and isoform 8. 2 PublicationsVSP_002322
    Alternative sequencei726 – 77045Missing in isoform 3 and isoform 8. 2 PublicationsVSP_002323Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X68362 mRNA. Translation: CAA48422.1.
    X68363 mRNA. Translation: CAA48423.1.
    X68364 mRNA. Translation: CAA48424.1.
    X56230 mRNA. Translation: CAA39679.1.
    AJ296212 mRNA. Translation: CAC34943.1.
    AF508939 mRNA. Translation: AAM34281.1.
    AY177625 mRNA. Translation: AAO45298.1.
    AJ489474 mRNA. Translation: CAD35743.1.
    AK028237 mRNA. Translation: BAC25832.1.
    S65461 mRNA. Translation: AAB28234.1.
    X70324 mRNA. Translation: CAA49791.1.
    X70325 mRNA. Translation: CAA49792.1.
    X51958 mRNA. Translation: CAA36217.1.
    AF095458 mRNA. Translation: AAD25325.1.
    AF095459 mRNA. Translation: AAD25326.1.
    AF095460 mRNA. Translation: AAD25327.1.
    CCDSiCCDS15444.1. [P25425-5]
    PIRiI56187.
    S30293.
    RefSeqiNP_035267.2. NM_011137.3.
    NP_945151.2. NM_198933.3. [P25425-5]
    XP_006496767.1. XM_006496704.1. [P25425-1]
    XP_006496768.1. XM_006496705.1. [P25425-1]
    XP_006496769.1. XM_006496706.1. [P25425-1]
    UniGeneiMm.245261.

    Genome annotation databases

    EnsembliENSMUST00000069609; ENSMUSP00000064000; ENSMUSG00000026565. [P25425-5]
    ENSMUST00000111429; ENSMUSP00000107057; ENSMUSG00000026565. [P25425-2]
    ENSMUST00000160260; ENSMUSP00000124738; ENSMUSG00000026565.
    GeneIDi18986.
    KEGGimmu:18986.
    UCSCiuc007djv.1. mouse. [P25425-6]
    uc007djx.2. mouse. [P25425-5]
    uc007dkb.2. mouse. [P25425-4]
    uc007dkc.2. mouse. [P25425-11]
    uc007dke.1. mouse. [P25425-10]

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X68362 mRNA. Translation: CAA48422.1 .
    X68363 mRNA. Translation: CAA48423.1 .
    X68364 mRNA. Translation: CAA48424.1 .
    X56230 mRNA. Translation: CAA39679.1 .
    AJ296212 mRNA. Translation: CAC34943.1 .
    AF508939 mRNA. Translation: AAM34281.1 .
    AY177625 mRNA. Translation: AAO45298.1 .
    AJ489474 mRNA. Translation: CAD35743.1 .
    AK028237 mRNA. Translation: BAC25832.1 .
    S65461 mRNA. Translation: AAB28234.1 .
    X70324 mRNA. Translation: CAA49791.1 .
    X70325 mRNA. Translation: CAA49792.1 .
    X51958 mRNA. Translation: CAA36217.1 .
    AF095458 mRNA. Translation: AAD25325.1 .
    AF095459 mRNA. Translation: AAD25326.1 .
    AF095460 mRNA. Translation: AAD25327.1 .
    CCDSi CCDS15444.1. [P25425-5 ]
    PIRi I56187.
    S30293.
    RefSeqi NP_035267.2. NM_011137.3.
    NP_945151.2. NM_198933.3. [P25425-5 ]
    XP_006496767.1. XM_006496704.1. [P25425-1 ]
    XP_006496768.1. XM_006496705.1. [P25425-1 ]
    XP_006496769.1. XM_006496706.1. [P25425-1 ]
    UniGenei Mm.245261.

    3D structure databases

    ProteinModelPortali P25425.
    SMRi P25425. Positions 283-441.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 202301. 13 interactions.

    PTM databases

    PhosphoSitei P25425.

    Proteomic databases

    PaxDbi P25425.
    PRIDEi P25425.

