Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable DNA-binding protein SNT1

Gene

SNT1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis.

Miscellaneous

Present with 396 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi911 – 934H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

  • DNA binding Source: UniProtKB
  • RNA polymerase II transcription coactivator activity Source: GO_Central

GO - Biological processi

  • histone deacetylation Source: UniProtKB
  • negative regulation of meiotic nuclear division Source: UniProtKB
  • positive regulation of stress-activated MAPK cascade Source: SGD
  • regulation of transcription, DNA-templated Source: SGD
  • regulation of transcription from RNA polymerase II promoter Source: GO_Central

Keywordsi

Molecular functionDNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-29347-MONOMER.
ReactomeiR-SCE-3214815. HDACs deacetylate histones.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA-binding protein SNT1
Alternative name(s):
SANT domain-containing protein 1
Gene namesi
Name:SNT1
Ordered Locus Names:YCR033W
ORF Names:YCR33W, YCR592
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCR033W.
SGDiS000000629. SNT1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001971221 – 1226Probable DNA-binding protein SNT1Add BLAST1226

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei187PhosphoserineCombined sources1
Modified residuei395PhosphoserineCombined sources1
Modified residuei796PhosphothreonineCombined sources1
Modified residuei1037PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP25357.
PRIDEiP25357.

PTM databases

iPTMnetiP25357.

Interactioni

Subunit structurei

Identified in a Set3C complex with SET3, HST1, HOS2, SIF2, CPR1 and HOS4.1 Publication

Protein-protein interaction databases

BioGridi31016. 630 interactors.
DIPiDIP-2082N.
IntActiP25357. 14 interactors.
MINTiMINT-495459.
STRINGi4932.YCR033W.

Structurei

3D structure databases

ProteinModelPortaliP25357.
SMRiP25357.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini668 – 720SANTPROSITE-ProRule annotationAdd BLAST53
Domaini884 – 938HTH myb-typePROSITE-ProRule annotationAdd BLAST55

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili539 – 591Sequence analysisAdd BLAST53

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi28 – 159Ser-richAdd BLAST132
Compositional biasi594 – 599Poly-Ser6

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

GeneTreeiENSGT00840000129748.
InParanoidiP25357.
OMAiTFAHTAT.
OrthoDBiEOG092C0RC3.

Family and domain databases

CDDicd00167. SANT. 2 hits.
InterProiView protein in InterPro
IPR009057. Homeobox-like_sf.
IPR017930. Myb_dom.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
PfamiView protein in Pfam
PF00249. Myb_DNA-binding. 2 hits.
SMARTiView protein in SMART
SM00717. SANT. 2 hits.
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiView protein in PROSITE
PS51294. HTH_MYB. 1 hit.
PS51293. SANT. 1 hit.

Sequencei

Sequence statusi: Complete.

