Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P25355 (CTR86_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Copper transport protein 86
Gene names
Name:CTR86
Ordered Locus Names:YCR054C
ORF Names:YCR54C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Essential protein which may be involved in threonine biosynthesis.

Subcellular location

Cytoplasm Ref.4.

Miscellaneous

Present with 8970 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the CTR86 family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Threonine biosynthesis
   Cellular componentCytoplasm
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processthreonine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 563563Copper transport protein 86
PRO_0000202572

Amino acid modifications

Modified residue4331Phosphothreonine Ref.6
Modified residue5591Phosphoserine Ref.6 Ref.7

Sequences

Sequence LengthMass (Da)Tools
P25355 [UniParc].

Last modified May 1, 1992. Version 1.
Checksum: 38DE4EBFA781D629

FASTA56365,206
        10         20         30         40         50         60 
MPMNNFLDEF NLFDSIITMM KNDPCCVEDY EPIVENLNRI FQRTFNDEEH RKSMANSQLF 

        70         80         90        100        110        120 
WERLRDTLEA MLLPASLNEN SSIPYTRTVR GLILMMRNLA AENQEIPQKL LLQNLVIRGF 

       130        140        150        160        170        180 
LHATSEYVVD TPLIKHLYIA CLTCLFNIQQ NYSTVDMTTF PALLQFLQYP YGIKLEDGEE 

       190        200        210        220        230        240 
EEHFWLPYLF LFKTYLNNDE FSNEFFRDND TPQKDYYCVR DRIFFDIVTA KFIQDQENSF 

       250        260        270        280        290        300 
LIEKGRNYLD DSKLEITSID LSVLECISKS LTTASFGKYL NGLEERQPGK FTTLLQILQL 

       310        320        330        340        350        360 
VVTSKEDWNT YELTAIMSWC YPILQRLACK DIPAFFNKSC NDYAPSVAIQ LHSTLLSCLD 

       370        380        390        400        410        420 
IISDLCKFNH VRKFLISYDS VKILVSLLDT FQKNLLRINF LKGNGDTVNE IKITDHEGNK 

       430        440        450        460        470        480 
IEDRLLIFNR VNTNESFIRA DNFPHCKLVI IEILASLVYA HPEIQDQIRE LGGLALILSN 

       490        500        510        520        530        540 
CVIDDNDPFI KERSIVCLKF LLKNNAKNQE YVKKMEAQDV VQDDALSKAG FEISVEKGGK 

       550        560 
VRLVSKEEDP GNENSEIISI DED 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the THR4 region on chromosome III of the yeast Saccharomyces cerevisiae."
Mannhaupt G., van der Linden C.G., Vetter I., Maurer K., Pilz U., Planta R.J., Feldmann H.
Yeast 6:353-361(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete DNA sequence of yeast chromosome III."
Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M. expand/collapse author list , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-433 AND SER-559, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-559, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X59720 Genomic DNA. Translation: CAA42285.1.
BK006937 Genomic DNA. Translation: DAA07531.1.
PIRS22837.
RefSeqNP_009983.1. NM_001178768.1.

3D structure databases

ProteinModelPortalP25355.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31034. 2 interactions.
DIPDIP-2728N.
IntActP25355. 8 interactions.
MINTMINT-1625390.
STRING4932.YCR054C.

Proteomic databases

PaxDbP25355.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYCR054C; YCR054C; YCR054C.
GeneID850421.
KEGGsce:YCR054C.

Organism-specific databases

CYGDYCR054c.
SGDS000000650. CTR86.

Phylogenomic databases

eggNOGNOG330117.
GeneTreeENSGT00390000010377.
HOGENOMHOG000000904.
OMAPFIKERS.
OrthoDBEOG7GN2WV.

Enzyme and pathway databases

BioCycYEAST:G3O-29362-MONOMER.

Gene expression databases

GenevestigatorP25355.

Family and domain databases

Gene3D1.25.10.10. 4 hits.
InterProIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR019156. Ataxin-10_domain.
[Graphical view]
PfamPF09759. Atx10homo_assoc. 1 hit.
[Graphical view]
SUPFAMSSF48371. SSF48371. 2 hits.
ProtoNetSearch...

Other

NextBio965989.
PROP25355.

Entry information

Entry nameCTR86_YEAST
AccessionPrimary (citable) accession number: P25355
Secondary accession number(s): D6VR62
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: March 19, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome III

Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families