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P25259

- T2C2_HERAU

UniProt

P25259 - T2C2_HERAU

Protein

Type-2 restriction enzyme HgiCII

Gene

hgiCIIR

Organism
Herpetosiphon aurantiacus (Herpetosiphon giganteus)
Status
Reviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 56 (03 Sep 2014)
      Sequence version 1 (01 May 1992)
      Previous versions | rss
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    Functioni

    Recognizes the double-stranded sequence GGWCC and cleaves after G-1.

    Catalytic activityi

    Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. Type II site-specific deoxyribonuclease activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA restriction-modification system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    Restriction system

    Protein family/group databases

    REBASEi1100. HgiCII.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Type-2 restriction enzyme HgiCII (EC:3.1.21.4)
    Short name:
    R.HgiCII
    Alternative name(s):
    Endonuclease HgiCII
    Type II restriction enzyme HgiCII
    Gene namesi
    Name:hgiCIIR
    OrganismiHerpetosiphon aurantiacus (Herpetosiphon giganteus)
    Taxonomic identifieri65 [NCBI]
    Taxonomic lineageiBacteriaChloroflexiChloroflexiaHerpetosiphonalesHerpetosiphonaceaeHerpetosiphon

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 273273Type-2 restriction enzyme HgiCIIPRO_0000077312Add
    BLAST

    Family & Domainsi

    Family and domain databases

    InterProiIPR019045. Restrct_endonuc_II_TdeIII.
    [Graphical view]
    PfamiPF09520. RE_TdeIII. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P25259-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSINPITRNK IKDYLNGFID QQLAVYSQRN LREFHDVDSY LAAISSDGDL    50
    KPFHASIIPS AIMRLNRFER SLSTGLGSTF EECARVIALD HHAVAIRSYD 100
    IHTSLDQAVW ASIDLLISNI DRNNQRQIPS ITEMLEKLQS IALTGIAENH 150
    VVRADLYVQR HDGSELFFEI KSPKPNKGQC LEVMQRLLRI YAIKQNSTLP 200
    THAFYAMAYN PWGANRASYT YSIVKKYTDF TNAVVIGQEF WSLIGESSTY 250
    TELLEIYREV GLSKSSEITK KLL 273
    Length:273
    Mass (Da):31,056
    Last modified:May 1, 1992 - v1
    Checksum:i0403DF0B9F564619
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X55139 Genomic DNA. Translation: CAA38936.1.
    PIRiJC1166.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X55139 Genomic DNA. Translation: CAA38936.1 .
    PIRi JC1166.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    REBASEi 1100. HgiCII.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR019045. Restrct_endonuc_II_TdeIII.
    [Graphical view ]
    Pfami PF09520. RE_TdeIII. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Stepwise cloning and genetic organization of the seemingly unclonable HgiCII restriction-modification system from Herpetosiphon giganteus strain Hpg9, using PCR technique."
      Erdmann D., Horst G., Duesterhoeft A., Kroeger M.
      Gene 117:15-22(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: HPG9.
    2. "Organization and gene expression within restriction-modification systems of Herpetosiphon giganteus."
      Kroeger M., Blum E., Deppe E., Duesterhoeft A., Erdmann D., Kilz S., Meyer-Rogge S., Moestl D.
      Gene 157:43-47(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISCUSSION OF SEQUENCE.

    Entry informationi

    Entry nameiT2C2_HERAU
    AccessioniPrimary (citable) accession number: P25259
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: May 1, 1992
    Last modified: September 3, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Restriction enzymes and methylases
      Classification of restriction enzymes and methylases and list of entries

    External Data

    Dasty 3