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P25425

- PO2F1_MOUSE

UniProt

P25425 - PO2F1_MOUSE

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Protein
POU domain, class 2, transcription factor 1
Gene
Pou2f1, Oct-1, Otf-1, Otf1
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi382 – 44160Homeobox
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl
  3. protein binding Source: MGI
  4. sequence-specific DNA binding Source: MGI
Complete GO annotation...

GO - Biological processi

  1. lens induction in camera-type eye Source: MGI
  2. negative regulation of transcription, DNA-templated Source: MGI
  3. olfactory placode formation Source: MGI
  4. positive regulation of transcription from RNA polymerase II promoter Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain, class 2, transcription factor 1
Alternative name(s):
NF-A1
Octamer-binding protein 1
Short name:
Oct-1
Octamer-binding transcription factor 1
Short name:
OTF-1
Gene namesi
Name:Pou2f1
Synonyms:Oct-1, Otf-1, Otf1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 1

Organism-specific databases

MGIiMGI:101898. Pou2f1.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: MGI
  2. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 770770POU domain, class 2, transcription factor 1
PRO_0000100708Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei271 – 2711Phosphothreonine By similarity
Modified residuei284 – 2841Phosphoserine By similarity
Modified residuei388 – 3881Phosphoserine By similarity
Modified residuei451 – 4511Phosphoserine By similarity

Post-translational modificationi

Phosphorylated by PRKDC By similarity.

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP25425.
PRIDEiP25425.

PTM databases

PhosphoSiteiP25425.

Expressioni

Tissue specificityi

Ubiquitously expressed. However, isoforms 4 and 5 are only expressed in lymphocytes.4 Publications

Gene expression databases

ArrayExpressiP25425.
BgeeiP25425.
CleanExiMM_POU2F1.
GenevestigatoriP25425.

Interactioni

Subunit structurei

Interacts with NR3C1, AR, PGR and HCFC1 By similarity.

Protein-protein interaction databases

BioGridi202301. 13 interactions.

Structurei

3D structure databases

ProteinModelPortaliP25425.
SMRiP25425. Positions 283-441.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini281 – 35575POU-specific
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiNOG267922.
GeneTreeiENSGT00750000117373.
HOVERGENiHBG057016.
InParanoidiP25425.
KOiK09364.
OrthoDBiEOG7DJSMG.
PhylomeDBiP25425.
TreeFamiTF316413.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequences (12)i

Sequence statusi: Complete.

This entry describes 12 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: P25425-1) [UniParc]FASTAAdd to Basket

Also known as: OCT-1A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MNNPSETNKS SMESEDASTG TQTNGLDFQK QPVPVGGAIS TAQAQAFLGH    50
LHQVQLAGTS LQAAAQSLNV QSKSSEESGD SQQSSQPSSQ PPSVQSAIPQ 100
TQLMLAGGQI TGLTLTPAQQ QLLLQQAQAQ AQLLAAAVQQ HSASQQHSAA 150
GATISASAAT PMTQIPLSQP IQIAQDLQQL QQLQQQNLNL QQFVLVHPTT 200
NLQPAQFIIS QTPQGQQGLL QAQNLLTQLP QQSQANLLQP QPSITLTSQP 250
TTPTRTIAAA SVQTLPQSQS TPKRIDTPSL EEPSDLEELE QFAKTFKQRR 300
IKLGFTQGDV GLAMGKLYGN DFSQTTISRF EALNLSFKNM CKLKPLLEKW 350
LNDAENLSSD STASSPSALN SPGLGAEGLN RRRKKRTSIE TNIRVALEKS 400
FMENQKPTSE DITLIAEQLN MEKEVIRVWF CNRRQKEKRI NPPSSGGTSS 450
SPIKAIFPSP ASLVATTPSL VTSSTATTLT VNPVLPLTSA AVTNLSLTDQ 500
DLRRGCSWEV LRSLPDRVTT TAGTTDSTSN NNTATVISTA PPASSAVTSP 550
SLSPSPSASA STSEASSASE TNTTQTTSTP LPSPLGASQV MVTTPGLQTA 600
AAALQGAAQL PANASLAAMA AAAGLSPGLM APSQFAAGGA LLSLSPGTLG 650
SALSPALMSN STLATIQALA SSGSLPITSL DATGNLVFAN AGGAPNIVTA 700
PLFLNPQNLS LLTSNPVSLV SAAAASTGNS APTASLHASS TSTESIQSSL 750
FTVASASGPA STTTAASKAQ 770
Length:770
Mass (Da):79,547
Last modified:April 23, 2003 - v3
Checksum:iB45CDBE632853FE9
GO
Isoform 2 (identifier: P25425-2) [UniParc]FASTAAdd to Basket

Also known as: OCT-1B

The sequence of this isoform differs from the canonical sequence as follows:
     499-522: Missing.

