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P25338 (YGB0_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uncharacterized endoplasmic reticulum membrane protein YGL010W
Gene names
Ordered Locus Names:YGL010W
ORF Names:YGL021
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length174 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Not an essential protein for cell growth.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein Ref.5.

Miscellaneous

Present with 486 molecules/cell in log phase SD medium. Ref.6

Sequence similarities

To S.pombe SpAC16E8.02.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 174174Uncharacterized endoplasmic reticulum membrane protein YGL010W
PRO_0000202776

Regions

Topological domain1 – 2323Cytoplasmic Potential
Transmembrane24 – 4421Helical; Potential
Topological domain45 – 6319Lumenal Potential
Transmembrane64 – 8421Helical; Potential
Topological domain85 – 9814Cytoplasmic Potential
Transmembrane99 – 11921Helical; Potential
Topological domain120 – 13112Lumenal Potential
Transmembrane132 – 15221Helical; Potential
Topological domain153 – 17422Cytoplasmic Potential

Experimental info

Sequence conflict1051T → I Ref.1
Sequence conflict1051T → I Ref.2
Sequence conflict122 – 17453RPALI…RMQRQ → TSQR Ref.1
Sequence conflict122 – 17453RPALI…RMQRQ → TSQR Ref.2

Sequences

Sequence LengthMass (Da)Tools
P25338 [UniParc].

Last modified October 1, 1996. Version 2.
Checksum: C6C5DF3C6EDBD3B1

FASTA17420,173
        10         20         30         40         50         60 
MGEGLLDLRS QLGFYKFYHH NPKNVLIHSI FVPTILFSGS CMLHRVKIYQ SISLTAVLSV 

        70         80         90        100        110        120 
LFSIFYCLLY LPTGLLAGVL LLLLNLALID HRVDLTFKQE LGLFTIGWIF QFVGHGVFEK 

       130        140        150        160        170 
RRPALIDNLV QSLVLAPYFI MFEFLFKLGF MPRLKATLEH DLEIKQRNLR MQRQ 

« Hide

References

« Hide 'large scale' references
[1]"The YGL021 gene encodes a putative membrane protein with a putative leucine zipper motif."
Chen W., Capieaux E., Balzi E., Goffeau A.
Yeast 7:301-303(1991) [PubMed: 1882554] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 46191 / IL125-2B.
[2]"The DNA sequencing of the 17 kb HindIII fragment spanning the LEU1 and ATE1 loci on chromosome VII from Saccharomyces cerevisiae reveals the PDR6 gene, a new member of the genetic network controlling pleiotropic drug resistance."
Chen W., Balzi E., Capieaux E., Choder M., Goffeau A.
Yeast 7:287-299(1991) [PubMed: 1882553] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 46191 / IL125-2B.
[3]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed: 9169869] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[4]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S58126 Genomic DNA. Translation: AAD13893.1.
S57893 Genomic DNA. Translation: AAB19614.1.
Z72532 Genomic DNA. Translation: CAA96710.1.
BK006941 Genomic DNA. Translation: DAA08088.1.
PIRS64012.
RefSeqNP_011505.1. NM_001180875.1.

3D structure databases

ProteinModelPortalP25338.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-4727N.
IntActP25338. 1 interaction.
MINTMINT-479772.
STRINGP25338.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGL010W; YGL010W; YGL010W.
GeneID852874.
KEGGsce:YGL010W.
NMPDRfig|4932.3.peg.2613.

Organism-specific databases

CYGDYGL010w.
SGDS000002978. YGL010W.

Phylogenomic databases

eggNOGfuNOG11099.
GeneTreeEFGT00050000004862.
HOGENOMHBG688529.
OMAGLWAAQT.
OrthoDBEOG4BCHXF.

Gene expression databases

ArrayExpressP25338.
GenevestigatorP25338.
GermOnlineYGL010W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR009305. DUF962.
[Graphical view]
PfamPF06127. DUF962. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio972508.

Entry information

Entry nameYGB0_YEAST
AccessionPrimary (citable) accession number: P25338
Secondary accession number(s): D6VUC7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: October 1, 1996
Last modified: December 14, 2011
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names