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P25370

- GFD2_YEAST

UniProt

P25370 - GFD2_YEAST

Protein

Good for full DBP5 activity protein 2

Gene

GFD2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 May 1992)
      Previous versions | rss
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    Functioni

    High-copy suppressor of DBP5 mutation.1 Publication

    GO - Molecular functioni

    1. nucleic acid binding Source: InterPro

    Enzyme and pathway databases

    BioCyciYEAST:G3O-29295-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Good for full DBP5 activity protein 2
    Gene namesi
    Name:GFD2
    Ordered Locus Names:YCL036W
    ORF Names:YCL187, YCL36W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome III

    Organism-specific databases

    CYGDiYCL036w.
    SGDiS000000541. GFD2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 566566Good for full DBP5 activity protein 2PRO_0000202543Add
    BLAST

    Proteomic databases

    MaxQBiP25370.
    PaxDbiP25370.

    Expressioni

    Gene expression databases

    GenevestigatoriP25370.

    Interactioni

    Protein-protein interaction databases

    BioGridi30947. 15 interactions.
    DIPiDIP-2955N.
    MINTiMINT-2733307.
    STRINGi4932.YCL036W.

    Structurei

    3D structure databases

    ProteinModelPortaliP25370.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG260195.
    GeneTreeiENSGT00530000066839.
    OMAiTHINGMR.
    OrthoDBiEOG7FZ08N.

    Family and domain databases

    Gene3Di3.30.420.10. 1 hit.
    InterProiIPR012337. RNaseH-like_dom.
    [Graphical view]
    SUPFAMiSSF53098. SSF53098. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P25370-1 [UniParc]FASTAAdd to Basket

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    MQVQKMVRDN SNNGSDKSVH WERRNNNGAG PRYRSRSGNT GALATKLSNG    50
    TLSVRGLVKD RTGSGKIAGC VEAFLDARTQ LNTPWDRAKC NWLDQIDYYV 100
    QLRKTAFSKE LDQLRKPMID AYVAEMRQKF DASYGQSRAQ LEAKLAQVDS 150
    EWHMVHGDVH AKLEKLVEER RFLKRLSDTI VPPRSKRSQR LSPLTKEDRA 200
    NCICPQPKGM SDTAWFEAIQ KKMLGMNGTI KLLETEQKLL ADEKNSVRKT 250
    FWPMVEAHSR SNEFAYLEKC IRLMASQRAI CFCLDIEAFE TNQNVITEIG 300
    ISIYDPRENM VPSMVPITKN YHLIIEESLE LRNQKWVCDY KDCYLLGESY 350
    VLSLKECVHF IQSLINYYLV PVTEEDKTWS RAFVGHHVSG DLKWLETIGV 400
    KFPGRGYEGH LDHTLLLAET PGDLDVFILD TEQFYRKSYG EKGSSLGKIL 450
    RLFEIPHAFL HNAGNDAYYT LHLFMKFCDV NFRKISGMDD VLKVMGQVKV 500
    WGERDVREPK VVPMSYAISI EEAVKNRTYR KGVKSSRKER VCQTEFGGLT 550
    YFGTAKDAFT STLPTH 566
    Length:566
    Mass (Da):64,913
    Last modified:May 1, 1992 - v1
    Checksum:i8F84105DD8772A9B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59720 Genomic DNA. Translation: CAA42380.1.
    BK006937 Genomic DNA. Translation: DAA07448.1.
    PIRiS17477.
    RefSeqiNP_009894.1. NM_001178681.1.

    Genome annotation databases

    EnsemblFungiiYCL036W; YCL036W; YCL036W.
    GeneIDi850321.
    KEGGisce:YCL036W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59720 Genomic DNA. Translation: CAA42380.1 .
    BK006937 Genomic DNA. Translation: DAA07448.1 .
    PIRi S17477.
    RefSeqi NP_009894.1. NM_001178681.1.

    3D structure databases

    ProteinModelPortali P25370.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 30947. 15 interactions.
    DIPi DIP-2955N.
    MINTi MINT-2733307.
    STRINGi 4932.YCL036W.

    Proteomic databases

    MaxQBi P25370.
    PaxDbi P25370.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YCL036W ; YCL036W ; YCL036W .
    GeneIDi 850321.
    KEGGi sce:YCL036W.

    Organism-specific databases

    CYGDi YCL036w.
    SGDi S000000541. GFD2.

    Phylogenomic databases

    eggNOGi NOG260195.
    GeneTreei ENSGT00530000066839.
    OMAi THINGMR.
    OrthoDBi EOG7FZ08N.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-29295-MONOMER.

    Miscellaneous databases

    NextBioi 965733.

    Gene expression databases

    Genevestigatori P25370.

    Family and domain databases

    Gene3Di 3.30.420.10. 1 hit.
    InterProi IPR012337. RNaseH-like_dom.
    [Graphical view ]
    SUPFAMi SSF53098. SSF53098. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete sequence of a 11,953 bp fragment from C1G on chromosome III encompasses four new open reading frames."
      Rad M.R., Luetzenkirchen K., Xu G., Kleinhans U., Hollenberg C.P.
      Yeast 7:533-538(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "The complete DNA sequence of yeast chromosome III."
      Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
      , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
      Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components."
      Estruch F., Cole C.N.
      Mol. Biol. Cell 14:1664-1676(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION, FUNCTION.

    Entry informationi

    Entry nameiGFD2_YEAST
    AccessioniPrimary (citable) accession number: P25370
    Secondary accession number(s): D6VQX9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: May 1, 1992
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome III
      Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

    External Data

    Dasty 3