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Protein

Triplex capsid protein 2

Gene

TRX2

Organism
Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.UniRule annotation1 Publication

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Triplex capsid protein 2UniRule annotation
Gene namesi
Name:TRX2UniRule annotation
ORF Names:BDLF1
OrganismiEpstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Taxonomic identifieri10377 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaeLymphocryptovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000153037 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001157321 – 301Triplex capsid protein 2Add BLAST301

Interactioni

Subunit structurei

Interacts with TRX1 and major capisd protein/MCP.UniRule annotation

Protein-protein interaction databases

IntActiP25214. 1 interactor.
MINTiMINT-6768670.

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae TRX2 protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG090000IF.

Family and domain databases

HAMAPiMF_04019. HSV_TRX2. 1 hit.
InterProiView protein in InterPro
IPR002690. Herpes_capsid_2.
PfamiView protein in Pfam
PF01802. Herpes_V23. 1 hit.

Sequencei

Sequence statusi: Complete.

P25214-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLKVVVSLS SRLYTDEIAK MQQRIGCILP LASTHGTQNV QGLGLGQVYS
60 70 80 90 100
LETVPDYVSM YNYLSDCTLA VLDEVSVDSL ILTKIVPGQT YAIKNKYQPF
110 120 130 140 150
FQWHGTGSLS VMPPVFGREH ATVKLESNDV DIVFPMVLPT PIAEEVLQKI
160 170 180 190 200
LLFNVYSRVV MQAPGNADML DVHMHLGSVS YLGHHYELAL PEVPGPLGLA
210 220 230 240 250
LLDNLSLYFC IMVTLLPRAS MRLVRGLIRH EHHDLLNLFQ EMVPDEIARI
260 270 280 290 300
DLDDLSVADD LSRMRVMMTY LQSLASLFNL GPRLATAAYS QETLTATCWL

R
Length:301
Mass (Da):33,624
Last modified:May 1, 1992 - v1
Checksum:i982B65730BF5D25C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01555 Genomic DNA. Translation: CAA24837.1.
AJ507799 Genomic DNA. Translation: CAD53446.1.
PIRiS33042.
RefSeqiYP_401696.1. NC_007605.1.

Genome annotation databases

GeneIDi3783692.
KEGGivg:3783692.

Similar proteinsi

Entry informationi

Entry nameiTRX2_EBVB9
AccessioniPrimary (citable) accession number: P25214
Secondary accession number(s): Q777C3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: March 15, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families