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Protein

Chaperone protein FaeE

Gene

faeE

Organism
Escherichia coli
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Mediates assembly of pili by forming soluble multimeric complexes with pili subunits as an intermediate step in the assembly process. This protein is involved in K88 pili assembly. Protects pilin protein from proteolytic degradation by DegP and from premature polymerization.

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processFimbrium biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein FaeE
Gene namesi
Name:faeE
Encoded oniPlasmid pFM2050 Publication
OrganismiEscherichia coli
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 34Sequence analysisAdd BLAST34
ChainiPRO_000000927035 – 258Chaperone protein FaeEAdd BLAST224

Proteomic databases

PRIDEiP25401

Structurei

Secondary structure

1258
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi36 – 39Combined sources4
Beta strandi41 – 46Combined sources6
Beta strandi52 – 58Combined sources7
Beta strandi61 – 63Combined sources3
Beta strandi65 – 75Combined sources11
Beta strandi82 – 92Combined sources11
Beta strandi97 – 104Combined sources8
Beta strandi111 – 113Combined sources3
Beta strandi115 – 124Combined sources10
Beta strandi129 – 132Combined sources4
Beta strandi135 – 146Combined sources12
Helixi148 – 150Combined sources3
Helixi157 – 160Combined sources4
Beta strandi162 – 165Combined sources4
Beta strandi171 – 174Combined sources4
Beta strandi177 – 179Combined sources3
Beta strandi183 – 188Combined sources6
Beta strandi191 – 193Combined sources3
Helixi198 – 204Combined sources7
Beta strandi212 – 214Combined sources3
Beta strandi219 – 225Combined sources7
Beta strandi231 – 237Combined sources7
Turni243 – 245Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3F65X-ray2.29A/B/C/D/E/F/G/H35-258[»]
3F6IX-ray2.79A/B35-258[»]
3F6LX-ray2.80A/B35-258[»]
3GEWX-ray2.00B/C35-258[»]
3GFUX-ray1.99A/C35-258[»]
ProteinModelPortaliP25401
SMRiP25401
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP25401

Family & Domainsi

Sequence similaritiesi

Belongs to the periplasmic pilus chaperone family.Curated

Keywords - Domaini

Immunoglobulin domain, Signal

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR008962 PapD-like_sf
IPR036316 Pili_assmbl_chap_C_dom_sf
IPR001829 Pili_assmbl_chaperone_bac
IPR018046 Pili_assmbl_chaperone_CS
IPR016147 Pili_assmbl_chaperone_N
PfamiView protein in Pfam
PF00345 PapD_N, 1 hit
PRINTSiPR00969 CHAPERONPILI
SUPFAMiSSF49354 SSF49354, 1 hit
SSF49584 SSF49584, 1 hit
PROSITEiView protein in PROSITE
PS00635 PILI_CHAPERONE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P25401-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKRNAVTTF FTNRVTKALG MTLALMMTCQ SAMASLAVDQ TRYIFRGDKD
60 70 80 90 100
ALTITVTNND KERTFGGQAW VDNIVEKDTR PTFVVTPSFF KVKPNGQQTL
110 120 130 140 150
RIIMASDHLP KDKESVYWLN LQDIPPALEG SGIAVALRTK LKLFYRPKAL
160 170 180 190 200
LEGRKGAEEG ISLQSRPDGR TMLVNTTPYI FAIGSLLDGN GKKIATDNGT
210 220 230 240 250
TQKLLMFMPG DEVQVKGNVV KVDSLNDYGE LQTWTINKKK PAAPEAAKAE

KADTAEQK
Length:258
Mass (Da):28,478
Last modified:May 1, 1992 - v1
Checksum:iFF80904B3DE5420B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56003 Genomic DNA Translation: CAA39478.1
Z11699 Genomic DNA Translation: CAA77756.1
PIRiS15227
RefSeqiWP_000044493.1, NZ_NXMG01000096.1

Similar proteinsi

Entry informationi

Entry nameiFAEE_ECOLX
AccessioniPrimary (citable) accession number: P25401
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Plasmid

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