    Protocols and materials databases

    DNASUi 18986.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000069609 ; ENSMUSP00000064000 ; ENSMUSG00000026565 . [P25425-5 ]
    ENSMUST00000111429 ; ENSMUSP00000107057 ; ENSMUSG00000026565 . [P25425-2 ]
    ENSMUST00000160260 ; ENSMUSP00000124738 ; ENSMUSG00000026565 .
    GeneIDi 18986.
    KEGGi mmu:18986.
    UCSCi uc007djv.1. mouse. [P25425-6 ]
    uc007djx.2. mouse. [P25425-5 ]
    uc007dkb.2. mouse. [P25425-4 ]
    uc007dkc.2. mouse. [P25425-11 ]
    uc007dke.1. mouse. [P25425-10 ]

    Organism-specific databases

    CTDi 5451.
    MGIi MGI:101898. Pou2f1.

    Phylogenomic databases

    eggNOGi NOG267922.
    GeneTreei ENSGT00750000117373.
    HOVERGENi HBG057016.
    InParanoidi P25425.
    KOi K09364.
    OrthoDBi EOG7DJSMG.
    PhylomeDBi P25425.
    TreeFami TF316413.

    Miscellaneous databases

    ChiTaRSi POU2F1. mouse.
    NextBioi 295362.
    PROi P25425.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P25425.
    Bgeei P25425.
    CleanExi MM_POU2F1.
    Genevestigatori P25425.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR000327. POU_specific.
    IPR000972. TF_octamer.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view ]
    PRINTSi PR00029. OCTAMER.
    PR00028. POUDOMAIN.
    SMARTi SM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Mouse Oct-1 contains a composite homeodomain of human Oct-1 and Oct-2."
      Suzuki N., Peter W., Ciesiolka T., Gruss P., Schoeler H.R.
      Nucleic Acids Res. 21:245-252(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3).
    2. "The nucleotide sequence of mouse OCT-1 cDNA."
      Stepchenko A.G.
      Nucleic Acids Res. 20:1419-1419(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4).
    3. "Tissue-specific isoforms of the ubiquitous transcription factor Oct-1."
      Pankratova E.V., Deyev I.E., Zhenilo S.V., Polanovsky O.L.
      Mol. Genet. Genomics 266:239-245(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5), TISSUE SPECIFICITY.
    4. "Involvement of Oct-1 in transcriptional regulation of beta-casein gene expression in mouse mammary gland."
      Zhao F.-Q., Adachi K., Oka T.
      Biochim. Biophys. Acta 1577:27-37(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
      Strain: C3H/HeN.
      Tissue: Mammary gland.
    5. "Cloning, genomic organization, expression, and effect on beta-casein promoter activity of a novel isoform of the mouse Oct-1 transcription factor."
      Zhao F.-Q., Zheng Y., Dong B., Oka T.
      Gene 326:175-187(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 10), TISSUE SPECIFICITY.
      Tissue: Lung.
    6. "Novel isoforms of mRNA of gene oct-1."
      Deyev I.E., Zhenilo S.V., Pankratova E.V., Polanovsky O.L.
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 11).
      Strain: BALB/c.
      Tissue: Myeloma.
    7. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 12).
      Strain: C57BL/6J.
      Tissue: Embryo.
    8. "CD3 zeta/eta/theta locus is colinear with and transcribed antisense to the gene encoding the transcription factor Oct-1."
      Lerner A., D'Adamio L., Diener A.C., Clayton L.K., Reinherz E.L.
      J. Immunol. 151:3152-3162(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-770.
    9. "Cloning, sequencing and expression of two isoforms of the murine oct-1 transcription factor."
      Jaffe J., Hochberg M., Riss J., Hasin T., Reich L., Laskov R.
      Biochim. Biophys. Acta 1261:201-209(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 30-770 (ISOFORMS 2 AND 6), TISSUE SPECIFICITY.
      Strain: C57BL/6 X DBA/20.
      Tissue: Lymphoid tissue.
    10. "Cloning and sequencing of POU-boxes expressed in mouse testis."
      Goldsborough A., Ashworth A., Willison K.R.
      Nucleic Acids Res. 18:1634-1634(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 305-426.
      Tissue: Testis.
    11. "Expression of novel alternatively spliced isoforms of the oct-1 transcription factor."
      Riss J., Laskov R.
      Biochim. Biophys. Acta 1444:295-298(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 669-770 (ISOFORMS 7; 8 AND 9), TISSUE SPECIFICITY.
      Strain: BALB/c.
      Tissue: Testis.

    Entry informationi

    Entry nameiPO2F1_MOUSE
    AccessioniPrimary (citable) accession number: P25425
    Secondary accession number(s): Q61994
    , Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: April 23, 2003
    Last modified: October 1, 2014
    This is version 147 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3