Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Inorganic phosphate transporter PHO87

Gene

PHO87

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the uptake of inorganic phosphate.

GO - Molecular functioni

  • inorganic phosphate transmembrane transporter activity Source: SGD

GO - Biological processi

  • phosphate ion transport Source: SGD
  • plasma membrane selenite transport Source: SGD
  • polyphosphate metabolic process Source: SGD
  • regulation of phosphate transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29349-MONOMER.
BRENDAi3.6.3.27. 984.

Protein family/group databases

TCDBi2.A.47.2.1. the divalent anion:na(+) symporter (dass) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inorganic phosphate transporter PHO87
Gene namesi
Name:PHO87
Ordered Locus Names:YCR037C
ORF Names:YCR37C, YCR524
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCR037C.
SGDiS000000633. PHO87.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 461461ExtracellularSequence analysisAdd
BLAST
Transmembranei462 – 48221HelicalSequence analysisAdd
BLAST
Topological domaini483 – 49311CytoplasmicSequence analysisAdd
BLAST
Transmembranei494 – 51421HelicalSequence analysisAdd
BLAST
Topological domaini515 – 53723ExtracellularSequence analysisAdd
BLAST
Transmembranei538 – 55821HelicalSequence analysisAdd
BLAST
Topological domaini559 – 58325CytoplasmicSequence analysisAdd
BLAST
Transmembranei584 – 60421HelicalSequence analysisAdd
BLAST
Topological domaini605 – 62723ExtracellularSequence analysisAdd
BLAST
Transmembranei628 – 64821HelicalSequence analysisAdd
BLAST
Topological domaini649 – 66719CytoplasmicSequence analysisAdd
BLAST
Transmembranei668 – 68821HelicalSequence analysisAdd
BLAST
Topological domaini689 – 70719ExtracellularSequence analysisAdd
BLAST
Transmembranei708 – 72821HelicalSequence analysisAdd
BLAST
Topological domaini729 – 7357CytoplasmicSequence analysis
Transmembranei736 – 75621HelicalSequence analysisAdd
BLAST
Topological domaini757 – 76711ExtracellularSequence analysisAdd
BLAST
Transmembranei768 – 78821HelicalSequence analysisAdd
BLAST
Topological domaini789 – 80214CytoplasmicSequence analysisAdd
BLAST
Transmembranei803 – 82321HelicalSequence analysisAdd
BLAST
Topological domaini824 – 84926ExtracellularSequence analysisAdd
BLAST
Transmembranei850 – 87021HelicalSequence analysisAdd
BLAST
Topological domaini871 – 89828CytoplasmicSequence analysisAdd
BLAST
Transmembranei899 – 91921HelicalSequence analysisAdd
BLAST
Topological domaini920 – 9234ExtracellularSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 923923Inorganic phosphate transporter PHO87PRO_0000172517Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki102 – 102Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)Combined sources1 Publication
Glycosylationi162 – 1621N-linked (GlcNAc...)Sequence analysis
Glycosylationi202 – 2021N-linked (GlcNAc...)Sequence analysis
Glycosylationi274 – 2741N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein, Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQBiP25360.
PRIDEiP25360.

PTM databases

iPTMnetiP25360.

Interactioni

Protein-protein interaction databases

BioGridi31020. 59 interactions.
DIPiDIP-7842N.
IntActiP25360. 6 interactions.
MINTiMINT-1362346.

Structurei

3D structure databases

ProteinModelPortaliP25360.
SMRiP25360. Positions 481-894.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 334334SPXPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SPX domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00730000112809.
HOGENOMiHOG000211490.
InParanoidiP25360.
KOiK14430.
OMAiFANAFCG.
OrthoDBiEOG092C0UFE.

