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P25251

- CYSP4_BRANA

UniProt

P25251 - CYSP4_BRANA

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Protein
Cysteine proteinase COT44
Gene
N/A
Organism
Brassica napus (Rape)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

May function in an early event in cortical cell differentiation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei124 – 1241 By similarity
Active sitei260 – 2601 By similarity
Active sitei280 – 2801 By similarity

GO - Molecular functioni

  1. cysteine-type peptidase activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Hydrolase, Protease, Thiol protease

    Keywords - Biological processi

    Germination

    Protein family/group databases

    MEROPSiC01.021.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cysteine proteinase COT44 (EC:3.4.22.-)
    OrganismiBrassica napus (Rape)
    Taxonomic identifieri3708 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Propeptidei‹1 – 99›99Activation peptide Reviewed prediction
    PRO_0000026402Add
    BLAST
    Chaini100 – 328229Cysteine proteinase COT44
    PRO_0000026403Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi48 – 481N-linked (GlcNAc...) Reviewed prediction
    Glycosylationi60 – 601N-linked (GlcNAc...) Reviewed prediction
    Disulfide bondi121 ↔ 163 By similarity
    Disulfide bondi155 ↔ 196 By similarity
    Disulfide bondi254 ↔ 305 By similarity

    Keywords - PTMi

    Disulfide bond, Glycoprotein, Zymogen

    Expressioni

    Tissue specificityi

    Present in both cotyledons and axes.

    Developmental stagei

    Expressed maximally during postgerminative growth.

    Structurei

    3D structure databases

    ProteinModelPortaliP25251.
    SMRiP25251. Positions 100-320.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase C1 family.

    Family and domain databases

    InterProiIPR025661. Pept_asp_AS.
    IPR000169. Pept_cys_AS.
    IPR025660. Pept_his_AS.
    IPR013128. Peptidase_C1A.
    IPR000668. Peptidase_C1A_C.
    IPR013201. Prot_inhib_I29.
    [Graphical view]
    PANTHERiPTHR12411. PTHR12411. 1 hit.
    PfamiPF08246. Inhibitor_I29. 1 hit.
    PF00112. Peptidase_C1. 1 hit.
    [Graphical view]
    PRINTSiPR00705. PAPAIN.
    SMARTiSM00848. Inhibitor_I29. 1 hit.
    SM00645. Pept_C1. 1 hit.
    [Graphical view]
    PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
    PS00139. THIOL_PROTEASE_CYS. 1 hit.
    PS00639. THIOL_PROTEASE_HIS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P25251-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSIYLRWSLE HGKSNSNSNG IINQQDERFN IFKDNLRFID LHNENNKNAT    50
    YKLGLTIFAN LTNDEYRSLY LGARTEPVRR ITKAKNVNMK YSAAVNVDEV 100
    PVTVDWRQKG AVNAIKDQGT CGSCWAFSTA AAVEGINKIV TGELVSLSEQ 150
    ELVDCDKSYN QGCNGGLMDY AFQFIMKNGG LNTEKDYPYH GTNGKCNSLL 200
    KNSRVVTIDG YEDVPSKDET ALKRAVSYQP VSVAIDAGGR AFQHYQSGIF 250
    TGKCGTNMDH AVVAVGYGSE NGVDYWIVRN SWGTRWGEDG YIRMERNVAS 300
    KSGKCGIAIE ASYPVKYSPN PVRGTSSV 328
    Length:328
    Mass (Da):36,277
    Last modified:May 1, 1992 - v1
    Checksum:i9C95B3C488E8D0D6
    GO

    Non-terminal residue

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    PIRiJQ1121.

    Cross-referencesi

    Sequence databases

    PIRi JQ1121.

    3D structure databases

    ProteinModelPortali P25251.
    SMRi P25251. Positions 100-320.
    ModBasei Search...

    Protein family/group databases

    MEROPSi C01.021.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR025661. Pept_asp_AS.
    IPR000169. Pept_cys_AS.
    IPR025660. Pept_his_AS.
    IPR013128. Peptidase_C1A.
    IPR000668. Peptidase_C1A_C.
    IPR013201. Prot_inhib_I29.
    [Graphical view ]
    PANTHERi PTHR12411. PTHR12411. 1 hit.
    Pfami PF08246. Inhibitor_I29. 1 hit.
    PF00112. Peptidase_C1. 1 hit.
    [Graphical view ]
    PRINTSi PR00705. PAPAIN.
    SMARTi SM00848. Inhibitor_I29. 1 hit.
    SM00645. Pept_C1. 1 hit.
    [Graphical view ]
    PROSITEi PS00640. THIOL_PROTEASE_ASN. 1 hit.
    PS00139. THIOL_PROTEASE_CYS. 1 hit.
    PS00639. THIOL_PROTEASE_HIS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Spatial patterns of gene expression in Brassica napus seedlings: identification of a cortex-specific gene and localization of mRNAs encoding isocitrate lyase and a polypeptide homologous to proteinases."
      Dietrich R.A., Maslyar D.J., Heupel R.C., Harada J.J.
      Plant Cell 1:73-80(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Seed.

    Entry informationi

    Entry nameiCYSP4_BRANA
    AccessioniPrimary (citable) accession number: P25251
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1992
    Last sequence update: May 1, 1992
    Last modified: May 14, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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