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Protein

Uncharacterized membrane protein YCR023C

Gene

YCR023C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29338-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized membrane protein YCR023C
Gene namesi
Ordered Locus Names:YCR023C
ORF Names:YCR23C, YCR241
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCR023C.
SGDiS000000617. YCR023C.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 89ExtracellularSequence analysisAdd BLAST89
Transmembranei90 – 110HelicalSequence analysisAdd BLAST21
Topological domaini111 – 152CytoplasmicSequence analysisAdd BLAST42
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21
Topological domaini174 – 199ExtracellularSequence analysisAdd BLAST26
Transmembranei200 – 220HelicalSequence analysisAdd BLAST21
Topological domaini221 – 353CytoplasmicSequence analysisAdd BLAST133
Transmembranei354 – 372HelicalSequence analysisAdd BLAST19
Topological domaini373 – 413ExtracellularSequence analysisAdd BLAST41
Transmembranei414 – 434HelicalSequence analysisAdd BLAST21
Topological domaini435 – 442CytoplasmicSequence analysis8
Transmembranei443 – 463HelicalSequence analysisAdd BLAST21
Topological domaini464 – 542ExtracellularSequence analysisAdd BLAST79
Transmembranei543 – 563HelicalSequence analysisAdd BLAST21
Topological domaini564 – 611CytoplasmicSequence analysisAdd BLAST48

GO - Cellular componenti

  • fungal-type vacuole membrane Source: SGD
  • integral component of membrane Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001734251 – 611Uncharacterized membrane protein YCR023CAdd BLAST611

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei313PhosphoserineCombined sources1
Modified residuei603PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP25351.

PTM databases

iPTMnetiP25351.

Interactioni

Protein-protein interaction databases

BioGridi31005. 8 interactors.
DIPiDIP-1960N.

Structurei

3D structure databases

ProteinModelPortaliP25351.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000246660.
InParanoidiP25351.
OMAiHECNASE.
OrthoDBiEOG092C255V.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P25351-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARQKLTFKE QMDGFPWVQL VVVSLVRFSE PIAFSSLFPY VYFMVRDFNI
60 70 80 90 100
APNDAQVSKY SGYLSSSFAL CQVISAYHWG RFSEKHGRKI TLTCGLIGTS
110 120 130 140 150
VSLLILGFSR NFYQALVARS LMGLLNGNVG VIRTIIGEIA TERKHQALAF
160 170 180 190 200
STMPLLFQFG AVVGPMIGGF LVFRDGTMNE VPLWFPHFAK RIIRSYPYAL
210 220 230 240 250
PNVVVCMFLM FGLTNATLFL EETHPAFKDR RDYGLEVGDF IKKNIFGIQP
260 270 280 290 300
KRRPWQKRIQ DDSENIHHRN ENVNSIRGQD SEEDENSPLV NTTNDDDTES
310 320 330 340 350
IQSIDPILTR RQSVGLIRTY SLHEPTDAVH ANIDTAPDGC KESSIFHHVF
360 370 380 390 400
HTKVFYPISV NFIMALHLIV YNEFLPVFLA YDLAVDPENP KKLASKFPWK
410 420 430 440 450
ISGGIGYEPE QTGTLLSTTG IFGCFVVIFI FPIVDRNFDC LTIFRTLVKL
460 470 480 490 500
YPIMYVMVPY VVFLQNERIP SWYTVVYLYI ITGIKTFCGA LTSPQIMLLI
510 520 530 540 550
HNSSPLSCRS VINGATISIS ASARFIGPLV WGYIMSWSQQ NDVAWVSWWS
560 570 580 590 600
LSLFCMVALY QSYKIAPIDD NENELHGQGS EDAYNSQSQS SDLRMAHRSS
610
LSSLSNQRCT T
Length:611
Mass (Da):69,218
Last modified:May 16, 2003 - v2
Checksum:i1BD182315B11E7B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAC42975.1.
BK006937 Genomic DNA. Translation: DAA07501.1.
PIRiS19434.
RefSeqiNP_009952.2. NM_001178737.1.

Genome annotation databases

EnsemblFungiiCAC42975; CAC42975; CAC42975.
YCR023C; YCR023C; YCR023C.
GeneIDi850387.
KEGGisce:YCR023C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAC42975.1.
BK006937 Genomic DNA. Translation: DAA07501.1.
PIRiS19434.
RefSeqiNP_009952.2. NM_001178737.1.

3D structure databases

ProteinModelPortaliP25351.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31005. 8 interactors.
DIPiDIP-1960N.

PTM databases

iPTMnetiP25351.

Proteomic databases

PRIDEiP25351.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAC42975; CAC42975; CAC42975.
YCR023C; YCR023C; YCR023C.
GeneIDi850387.
KEGGisce:YCR023C.

Organism-specific databases

EuPathDBiFungiDB:YCR023C.
SGDiS000000617. YCR023C.

Phylogenomic databases

HOGENOMiHOG000246660.
InParanoidiP25351.
OMAiHECNASE.
OrthoDBiEOG092C255V.

Enzyme and pathway databases

BioCyciYEAST:G3O-29338-MONOMER.

Miscellaneous databases

PROiP25351.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYCR3_YEAST
AccessioniPrimary (citable) accession number: P25351
Secondary accession number(s): D6VR32, Q8NKJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 16, 2003
Last modified: November 2, 2016
This is version 132 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.