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Protein

Reduced viability upon starvation protein 161

Gene

RVS161

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of a cytoskeletal structure that is required for the formation of endocytic vesicles at the plasma membrane level.

GO - Molecular functioni

  • cytoskeletal protein binding Source: SGD

GO - Biological processi

  • actin cortical patch localization Source: SGD
  • actin cytoskeleton organization Source: SGD
  • actin cytoskeleton reorganization Source: SGD
  • conjugation with cellular fusion Source: SGD
  • endocytosis Source: SGD
  • lipid tube assembly Source: SGD
  • membrane tubulation Source: SGD
  • response to osmotic stress Source: SGD
  • response to starvation Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29326-MONOMER.

Protein family/group databases

TCDBi8.A.34.2.1. the endophilin (endophilin) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Reduced viability upon starvation protein 161
Gene namesi
Name:RVS161
Synonyms:END6, SPE161
Ordered Locus Names:YCR009C
ORF Names:YCR9C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCR009C.
SGDiS000000602. RVS161.

Subcellular locationi

GO - Cellular componenti

  • actin cortical patch Source: SGD
  • mating projection Source: SGD
  • membrane raft Source: SGD
  • Rvs161p-Rvs167p complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265Reduced viability upon starvation protein 161PRO_0000192960Add
BLAST

Proteomic databases

MaxQBiP25343.

PTM databases

iPTMnetiP25343.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
RVS167P3974314EBI-14490,EBI-14500

GO - Molecular functioni

  • cytoskeletal protein binding Source: SGD

Protein-protein interaction databases

BioGridi30988. 439 interactions.
DIPiDIP-1601N.
IntActiP25343. 23 interactions.
MINTiMINT-370070.

Structurei

3D structure databases

ProteinModelPortaliP25343.
SMRiP25343. Positions 12-215.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 239225BARPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili126 – 19368Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 BAR domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

GeneTreeiENSGT00510000048076.
HOGENOMiHOG000172086.
InParanoidiP25343.
KOiK20120.
OMAiIPPENEN.
OrthoDBiEOG092C3S3O.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR004148. BAR_dom.
[Graphical view]
PfamiPF03114. BAR. 1 hit.
[Graphical view]
SMARTiSM00721. BAR. 1 hit.
[Graphical view]
PROSITEiPS51021. BAR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P25343-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWEGFKKAI NRAGHSVIIK NVDKTIDKEY DMEERRYKVL QRAGEALQKE
60 70 80 90 100
AKGFLDSLRA VTASQTTIAE VISNLYDDSK YVAGGGYNVG NYYLQCVQDF
110 120 130 140 150
DSETVKQLDG PLRETVLDPI TKFSTYFKEI EEAIKKRDHK KQDFDAAKAK
160 170 180 190 200
VRRLVDKPAK DASKLPRAEK ELSLAKDIFE NLNNQLKTEL PQLVSLRVPY
210 220 230 240 250
FDPSFEALIK IQLRFCTDGY TRLAQIQQYL DQQSRDDYAN GLLDTKIEEL
260
LGQMTSLDIC ALGIK
Length:265
Mass (Da):30,250
Last modified:May 1, 1992 - v1
Checksum:iB35EA00E0C900E2D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti95 – 951Q → E in CAA44926 (PubMed:2183524).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63315 Genomic DNA. Translation: CAA44926.1.
X59720 Genomic DNA. Translation: CAA42326.1.
BK006937 Genomic DNA. Translation: DAA07487.1.
PIRiS19516.
RefSeqiNP_009935.1. NM_001178722.1.

Genome annotation databases

EnsemblFungiiCAA42326; CAA42326; CAA42326.
YCR009C; YCR009C; YCR009C.
GeneIDi850367.
KEGGisce:YCR009C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63315 Genomic DNA. Translation: CAA44926.1.
X59720 Genomic DNA. Translation: CAA42326.1.
BK006937 Genomic DNA. Translation: DAA07487.1.
PIRiS19516.
RefSeqiNP_009935.1. NM_001178722.1.

3D structure databases

ProteinModelPortaliP25343.
SMRiP25343. Positions 12-215.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi30988. 439 interactions.
DIPiDIP-1601N.
IntActiP25343. 23 interactions.
MINTiMINT-370070.

Protein family/group databases

TCDBi8.A.34.2.1. the endophilin (endophilin) family.

PTM databases

iPTMnetiP25343.

Proteomic databases

MaxQBiP25343.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAA42326; CAA42326; CAA42326.
YCR009C; YCR009C; YCR009C.
GeneIDi850367.
KEGGisce:YCR009C.

Organism-specific databases

EuPathDBiFungiDB:YCR009C.
SGDiS000000602. RVS161.

Phylogenomic databases

GeneTreeiENSGT00510000048076.
HOGENOMiHOG000172086.
InParanoidiP25343.
KOiK20120.
OMAiIPPENEN.
OrthoDBiEOG092C3S3O.

Enzyme and pathway databases

BioCyciYEAST:G3O-29326-MONOMER.

Miscellaneous databases

PROiP25343.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR004148. BAR_dom.
[Graphical view]
PfamiPF03114. BAR. 1 hit.
[Graphical view]
SMARTiSM00721. BAR. 1 hit.
[Graphical view]
PROSITEiPS51021. BAR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRV161_YEAST
AccessioniPrimary (citable) accession number: P25343
Secondary accession number(s): D6VR18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: September 7, 2016
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Mutations in this gene results in sensitivity to carbon, nitrogen and sulfur starvation.
Present with 7390 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.