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Protein

ADP,ATP carrier protein, mitochondrial

Gene

ANT

Organism
Solanum tuberosum (Potato)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.

Miscellaneous

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. At least 2 of the odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei159NucleotideBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein, mitochondrial
Alternative name(s):
ADP/ATP translocase
Adenine nucleotide translocator
Short name:
ANT
Gene namesi
Name:ANT
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
Proteomesi
  • UP000011115 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei83 – 117Helical; Name=1By similarityAdd BLAST35
Transmembranei154 – 178Helical; Name=2By similarityAdd BLAST25
Transmembranei187 – 221Helical; Name=3By similarityAdd BLAST35
Transmembranei256 – 283Helical; Name=4By similarityAdd BLAST28
Transmembranei288 – 322Helical; Name=5By similarityAdd BLAST35
Transmembranei351 – 376Helical; Name=6By similarityAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 77MitochondrionSequence analysisAdd BLAST77
ChainiPRO_000001925178 – 386ADP,ATP carrier protein, mitochondrialAdd BLAST309

Proteomic databases

PRIDEiP25083.

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi4113.PGSC0003DMT400035380.

Structurei

3D structure databases

ProteinModelPortaliP25083.
SMRiP25083.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati84 – 177Solcar 1Add BLAST94
Repeati189 – 281Solcar 2Add BLAST93
Repeati289 – 375Solcar 3Add BLAST87

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi316 – 321Substrate recognitionBy similarity6

Sequence similaritiesi

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
InParanoidiP25083.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P25083-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADMNQHPTV FQKAANQLDL RSSLSQDVHA RYGGVQPAIY QRHFAYGNYS
60 70 80 90 100
NAGLQRGQAT QDLSLITSNA SPVFVQAPQE KGFAAFATDF LMGGVSAAVS
110 120 130 140 150
KTAAAPIERV KLLIQNQDEM LKAGRLSEPY KGIGECFGRT IKEEGFGSLW
160 170 180 190 200
RGNTANVIRY FPTQALNFAF KDYFKRLFNF KKDRDGYWKW FAGNLASGGA
210 220 230 240 250
AGASSLFFVY SLDYARTRLA NDRKASKKGG ERQFNGLVDV YKKTLKSDGI
260 270 280 290 300
AGLYRGFNIS CVGIIVYRGL YFGMYDSLKP VLLTGNLQDS FFASFGLGWL
310 320 330 340 350
ITNGAGLASY PIDTVRRRMM MTSGEAVKYK SSLDAFSQIV KNEGPKSLFK
360 370 380
GAGANILRAV AGAGVLAGYD KLQVLVLGKK FGSGGA
Length:386
Mass (Da):42,058
Last modified:May 1, 1992 - v1
Checksum:i68223D27A0B4EFB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X62123 mRNA. Translation: CAA44054.1.
PIRiS17917.
S21974.
UniGeneiStu.18045.

Similar proteinsi

Entry informationi

Entry nameiADT1_SOLTU
AccessioniPrimary (citable) accession number: P25083
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: March 15, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families