P25357-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGYPPPTRRL GDKKRYHYSN NPNRRHPSAV YSKNSFPKSS NNGFVSSPTA
60 70 80 90 100
DNSTNPSVTP STASVPLPTA APGSTFGIEA PRPSRYDPSS VSRPSSSSYS
110 120 130 140 150
STRKIGSRYN PDVERSSSTT SSTPESMNTS TITHTNTDIG NSRYSRKTMS
160 170 180 190 200
RYNPQSTSST NVTHFPSALS NAPPFYVANG SSRRPRSMDD YSPDVTNKLE
210 220 230 240 250
TNNVSSVNNN SPHSYYSRSN KWRSIGTPSR PPFDNHVGNM TTTSNTNSIH
260 270 280 290 300
QREPFWKANS TTILKSTHSQ SSPSLHTKKF HDANKLDKPE ASVKVETPSK
310 320 330 340 350
DETKAISYHD NNFPPRKSVS KPNAPLEPDN IKVGEEDALG KKEVHKSGRE
360 370 380 390 400
IAKEHPTPVK MKEHDELEAR AKKVSKINID GKQDEIWTTA KTVASAVEVS
410 420 430 440 450
KESQKELTRS VERKESPEIR DYERAYDPKA LKTDVTKLTV DNDNKSYEEP
460 470 480 490 500
LEKVEGCIFP LPKAETRLWE LKNQKRNKII SEQKYLLKKA IRNFSEYPFY
510 520 530 540 550
AQNKLIHQQA TGLILTKIIS KIKKEEHLKK INLKHDYFDL QKKYEKECEI
560 570 580 590 600
LTKLSENLRK EEIENKRKEH ELMEQKRREE GIETEKEKSL RHPSSSSSSR
610 620 630 640 650
RRNRADFVDD AEMENVLLQI DPNYKHYQAA ATIPPLILDP IRKHSYKFCD
660 670 680 690 700
VNNLVTDKKL WASRILKDAS DNFTDHEHSL FLEGYLIHPK KFGKISHYMG
710 720 730 740 750
GLRSPEECVL HYYRTKKTVN YKQLLIDKNK KRKMSAAAKR RKRKERSNDE
760 770 780 790 800
EVEVDESKEE STNTIEKEEK SENNAEENVQ PVLVQGSEVK GDPLGTPEKV
810 820 830 840 850
ENMIEQRGEE FAGELENAER VNDLKRAHDE VGEESNKSSV IETNNGVQIM
860 870 880 890 900
DPKGAVQNGY YPEETKELDF SLENALQRKK HKSAPEHKTS YWSVRESQLF
910 920 930 940 950
PELLKEFGSQ WSLISEKLGT KSTTMVRNYY QRNAARNGWK LLVDETDLKR
960 970 980 990 1000
DGTSSESVQQ SQILIQPERP NINAYSNIPP QQRPALGYFV GQPTHGHNTS
1010 1020 1030 1040 1050
ISSIDGSIRP FGPDFHRDTF SKISAPLTTL PPPRLPSIQF PRSEMAEPTV
1060 1070 1080 1090 1100
TDLRNRPLDH IDTLADAASS VTNNQNFSNE RNAIDIGRKS TTISNLLNNS
1110 1120 1130 1140 1150
DRSMKSSFQS ASRHEAQLED TPSMNNIVVQ EIKPNITTPR SSSISALLNP
1160 1170 1180 1190 1200
VNGNGQSNPD GRPLLPFQHA ISQGTPTFPL PAPRTSPISR APPKFNFSND
1210 1220
PLAALAAVAS APDAMSSFLS KKENNN
Length:1,226
Mass (Da):138,397
Last modified:June 27, 2003 - v2
Checksum:i70AE6622227088EB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti305A → T in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti375S → N in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti404Q → H in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti435V → A in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti442N → D in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti482E → K in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti513L → V in AAB21259 (PubMed:1776366).Curated1
Sequence conflicti644H → Y in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti766E → D in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti806Q → K in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti831V → I in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti846G → E in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti851D → A in CAA41799 (PubMed:1872032).Curated1
Sequence conflicti855 – 857AVQ → GVR in CAA41799 (PubMed:1872032).Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S78624 Genomic DNA. Translation: AAB21259.1.
X59075 Genomic DNA. Translation: CAA41799.1.
X59720 Genomic DNA. Translation: CAC42983.1.
BK006937 Genomic DNA. Translation: DAA07512.1.
PIRiS15053.
RefSeqiNP_009962.2. NM_001178747.1.

Genome annotation databases

EnsemblFungiiCAC42983; CAC42983; CAC42983.
YCR033W; YCR033W; YCR033W.
GeneIDi850399.
KEGGisce:YCR033W.

Similar proteinsi

Entry informationi

Entry nameiSNT1_YEAST
AccessioniPrimary (citable) accession number: P25357
Secondary accession number(s): D6VR43, Q02397, Q8NIL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: June 27, 2003
Last modified: November 22, 2017
This is version 153 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names