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P25370

- GFD2_YEAST

UniProt

P25370 - GFD2_YEAST

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Protein

Good for full DBP5 activity protein 2

Gene
GFD2, YCL036W, YCL187, YCL36W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

High-copy suppressor of DBP5 mutation.1 Publication

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29295-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Good for full DBP5 activity protein 2
Gene namesi
Name:GFD2
Ordered Locus Names:YCL036W
ORF Names:YCL187, YCL36W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome III

Organism-specific databases

CYGDiYCL036w.
SGDiS000000541. GFD2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 566566Good for full DBP5 activity protein 2PRO_0000202543Add
BLAST

Proteomic databases

MaxQBiP25370.
PaxDbiP25370.

Expressioni

Gene expression databases

GenevestigatoriP25370.

Interactioni

Protein-protein interaction databases

BioGridi30947. 15 interactions.
DIPiDIP-2955N.
MINTiMINT-2733307.
STRINGi4932.YCL036W.

Structurei

3D structure databases

ProteinModelPortaliP25370.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG260195.
GeneTreeiENSGT00530000066839.
OMAiTHINGMR.
OrthoDBiEOG7FZ08N.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR012337. RNaseH-like_dom.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

P25370-1 [UniParc]FASTAAdd to Basket

« Hide

MQVQKMVRDN SNNGSDKSVH WERRNNNGAG PRYRSRSGNT GALATKLSNG    50
TLSVRGLVKD RTGSGKIAGC VEAFLDARTQ LNTPWDRAKC NWLDQIDYYV 100
QLRKTAFSKE LDQLRKPMID AYVAEMRQKF DASYGQSRAQ LEAKLAQVDS 150
EWHMVHGDVH AKLEKLVEER RFLKRLSDTI VPPRSKRSQR LSPLTKEDRA 200
NCICPQPKGM SDTAWFEAIQ KKMLGMNGTI KLLETEQKLL ADEKNSVRKT 250
FWPMVEAHSR SNEFAYLEKC IRLMASQRAI CFCLDIEAFE TNQNVITEIG 300
ISIYDPRENM VPSMVPITKN YHLIIEESLE LRNQKWVCDY KDCYLLGESY 350
VLSLKECVHF IQSLINYYLV PVTEEDKTWS RAFVGHHVSG DLKWLETIGV 400
KFPGRGYEGH LDHTLLLAET PGDLDVFILD TEQFYRKSYG EKGSSLGKIL 450
RLFEIPHAFL HNAGNDAYYT LHLFMKFCDV NFRKISGMDD VLKVMGQVKV 500
WGERDVREPK VVPMSYAISI EEAVKNRTYR KGVKSSRKER VCQTEFGGLT 550
YFGTAKDAFT STLPTH 566
Length:566
Mass (Da):64,913
Last modified:May 1, 1992 - v1
Checksum:i8F84105DD8772A9B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X59720 Genomic DNA. Translation: CAA42380.1.
BK006937 Genomic DNA. Translation: DAA07448.1.
PIRiS17477.
RefSeqiNP_009894.1. NM_001178681.1.

Genome annotation databases

EnsemblFungiiYCL036W; YCL036W; YCL036W.
GeneIDi850321.
KEGGisce:YCL036W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X59720 Genomic DNA. Translation: CAA42380.1 .
BK006937 Genomic DNA. Translation: DAA07448.1 .
PIRi S17477.
RefSeqi NP_009894.1. NM_001178681.1.

3D structure databases

ProteinModelPortali P25370.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 30947. 15 interactions.
DIPi DIP-2955N.
MINTi MINT-2733307.
STRINGi 4932.YCL036W.

Proteomic databases

MaxQBi P25370.
PaxDbi P25370.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YCL036W ; YCL036W ; YCL036W .
GeneIDi 850321.
KEGGi sce:YCL036W.

Organism-specific databases

CYGDi YCL036w.
SGDi S000000541. GFD2.

Phylogenomic databases

eggNOGi NOG260195.
GeneTreei ENSGT00530000066839.
OMAi THINGMR.
OrthoDBi EOG7FZ08N.

Enzyme and pathway databases

BioCyci YEAST:G3O-29295-MONOMER.

Miscellaneous databases

NextBioi 965733.

Gene expression databases

Genevestigatori P25370.

Family and domain databases

Gene3Di 3.30.420.10. 1 hit.
InterProi IPR012337. RNaseH-like_dom.
[Graphical view ]
SUPFAMi SSF53098. SSF53098. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The complete sequence of a 11,953 bp fragment from C1G on chromosome III encompasses four new open reading frames."
    Rad M.R., Luetzenkirchen K., Xu G., Kleinhans U., Hollenberg C.P.
    Yeast 7:533-538(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The complete DNA sequence of yeast chromosome III."
    Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
    , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
    Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components."
    Estruch F., Cole C.N.
    Mol. Biol. Cell 14:1664-1676(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION, FUNCTION.

Entry informationi

Entry nameiGFD2_YEAST
AccessioniPrimary (citable) accession number: P25370
Secondary accession number(s): D6VQX9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: September 3, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

External Data

Dasty 3

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