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Protein

Good for full DBP5 activity protein 2

Gene

GFD2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

High-copy suppressor of DBP5 mutation.1 Publication

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29295-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Good for full DBP5 activity protein 2
Gene namesi
Name:GFD2
Ordered Locus Names:YCL036W
ORF Names:YCL187, YCL36W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome III

Organism-specific databases

CYGDiYCL036w.
EuPathDBiFungiDB:YCL036W.
SGDiS000000541. GFD2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 566566Good for full DBP5 activity protein 2PRO_0000202543Add
BLAST

Proteomic databases

MaxQBiP25370.
PaxDbiP25370.

Interactioni

Protein-protein interaction databases

BioGridi30947. 16 interactions.
DIPiDIP-2955N.
MINTiMINT-2733307.

Structurei

3D structure databases

ProteinModelPortaliP25370.
SMRiP25370. Positions 277-475.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG260195.
GeneTreeiENSGT00530000066839.
InParanoidiP25370.
OMAiTHINGMR.
OrthoDBiEOG7FZ08N.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR012337. RNaseH-like_dom.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

P25370-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVQKMVRDN SNNGSDKSVH WERRNNNGAG PRYRSRSGNT GALATKLSNG
60 70 80 90 100
TLSVRGLVKD RTGSGKIAGC VEAFLDARTQ LNTPWDRAKC NWLDQIDYYV
110 120 130 140 150
QLRKTAFSKE LDQLRKPMID AYVAEMRQKF DASYGQSRAQ LEAKLAQVDS
160 170 180 190 200
EWHMVHGDVH AKLEKLVEER RFLKRLSDTI VPPRSKRSQR LSPLTKEDRA
210 220 230 240 250
NCICPQPKGM SDTAWFEAIQ KKMLGMNGTI KLLETEQKLL ADEKNSVRKT
260 270 280 290 300
FWPMVEAHSR SNEFAYLEKC IRLMASQRAI CFCLDIEAFE TNQNVITEIG
310 320 330 340 350
ISIYDPRENM VPSMVPITKN YHLIIEESLE LRNQKWVCDY KDCYLLGESY
360 370 380 390 400
VLSLKECVHF IQSLINYYLV PVTEEDKTWS RAFVGHHVSG DLKWLETIGV
410 420 430 440 450
KFPGRGYEGH LDHTLLLAET PGDLDVFILD TEQFYRKSYG EKGSSLGKIL
460 470 480 490 500
RLFEIPHAFL HNAGNDAYYT LHLFMKFCDV NFRKISGMDD VLKVMGQVKV
510 520 530 540 550
WGERDVREPK VVPMSYAISI EEAVKNRTYR KGVKSSRKER VCQTEFGGLT
560
YFGTAKDAFT STLPTH
Length:566
Mass (Da):64,913
Last modified:May 1, 1992 - v1
Checksum:i8F84105DD8772A9B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42380.1.
BK006937 Genomic DNA. Translation: DAA07448.1.
PIRiS17477.
RefSeqiNP_009894.1. NM_001178681.1.

Genome annotation databases

EnsemblFungiiYCL036W; YCL036W; YCL036W.
GeneIDi850321.
KEGGisce:YCL036W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42380.1.
BK006937 Genomic DNA. Translation: DAA07448.1.
PIRiS17477.
RefSeqiNP_009894.1. NM_001178681.1.

3D structure databases

ProteinModelPortaliP25370.
SMRiP25370. Positions 277-475.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi30947. 16 interactions.
DIPiDIP-2955N.
MINTiMINT-2733307.

Proteomic databases

MaxQBiP25370.
PaxDbiP25370.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYCL036W; YCL036W; YCL036W.
GeneIDi850321.
KEGGisce:YCL036W.

Organism-specific databases

CYGDiYCL036w.
EuPathDBiFungiDB:YCL036W.
SGDiS000000541. GFD2.

Phylogenomic databases

eggNOGiNOG260195.
GeneTreeiENSGT00530000066839.
InParanoidiP25370.
OMAiTHINGMR.
OrthoDBiEOG7FZ08N.

Enzyme and pathway databases

BioCyciYEAST:G3O-29295-MONOMER.

Miscellaneous databases

NextBioi965733.
PROiP25370.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR012337. RNaseH-like_dom.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The complete sequence of a 11,953 bp fragment from C1G on chromosome III encompasses four new open reading frames."
    Rad M.R., Luetzenkirchen K., Xu G., Kleinhans U., Hollenberg C.P.
    Yeast 7:533-538(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The complete DNA sequence of yeast chromosome III."
    Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
    , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
    Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components."
    Estruch F., Cole C.N.
    Mol. Biol. Cell 14:1664-1676(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION, FUNCTION.

Entry informationi

Entry nameiGFD2_YEAST
AccessioniPrimary (citable) accession number: P25370
Secondary accession number(s): D6VQX9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: July 22, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.