Family and domain databases

InterProiIPR004680. Cit_transptr-like_dom.
IPR004331. SPX_dom.
[Graphical view]
PfamiPF03600. CitMHS. 1 hit.
PF03105. SPX. 1 hit.
[Graphical view]
PROSITEiPS51382. SPX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P25360-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFSHFLKYN AVPEWQNHYL DYNELKNLIY TLQTDELKQE TPTGDLNDDA
60 70 80 90 100
DSQTPGPIAD IESNIAAGEP SSSKRRFTHK LKRKLFGSKT PSGSKRGDSD
110 120 130 140 150
EKAIDGNNIN EETIELDELS PQGKTTSFNK NFIRKKFFES RSSSVSSEGK
160 170 180 190 200
TLFSSYDTFV TNLSDEKLKV DDFYKRMEAK FYERFDHLIN DLEKEGIVTR
210 220 230 240 250
LNETFNPEIQ ALPPLREIIS GTSETHSSNN PFEIHSSNID SELRNRFDYS
260 270 280 290 300
EEEMDEDDDV DVFADTTDNT ALLNYSQFNI KSQKKSLLKQ TIINLYIDLC
310 320 330 340 350
QLKSFIELNR MGFSKITKKS DKVLHMNTRQ ELIESEEFFK DTYIFQHETL
360 370 380 390 400
SSLNSKIAQL IEFYAVLMGQ PGNVDSCKQE LKSYLHDHIV WERSNTWKDM
410 420 430 440 450
LGLSSQNNDI ITIEDEAEKL MQEKLQIEYF KYPLPKPINL KFTKIENLAV
460 470 480 490 500
PKLFFGKRAM KIGFIIIVTG VLLGVKTFND PVEHRCMALV ECCAFLWASE
510 520 530 540 550
AIPLHITGLL VPLLTVLFRV LKDDDGKVMG AAAASTEILG TMWSSTIMIL
560 570 580 590 600
LAGFTLGEAL SQYNVAKVLA SWLLALAGTK PRNVLLMAMS VVFFLSMWIS
610 620 630 640 650
NVASPVLTYS LLTPLLDPLD YTSPFAKALV MGVALSADIG GMASPISSPQ
660 670 680 690 700
NIISMQYLKP YGIGWGQFFA VALPTGILSM LCSWALMILT FKIGKTKLEK
710 720 730 740 750
FKPIRTRFTI KQYFIIIVTI ATILLWCVES QIESAFGSSG EIAVIPIVLF
760 770 780 790 800
FGTGLLSTKD FNTFPWSIVV LAMGGIALGK AVSSSGLLVT IARALQKKIQ
810 820 830 840 850
NDGVFAILCI FGILMLVVGT FVSHTVSAII IIPLVQEVGD KLSDPKAAPI
860 870 880 890 900
LVFGCALLAS CGMGLASSGF PNVTAISMTD KKGNRWLTVG AFISRGVPAS
910 920
LLAFVCVITL GYGISSSVLK GST
Length:923
Mass (Da):102,540
Last modified:March 15, 2004 - v2
Checksum:iE94DC4C152355A47
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti72 – 721S → P in CAA40229 (PubMed:1964349).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56909 Genomic DNA. Translation: CAA40229.1.
X59720 Genomic DNA. Translation: CAA42304.2.
BK006937 Genomic DNA. Translation: DAA07516.1.
PIRiS12919. MMBY7C.
RefSeqiNP_009966.2. NM_001178751.1.

Genome annotation databases

EnsemblFungiiCAA42304; CAA42304; CAA42304.
YCR037C; YCR037C; YCR037C.
GeneIDi850403.
KEGGisce:YCR037C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56909 Genomic DNA. Translation: CAA40229.1.
X59720 Genomic DNA. Translation: CAA42304.2.
BK006937 Genomic DNA. Translation: DAA07516.1.
PIRiS12919. MMBY7C.
RefSeqiNP_009966.2. NM_001178751.1.

3D structure databases

ProteinModelPortaliP25360.
SMRiP25360. Positions 481-894.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31020. 59 interactions.
DIPiDIP-7842N.
IntActiP25360. 6 interactions.
MINTiMINT-1362346.

Protein family/group databases

TCDBi2.A.47.2.1. the divalent anion:na(+) symporter (dass) family.

PTM databases

iPTMnetiP25360.

Proteomic databases

MaxQBiP25360.
PRIDEiP25360.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAA42304; CAA42304; CAA42304.
YCR037C; YCR037C; YCR037C.
GeneIDi850403.
KEGGisce:YCR037C.

Organism-specific databases

EuPathDBiFungiDB:YCR037C.
SGDiS000000633. PHO87.

Phylogenomic databases

GeneTreeiENSGT00730000112809.
HOGENOMiHOG000211490.
InParanoidiP25360.
KOiK14430.
OMAiFANAFCG.
OrthoDBiEOG092C0UFE.

Enzyme and pathway databases

BioCyciYEAST:G3O-29349-MONOMER.
BRENDAi3.6.3.27. 984.

Miscellaneous databases

PROiP25360.

Family and domain databases

InterProiIPR004680. Cit_transptr-like_dom.
IPR004331. SPX_dom.
[Graphical view]
PfamiPF03600. CitMHS. 1 hit.
PF03105. SPX. 1 hit.
[Graphical view]
PROSITEiPS51382. SPX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPHO87_YEAST
AccessioniPrimary (citable) accession number: P25360
Secondary accession number(s): D6VR47
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: March 15, 2004
Last modified: September 7, 2016
This is version 146 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 504 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.