Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable metabolite transport protein GIT1

Gene

GIT1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • glycerol-3-phosphate transmembrane transporter activity Source: SGD
  • glycerophosphodiester transmembrane transporter activity Source: SGD

GO - Biological processi

  • glycerol-3-phosphate transport Source: SGD
  • glycerophosphodiester transport Source: SGD
  • transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-29392-MONOMER.

Protein family/group databases

TCDBi2.A.1.9.7. the major facilitator superfamily (mfs).

Chemistry databases

SwissLipidsiSLP:000000076.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable metabolite transport protein GIT1
Gene namesi
Name:GIT1
Ordered Locus Names:YCR098C
ORF Names:YCR137, YCR98C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCR098C.
SGDiS000000695. GIT1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 44CytoplasmicSequence analysisAdd BLAST44
Transmembranei45 – 65Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini66 – 91ExtracellularSequence analysisAdd BLAST26
Transmembranei92 – 112Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini113 – 114CytoplasmicSequence analysis2
Transmembranei115 – 136Helical; Name=3Sequence analysisAdd BLAST22
Topological domaini137 – 138ExtracellularSequence analysis2
Transmembranei139 – 159Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini160 – 184CytoplasmicSequence analysisAdd BLAST25
Transmembranei185 – 205Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini206 – 216ExtracellularSequence analysisAdd BLAST11
Transmembranei217 – 237Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini238 – 268CytoplasmicSequence analysisAdd BLAST31
Transmembranei269 – 289Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini290 – 306ExtracellularSequence analysisAdd BLAST17
Transmembranei307 – 327Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini328 – 335CytoplasmicSequence analysis8
Transmembranei336 – 356Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini357 – 360ExtracellularSequence analysis4
Transmembranei361 – 381Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini382 – 399CytoplasmicSequence analysisAdd BLAST18
Transmembranei400 – 420Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini421 – 430ExtracellularSequence analysis10
Transmembranei431 – 451Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini452 – 518CytoplasmicSequence analysisAdd BLAST67

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504591 – 518Probable metabolite transport protein GIT1Add BLAST518

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi80N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiP25346.
TopDownProteomicsiP25346.

PTM databases

iPTMnetiP25346.

Interactioni

Protein-protein interaction databases

BioGridi31071. 14 interactors.
DIPiDIP-4626N.
IntActiP25346. 3 interactors.
MINTiMINT-546964.

Structurei

3D structure databases

ProteinModelPortaliP25346.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000214987.
InParanoidiP25346.
OMAiLMTMSNV.
OrthoDBiEOG092C241Y.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P25346-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDKDITSVN EKEVNENTNP RIIKYDAERR ATRTETSKKD KWKNIVTIIA
60 70 80 90 100
SGFALISDGY VNGSMSMLNK VFVMEYGKKN YSSKVSTRVS NAALVGIIFG
110 120 130 140 150
QFFMGIAADY YSRKSCILVA TAILVIGSAL CAASHGTTVP GMFWMLTVMR
160 170 180 190 200
GLVGIGVGAE YPTSTLSANE SANEYTTTKR GGILVMVTNL PLAFGGPFAT
210 220 230 240 250
IIFLIVYKIC SGTKHLEAIW RTVFAIGCFW PLSVFYFRWK TATTEVYEKG
260 270 280 290 300
RIKRNIPYFL ALKFYWKRLL GTCGTWFMYD FVTFPNGIFS STIISSVIKD
310 320 330 340 350
QNDLVKVAEW NLLLGVLAVL GVPIGAYLSD RIGRKYTLMF GFSGYIIFGL
360 370 380 390 400
IIGCAYDQLK KITPLFIIFY AFMNMLGNAG PGDMLGVISS EASATAVRGV
410 420 430 440 450
FYGLSAVTGK IGSVVGVECF QPIRDNLGAR WTFIIAAICG LIGIIITYFF
460 470 480 490 500
VPHSLESDLM KQDVEFHNYL VSNGWTGKMG FDETDEESMV RTIEVEENGT
510
NCSKKNAEII SVRQVDQS
Length:518
Mass (Da):57,322
Last modified:May 1, 1992 - v1
Checksum:iD173B1B0096F4D0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42240.1.
BK006937 Genomic DNA. Translation: DAA07568.1.
PIRiS19514.
RefSeqiNP_010022.1. NM_001178805.1.

Genome annotation databases

EnsemblFungiiCAA42240; CAA42240; CAA42240.
YCR098C; YCR098C; YCR098C.
GeneIDi850462.
KEGGisce:YCR098C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42240.1.
BK006937 Genomic DNA. Translation: DAA07568.1.
PIRiS19514.
RefSeqiNP_010022.1. NM_001178805.1.

3D structure databases

ProteinModelPortaliP25346.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31071. 14 interactors.
DIPiDIP-4626N.
IntActiP25346. 3 interactors.
MINTiMINT-546964.

Chemistry databases

SwissLipidsiSLP:000000076.

Protein family/group databases

TCDBi2.A.1.9.7. the major facilitator superfamily (mfs).

PTM databases

iPTMnetiP25346.

Proteomic databases

PRIDEiP25346.
TopDownProteomicsiP25346.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAA42240; CAA42240; CAA42240.
YCR098C; YCR098C; YCR098C.
GeneIDi850462.
KEGGisce:YCR098C.

Organism-specific databases

EuPathDBiFungiDB:YCR098C.
SGDiS000000695. GIT1.

Phylogenomic databases

HOGENOMiHOG000214987.
InParanoidiP25346.
OMAiLMTMSNV.
OrthoDBiEOG092C241Y.

Enzyme and pathway databases

BioCyciYEAST:G3O-29392-MONOMER.

Miscellaneous databases

PROiP25346.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGIT1_YEAST
AccessioniPrimary (citable) accession number: P25346
Secondary accession number(s): D6VR99
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: November 30, 2016
This is version 139 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.