Show »
Length:746
Mass (Da):76,790
Checksum:iA19E2D4CB6C147A2
GO
Isoform 3 (identifier: P25425-3) [UniParc]FASTAAdd to Basket

Also known as: OCT-1C

The sequence of this isoform differs from the canonical sequence as follows:
     499-522: Missing.
     717-725: VSLVSAAAA → DCFMDWRTF
     726-770: Missing.

Show »
Length:701
Mass (Da):72,983
Checksum:i85CEC91D2241D0D9
GO
Isoform 4 (identifier: P25425-4) [UniParc]FASTAAdd to Basket

Also known as: OCT-1R

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLDCSDCVLDSRM
     54-71: Missing.
     499-522: Missing.
     639-770: Missing.

Show »
Length:608
Mass (Da):63,780
Checksum:iED52028C67A99D5C
GO
Isoform 5 (identifier: P25425-5) [UniParc]FASTAAdd to Basket

Also known as: OCT-1L

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLDCSDCVLDSRM
     499-522: Missing.

Show »
Length:758
Mass (Da):78,128
Checksum:iEF08D83A224B2418
GO
Isoform 6 (identifier: P25425-6) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     668-691: Missing.

Show »
Length:746
Mass (Da):77,274
Checksum:iAEBEE16A471595D4
GO
Isoform 7 (identifier: P25425-7) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     639-641: GAL → SCF
     642-770: Missing.

Show »
Length:641
Mass (Da):67,317
Checksum:iBD83AEBFA5C51643
GO
Isoform 8 (identifier: P25425-8) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     668-691: Missing.
     717-725: VSLVSAAAA → DCFMDWRTF
     726-770: Missing.

Show »
Length:701
Mass (Da):73,467
Checksum:iF1092FC5322C5061
GO
Isoform 9 (identifier: P25425-9) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     639-647: GALLSLSPG → IASWIGELS
     648-770: Missing.

Show »
Length:647
Mass (Da):67,937
Checksum:iD59952DB1E8D61F0
GO
Isoform 10 (identifier: P25425-10) [UniParc]FASTAAdd to Basket

Also known as: OCT-1Z

The sequence of this isoform differs from the canonical sequence as follows:
     499-522: DQDLRRGCSWEVLRSLPDRVTTTA → GKQQPAYRLVSTVPVRFLWRTARS
     523-770: Missing.

Show »
Length:522
Mass (Da):56,193
Checksum:i6ABAAA323C1F873B
GO
Isoform 11 (identifier: P25425-11) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLDCSDCVLDSRM
     639-770: Missing.

Show »
Length:650
Mass (Da):68,318
Checksum:i649DDF3D7105D736
GO
Isoform 12 (identifier: P25425-12) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MADGGAASQDESSAAAAAAADSR

Note: No experimental confirmation available.

