P25143 (ADHR_DROAM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Alcohol dehydrogenase-related 31 kDa protein

Gene names

Name:

Adhr

Organism

Drosophila ambigua (Fruit fly)

Taxonomic identifier

7216 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	281 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Gene Ontology (GO)
Molecular function	alcohol dehydrogenase (NAD) activity Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 281	281	Alcohol dehydrogenase-related 31 kDa protein		PRO_0000054502
Regions
	Nucleotide binding	11 – 34	24	NAD or NADP By similarity
Sites
	Active site	152	1	Proton acceptor By similarity
	Binding site	139	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	P25143 [UniParc]. Last modified May 1, 1992. Version 1. Checksum: 7E53C62EA82B68CE	FASTA	281	31,227
	10 20 30 40 50 60 MYDLAGKHVC YVADCGGIAL ETSKVLMTKN IAKLAILQSV ENQPAIAQLQ SIKHSTQIFF 70 80 90 100 110 120 WTFDVTMARE EMKKYFDEVM VQMDYIDVLI NGATLCDERN IDATINTNLT GMMNTVATVL 130 140 150 160 170 180 PYMDRKMGGS GGLIVNVTSV IGLDPSPVFC AYSASKFGVI GFTRSLADPL YYNQNGVAVM 190 200 210 220 230 240 AVCCGPTKVF VDRELNAFLE YGQTFADRLR LAPCQSTAVC GQNIVNAIER SQNGQIWIAD 250 260 270 280 KGGLELVTLH WYWHMADQFI SYMQSTDDED QECFLSAAYR K

References

[1]	"The Adh genomic region of Drosophila ambigua: evolutionary trends in different species." Marfany G., Gonzalez-Duarte R. J. Mol. Evol. 32:454-462(1991) [PubMed: 1908016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X54813 Genomic DNA. Translation: CAA38582.1.
PIR	S16454.
3D structure databases
ProteinModelPortal	P25143.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0012100. Damb\Adhr.
Family and domain databases
InterPro	IPR002427. ADH-rel. IPR002424. ADH_insect. IPR002198. DH_sc/Rdtase_SDR. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR01170. ADHRELATED. PR01167. INSADHFAMILY. PR00080. SDRFAMILY.
PROSITE	PS00061. ADH_SHORT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADHR_DROAM

Accession

Primary (citable) accession number: P25143

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1992
Last sequence update:	May 1, 1992
Last modified:	December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project