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Protein

Probable glutathione S-transferase parA

Gene

PARA

Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei14GlutathioneBy similarity1
Binding sitei41GlutathioneBy similarity1
Binding sitei55Glutathione; via amide nitrogen and carbonyl oxygenBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Auxin signaling pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutathione S-transferase parA (EC:2.5.1.18)
Alternative name(s):
Auxin-regulated protein parA
STR246C protein
Gene namesi
Name:PARA
Synonyms:PAR
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001858631 – 220Probable glutathione S-transferase parAAdd BLAST220

Expressioni

Inductioni

By auxin.

Structurei

3D structure databases

ProteinModelPortaliP25317.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 83GST N-terminalAdd BLAST80
Domaini89 – 209GST C-terminalAdd BLAST121

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni67 – 68Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. HSP26 family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P25317-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESNNVVLLD FWPSSFGMRL RIALALKGIK YEAKEENLSD KSPLLLEMNP
60 70 80 90 100
VHKKIPILIH NSKAICESLN ILEYIDEVWH DKCPLLPSDP YERSQARFWA
110 120 130 140 150
DYIDKKIYST GRRVWSGKGE DQEEAKKEFI EILKTLEGEL GNKTYFGGDN
160 170 180 190 200
LGFVDVALVP FTSWFYSYET CANFSIEAEC PKLVVWAKTC MESESVSKSL
210 220
PHPHKIYGFV LELKHKLGLA
Length:220
Mass (Da):25,225
Last modified:May 1, 1992 - v1
Checksum:i2433BEA9D71D2AC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D90215 Genomic DNA. Translation: BAA14243.1.
M29274 mRNA. Translation: AAA67894.1.
X80829 Genomic DNA. Translation: CAA56790.1.
X80828 mRNA. Translation: CAA56789.1.
PIRiA36225.
RefSeqiNP_001312067.1. NM_001325138.1.
UniGeneiNta.3501.
Nta.4205.

Genome annotation databases

GeneIDi107772524.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D90215 Genomic DNA. Translation: BAA14243.1.
M29274 mRNA. Translation: AAA67894.1.
X80829 Genomic DNA. Translation: CAA56790.1.
X80828 mRNA. Translation: CAA56789.1.
PIRiA36225.
RefSeqiNP_001312067.1. NM_001325138.1.
UniGeneiNta.3501.
Nta.4205.

3D structure databases

ProteinModelPortaliP25317.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi107772524.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGSTXA_TOBAC
AccessioniPrimary (citable) accession number: P25317
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: October 5, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.