Show »
Length:792
Mass (Da):81,479
Checksum:i96B1978640108D06
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 11M → MADGGAASQDESSAAAAAAA DSR in isoform 12.
VSP_013403
Alternative sequencei1 – 11M → MLDCSDCVLDSRM in isoform 4, isoform 5 and isoform 11.
VSP_007271
Alternative sequencei54 – 7118Missing in isoform 4.
VSP_007272Add
BLAST
Alternative sequencei499 – 52224DQDLR…VTTTA → GKQQPAYRLVSTVPVRFLWR TARS in isoform 10.
VSP_013404Add
BLAST
Alternative sequencei499 – 52224Missing in isoform 2, isoform 3, isoform 4 and isoform 5.
VSP_002321Add
BLAST
Alternative sequencei523 – 770248Missing in isoform 10.
VSP_013405Add
BLAST
Alternative sequencei639 – 770132Missing in isoform 4 and isoform 11.
VSP_007273Add
BLAST
Alternative sequencei639 – 6479GALLSLSPG → IASWIGELS in isoform 9.
VSP_007274
Alternative sequencei639 – 6413GAL → SCF in isoform 7.
VSP_007276
Alternative sequencei642 – 770129Missing in isoform 7.
VSP_007277Add
BLAST
Alternative sequencei648 – 770123Missing in isoform 9.
VSP_007275Add
BLAST
Alternative sequencei668 – 69124Missing in isoform 6 and isoform 8.
VSP_007278Add
BLAST
Alternative sequencei717 – 7259VSLVSAAAA → DCFMDWRTF in isoform 3 and isoform 8.
VSP_002322
Alternative sequencei726 – 77045Missing in isoform 3 and isoform 8.
VSP_002323Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti43 – 431Q → L in CAA39679. 1 Publication
Sequence conflicti70 – 701V → I in CAC34943. 1 Publication
Sequence conflicti129 – 1291A → P1 Publication
Sequence conflicti168 – 1681S → C in CAD35743. 1 Publication
Sequence conflicti188 – 1881L → H in CAC34943. 1 Publication
Sequence conflicti234 – 2341Q → R in CAC34943. 1 Publication
Sequence conflicti333 – 3331L → W1 Publication
Sequence conflicti360 – 3601D → G in CAC34943. 1 Publication
Sequence conflicti368 – 3681A → D1 Publication
Sequence conflicti441 – 4411N → D in CAC34943. 1 Publication
Sequence conflicti474 – 4741S → G in CAC34943. 1 Publication
Sequence conflicti596 – 5961G → D in CAC34943. 1 Publication
Sequence conflicti608 – 6081A → G in CAA48422. 1 Publication
Sequence conflicti608 – 6081A → G in CAA48423. 1 Publication
Sequence conflicti608 – 6081A → G in CAA48424. 1 Publication
Sequence conflicti609 – 6091Q → R in CAC34943. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X68362 mRNA. Translation: CAA48422.1.
X68363 mRNA. Translation: CAA48423.1.
X68364 mRNA. Translation: CAA48424.1.
X56230 mRNA. Translation: CAA39679.1.
AJ296212 mRNA. Translation: CAC34943.1.
AF508939 mRNA. Translation: AAM34281.1.
AY177625 mRNA. Translation: AAO45298.1.
AJ489474 mRNA. Translation: CAD35743.1.
AK028237 mRNA. Translation: BAC25832.1.
S65461 mRNA. Translation: AAB28234.1.
X70324 mRNA. Translation: CAA49791.1.
X70325 mRNA. Translation: CAA49792.1.
X51958 mRNA. Translation: CAA36217.1.
AF095458 mRNA. Translation: AAD25325.1.
AF095459 mRNA. Translation: AAD25326.1.
AF095460 mRNA. Translation: AAD25327.1.
CCDSiCCDS15444.1. [P25425-5]
PIRiI56187.
S30293.
RefSeqiNP_035267.2. NM_011137.3.
NP_945151.2. NM_198933.3. [P25425-5]
XP_006496767.1. XM_006496704.1. [P25425-1]
XP_006496768.1. XM_006496705.1. [P25425-1]
XP_006496769.1. XM_006496706.1. [P25425-1]
UniGeneiMm.245261.

Genome annotation databases

EnsembliENSMUST00000069609; ENSMUSP00000064000; ENSMUSG00000026565. [P25425-5]
ENSMUST00000111429; ENSMUSP00000107057; ENSMUSG00000026565. [P25425-2]
ENSMUST00000160260; ENSMUSP00000124738; ENSMUSG00000026565.
GeneIDi18986.
KEGGimmu:18986.
UCSCiuc007djv.1. mouse. [P25425-6]
uc007djx.2. mouse. [P25425-5]
uc007dkb.2. mouse. [P25425-4]
uc007dkc.2. mouse. [P25425-11]
uc007dke.1. mouse. [P25425-10]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X68362 mRNA. Translation: CAA48422.1 .
X68363 mRNA. Translation: CAA48423.1 .
X68364 mRNA. Translation: CAA48424.1 .
X56230 mRNA. Translation: CAA39679.1 .
AJ296212 mRNA. Translation: CAC34943.1 .
AF508939 mRNA. Translation: AAM34281.1 .
AY177625 mRNA. Translation: AAO45298.1 .
AJ489474 mRNA. Translation: CAD35743.1 .
AK028237 mRNA. Translation: BAC25832.1 .
S65461 mRNA. Translation: AAB28234.1 .
X70324 mRNA. Translation: CAA49791.1 .
X70325 mRNA. Translation: CAA49792.1 .
X51958 mRNA. Translation: CAA36217.1 .
AF095458 mRNA. Translation: AAD25325.1 .
AF095459 mRNA. Translation: AAD25326.1 .
AF095460 mRNA. Translation: AAD25327.1 .
CCDSi CCDS15444.1. [P25425-5 ]
PIRi I56187.
S30293.
RefSeqi NP_035267.2. NM_011137.3.
NP_945151.2. NM_198933.3. [P25425-5 ]
XP_006496767.1. XM_006496704.1. [P25425-1 ]
XP_006496768.1. XM_006496705.1. [P25425-1 ]
XP_006496769.1. XM_006496706.1. [P25425-1 ]
UniGenei Mm.245261.

3D structure databases

ProteinModelPortali P25425.
SMRi P25425. Positions 283-441.
ModBasei Search...

Protein-protein interaction databases

BioGridi 202301. 13 interactions.

PTM databases

PhosphoSitei P25425.

