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P25370 (GFD2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Good for full DBP5 activity protein 2
Gene names
Name:GFD2
Ordered Locus Names:YCL036W
ORF Names:YCL187, YCL36W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length566 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

High-copy suppressor of DBP5 mutation. Ref.4

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionnucleic acid binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 566566Good for full DBP5 activity protein 2
PRO_0000202543

Sequences

Sequence LengthMass (Da)Tools
P25370 [UniParc].

Last modified May 1, 1992. Version 1.
Checksum: 8F84105DD8772A9B

FASTA56664,913
        10         20         30         40         50         60 
MQVQKMVRDN SNNGSDKSVH WERRNNNGAG PRYRSRSGNT GALATKLSNG TLSVRGLVKD 

        70         80         90        100        110        120 
RTGSGKIAGC VEAFLDARTQ LNTPWDRAKC NWLDQIDYYV QLRKTAFSKE LDQLRKPMID 

       130        140        150        160        170        180 
AYVAEMRQKF DASYGQSRAQ LEAKLAQVDS EWHMVHGDVH AKLEKLVEER RFLKRLSDTI 

       190        200        210        220        230        240 
VPPRSKRSQR LSPLTKEDRA NCICPQPKGM SDTAWFEAIQ KKMLGMNGTI KLLETEQKLL 

       250        260        270        280        290        300 
ADEKNSVRKT FWPMVEAHSR SNEFAYLEKC IRLMASQRAI CFCLDIEAFE TNQNVITEIG 

       310        320        330        340        350        360 
ISIYDPRENM VPSMVPITKN YHLIIEESLE LRNQKWVCDY KDCYLLGESY VLSLKECVHF 

       370        380        390        400        410        420 
IQSLINYYLV PVTEEDKTWS RAFVGHHVSG DLKWLETIGV KFPGRGYEGH LDHTLLLAET 

       430        440        450        460        470        480 
PGDLDVFILD TEQFYRKSYG EKGSSLGKIL RLFEIPHAFL HNAGNDAYYT LHLFMKFCDV 

       490        500        510        520        530        540 
NFRKISGMDD VLKVMGQVKV WGERDVREPK VVPMSYAISI EEAVKNRTYR KGVKSSRKER 

       550        560 
VCQTEFGGLT YFGTAKDAFT STLPTH 

« Hide

References

« Hide 'large scale' references
[1]"The complete sequence of a 11,953 bp fragment from C1G on chromosome III encompasses four new open reading frames."
Rad M.R., Luetzenkirchen K., Xu G., Kleinhans U., Hollenberg C.P.
Yeast 7:533-538(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete DNA sequence of yeast chromosome III."
Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M. expand/collapse author list , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components."
Estruch F., Cole C.N.
Mol. Biol. Cell 14:1664-1676(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION, FUNCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X59720 Genomic DNA. Translation: CAA42380.1.
BK006937 Genomic DNA. Translation: DAA07448.1.
PIRS17477.
RefSeqNP_009894.1. NM_001178681.1.

3D structure databases

ProteinModelPortalP25370.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid30947. 14 interactions.
DIPDIP-2955N.
MINTMINT-2733307.
STRING4932.YCL036W.

Proteomic databases

MaxQBP25370.
PaxDbP25370.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYCL036W; YCL036W; YCL036W.
GeneID850321.
KEGGsce:YCL036W.

Organism-specific databases

CYGDYCL036w.
SGDS000000541. GFD2.

Phylogenomic databases

eggNOGNOG260195.
GeneTreeENSGT00530000066839.
OMATHINGMR.
OrthoDBEOG7FZ08N.

Enzyme and pathway databases

BioCycYEAST:G3O-29295-MONOMER.

Gene expression databases

GenevestigatorP25370.

Family and domain databases

Gene3D3.30.420.10. 1 hit.
InterProIPR012337. RNaseH-like_dom.
[Graphical view]
SUPFAMSSF53098. SSF53098. 1 hit.
ProtoNetSearch...

Other

NextBio965733.

Entry information

Entry nameGFD2_YEAST
AccessionPrimary (citable) accession number: P25370
Secondary accession number(s): D6VQX9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome III

Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD