Reviewed,
UniProtKB/Swiss-Prot P25338 (YGB0_YEAST)
Last modified
November 24, 2009.
Version 69.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Uncharacterized endoplasmic reticulum membrane protein YGL010W | ||||
| Gene names |
| ||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4932 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 174 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Not an essential protein for cell growth. |
| Subcellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Miscellaneous | Present with 486 molecules/cell in log phase SD medium. Ref.5 |
| Sequence similarities | To S.pombe SpAC16E8.02. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Endoplasmic reticulum Membrane |
| Domain | Transmembrane |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | endoplasmic reticulum Ref.4 Inferred from direct assay. Source: SGD integral to membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 174 | 174 | Uncharacterized endoplasmic reticulum membrane protein YGL010W | PRO_0000202776 | |||||
Regions | |||||||||
| Topological domain | 1 – 23 | 23 | Cytoplasmic Potential | ||||||
| Transmembrane | 24 – 44 | 21 | Potential | ||||||
| Topological domain | 45 – 63 | 19 | Lumenal Potential | ||||||
| Transmembrane | 64 – 84 | 21 | Potential | ||||||
| Topological domain | 85 – 98 | 14 | Cytoplasmic Potential | ||||||
| Transmembrane | 99 – 119 | 21 | Potential | ||||||
| Topological domain | 120 – 131 | 12 | Lumenal Potential | ||||||
| Transmembrane | 132 – 152 | 21 | Potential | ||||||
| Topological domain | 153 – 174 | 22 | Cytoplasmic Potential | ||||||
Experimental info | |||||||||
| Sequence conflict | 105 | 1 | T → I Ref.1 | ||||||
| Sequence conflict | 105 | 1 | T → I Ref.2 | ||||||
| Sequence conflict | 122 – 174 | 53 | RPALI…RMQRQ → TSQR Ref.1 | ||||||
| Sequence conflict | 122 – 174 | 53 | RPALI…RMQRQ → TSQR Ref.2 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The YGL021 gene encodes a putative membrane protein with a putative leucine zipper motif." Chen W., Capieaux E., Balzi E., Goffeau A. Yeast 7:301-303(1991) [PubMed: 1882554] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 46191 / IL125-2B. |
| [2] | "The DNA sequencing of the 17 kb HindIII fragment spanning the LEU1 and ATE1 loci on chromosome VII from Saccharomyces cerevisiae reveals the PDR6 gene, a new member of the genetic network controlling pleiotropic drug resistance." Chen W., Balzi E., Capieaux E., Choder M., Goffeau A. Yeast 7:287-299(1991) [PubMed: 1882553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 46191 / IL125-2B. |
| [3] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. Kleine K.Nature 387:81-84(1997) [PubMed: 9169869] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [4] | "Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. |
| [5] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [6] | "A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| S58126 Genomic DNA. Translation: AAD13893.1. S57893 Genomic DNA. Translation: AAB19614.1. Z72532 Genomic DNA. Translation: CAA96710.1. | |
| PIR | S64012. |
| RefSeq | NP_011505.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:4727N. |
| IntAct | P25338. 3 interactions. |
| STRING | P25338. |
Genome annotation databases | |
| Ensembl | YGL010W; YGL010W; YGL010W; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 852874. |
| KEGG | sce:YGL010W. |
| NMPDR | fig|4932.3.peg.2613. |
Organism-specific databases | |
| CYGD | YGL010w. |
| SGD | S000002978. YGL010W. |
Phylogenomic databases | |
| HOGENOM | P25338. |
| OMA | QAFLMAP |
| OrthoDB | EOG9HMKSS |
Gene expression databases | |
| ArrayExpress | P25338. |
| Genevestigator | P25338. |
| GermOnline | YGL010W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR009305. DUF962. [Graphical view] |
| Pfam | PF06127. DUF962. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 972508. |
Entry information
| Entry name | YGB0_YEAST | ||||||||
| Accession | Primary (citable) accession number: P25338 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome VII Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names |

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