Proteomic databases

PaxDbi P25425.
PRIDEi P25425.

Protocols and materials databases

DNASUi 18986.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000069609 ; ENSMUSP00000064000 ; ENSMUSG00000026565 . [P25425-5 ]
ENSMUST00000111429 ; ENSMUSP00000107057 ; ENSMUSG00000026565 . [P25425-2 ]
ENSMUST00000160260 ; ENSMUSP00000124738 ; ENSMUSG00000026565 .
GeneIDi 18986.
KEGGi mmu:18986.
UCSCi uc007djv.1. mouse. [P25425-6 ]
uc007djx.2. mouse. [P25425-5 ]
uc007dkb.2. mouse. [P25425-4 ]
uc007dkc.2. mouse. [P25425-11 ]
uc007dke.1. mouse. [P25425-10 ]

Organism-specific databases

CTDi 5451.
MGIi MGI:101898. Pou2f1.

Phylogenomic databases

eggNOGi NOG267922.
GeneTreei ENSGT00750000117373.
HOVERGENi HBG057016.
InParanoidi P25425.
KOi K09364.
OrthoDBi EOG7DJSMG.
PhylomeDBi P25425.
TreeFami TF316413.

Miscellaneous databases

ChiTaRSi POU2F1. mouse.
NextBioi 295362.
PROi P25425.
SOURCEi Search...

Gene expression databases

ArrayExpressi P25425.
Bgeei P25425.
CleanExi MM_POU2F1.
Genevestigatori P25425.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
IPR000972. TF_octamer.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view ]
PRINTSi PR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTi SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Mouse Oct-1 contains a composite homeodomain of human Oct-1 and Oct-2."
    Suzuki N., Peter W., Ciesiolka T., Gruss P., Schoeler H.R.
    Nucleic Acids Res. 21:245-252(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3).
  2. "The nucleotide sequence of mouse OCT-1 cDNA."
    Stepchenko A.G.
    Nucleic Acids Res. 20:1419-1419(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4).
  3. "Tissue-specific isoforms of the ubiquitous transcription factor Oct-1."
    Pankratova E.V., Deyev I.E., Zhenilo S.V., Polanovsky O.L.
    Mol. Genet. Genomics 266:239-245(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5), TISSUE SPECIFICITY.
  4. "Involvement of Oct-1 in transcriptional regulation of beta-casein gene expression in mouse mammary gland."
    Zhao F.-Q., Adachi K., Oka T.
    Biochim. Biophys. Acta 1577:27-37(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    Strain: C3H/HeN.
    Tissue: Mammary gland.
  5. "Cloning, genomic organization, expression, and effect on beta-casein promoter activity of a novel isoform of the mouse Oct-1 transcription factor."
    Zhao F.-Q., Zheng Y., Dong B., Oka T.
    Gene 326:175-187(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 10), TISSUE SPECIFICITY.
    Tissue: Lung.
  6. "Novel isoforms of mRNA of gene oct-1."
    Deyev I.E., Zhenilo S.V., Pankratova E.V., Polanovsky O.L.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 11).
    Strain: BALB/c.
    Tissue: Myeloma.
  7. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 12).
    Strain: C57BL/6J.
    Tissue: Embryo.
  8. "CD3 zeta/eta/theta locus is colinear with and transcribed antisense to the gene encoding the transcription factor Oct-1."
    Lerner A., D'Adamio L., Diener A.C., Clayton L.K., Reinherz E.L.
    J. Immunol. 151:3152-3162(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-770.
  9. "Cloning, sequencing and expression of two isoforms of the murine oct-1 transcription factor."
    Jaffe J., Hochberg M., Riss J., Hasin T., Reich L., Laskov R.
    Biochim. Biophys. Acta 1261:201-209(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 30-770 (ISOFORMS 2 AND 6), TISSUE SPECIFICITY.
    Strain: C57BL/6 X DBA/20.
    Tissue: Lymphoid tissue.
  10. "Cloning and sequencing of POU-boxes expressed in mouse testis."
    Goldsborough A., Ashworth A., Willison K.R.
    Nucleic Acids Res. 18:1634-1634(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 305-426.
    Tissue: Testis.
  11. "Expression of novel alternatively spliced isoforms of the oct-1 transcription factor."
    Riss J., Laskov R.
    Biochim. Biophys. Acta 1444:295-298(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 669-770 (ISOFORMS 7; 8 AND 9), TISSUE SPECIFICITY.
    Strain: BALB/c.
    Tissue: Testis.

Entry informationi

Entry nameiPO2F1_MOUSE
AccessioniPrimary (citable) accession number: P25425
Secondary accession number(s): Q61994
, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: April 23, 2003
Last modified: July 9, 2014
This is version 146 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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