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Protein

Reduced viability upon starvation protein 161

Gene

RVS161

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of a cytoskeletal structure that is required for the formation of endocytic vesicles at the plasma membrane level.

Miscellaneous

Mutations in this gene results in sensitivity to carbon, nitrogen and sulfur starvation.
Present with 7390 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • cytoskeletal protein binding Source: SGD

GO - Biological processi

  • actin cortical patch localization Source: SGD
  • actin cytoskeleton organization Source: SGD
  • actin cytoskeleton reorganization Source: SGD
  • actin filament organization Source: InterPro
  • conjugation with cellular fusion Source: SGD
  • endocytosis Source: SGD
  • lipid tube assembly Source: SGD
  • plasma membrane tubulation Source: SGD
  • response to osmotic stress Source: SGD
  • response to starvation Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-29326-MONOMER

Protein family/group databases

TCDBi8.A.34.2.1 the endophilin (endophilin) family

Names & Taxonomyi

Protein namesi
Recommended name:
Reduced viability upon starvation protein 161
Gene namesi
Name:RVS161
Synonyms:END6, SPE161
Ordered Locus Names:YCR009C
ORF Names:YCR9C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi

Organism-specific databases

EuPathDBiFungiDB:YCR009C
SGDiS000000602 RVS161

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001929601 – 265Reduced viability upon starvation protein 161Add BLAST265

Proteomic databases

MaxQBiP25343
PaxDbiP25343
PRIDEiP25343

PTM databases

iPTMnetiP25343

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
RVS167P3974316EBI-14490,EBI-14500

GO - Molecular functioni

  • cytoskeletal protein binding Source: SGD

Protein-protein interaction databases

BioGridi30988, 969 interactors
DIPiDIP-1601N
IntActiP25343, 49 interactors
MINTiP25343
STRINGi4932.YCR009C

Structurei

3D structure databases

ProteinModelPortaliP25343
SMRiP25343
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 239BARPROSITE-ProRule annotationAdd BLAST225

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili126 – 193Sequence analysisAdd BLAST68

Keywords - Domaini

Coiled coil

Phylogenomic databases

GeneTreeiENSGT00510000048076
HOGENOMiHOG000172086
InParanoidiP25343
KOiK20120
OMAiNDRDYEV
OrthoDBiEOG092C3S3O

Family and domain databases

CDDicd07591 BAR_Rvs161p, 1 hit
Gene3Di1.20.1270.60, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR004148 BAR_dom
IPR037429 Rvs161/Hob3_BAR
PfamiView protein in Pfam
PF03114 BAR, 1 hit
SMARTiView protein in SMART
SM00721 BAR, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
PROSITEiView protein in PROSITE
PS51021 BAR, 1 hit

Sequencei

Sequence statusi: Complete.

P25343-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWEGFKKAI NRAGHSVIIK NVDKTIDKEY DMEERRYKVL QRAGEALQKE
60 70 80 90 100
AKGFLDSLRA VTASQTTIAE VISNLYDDSK YVAGGGYNVG NYYLQCVQDF
110 120 130 140 150
DSETVKQLDG PLRETVLDPI TKFSTYFKEI EEAIKKRDHK KQDFDAAKAK
160 170 180 190 200
VRRLVDKPAK DASKLPRAEK ELSLAKDIFE NLNNQLKTEL PQLVSLRVPY
210 220 230 240 250
FDPSFEALIK IQLRFCTDGY TRLAQIQQYL DQQSRDDYAN GLLDTKIEEL
260
LGQMTSLDIC ALGIK
Length:265
Mass (Da):30,250
Last modified:May 1, 1992 - v1
Checksum:iB35EA00E0C900E2D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti95Q → E in CAA44926 (PubMed:2183524).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63315 Genomic DNA Translation: CAA44926.1
X59720 Genomic DNA Translation: CAA42326.1
BK006937 Genomic DNA Translation: DAA07487.1
PIRiS19516
RefSeqiNP_009935.1, NM_001178722.1

Genome annotation databases

EnsemblFungiiCAA42326; CAA42326; CAA42326
YCR009C; YCR009C; YCR009C
GeneIDi850367
KEGGisce:YCR009C

Similar proteinsi

Entry informationi

Entry nameiRV161_YEAST
AccessioniPrimary (citable) accession number: P25343
Secondary accession number(s): D6VR18
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: May 23, 2018
This is version 150 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

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