##gff-version 3
P25045	UniProtKB	Chain	1	558	.	.	.	ID=PRO_0000163856;Note=Serine palmitoyltransferase 1	
P25045	UniProtKB	Topological domain	1	49	.	.	.	Note=Lumenal;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Transmembrane	50	84	.	.	.	Note=Helical	
P25045	UniProtKB	Topological domain	85	341	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Transmembrane	342	371	.	.	.	Note=Helical	
P25045	UniProtKB	Topological domain	372	424	.	.	.	Note=Lumenal;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Transmembrane	425	457	.	.	.	Note=Helical	
P25045	UniProtKB	Topological domain	458	558	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Modified residue	121	121	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:17330950;Dbxref=PMID:17330950	
P25045	UniProtKB	Mutagenesis	24	26	.	.	.	Note=No effect on stability. No effect on LCB2 stabilization. YLW->DRS;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	50	85	.	.	.	Note=No effect on stability. No effect on LCB2 stabilization. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	66	68	.	.	.	Note=No effect on stability. No effect on LCB2 stabilization. YGI->DVK;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	180	180	.	.	.	Note=Loss of activity. No effect on interaction with LCB2. C->W%2CY;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11781309;Dbxref=PMID:11781309	
P25045	UniProtKB	Mutagenesis	191	191	.	.	.	Note=Loss of activity. No effect on interaction with LCB2. V->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11781309;Dbxref=PMID:11781309	
P25045	UniProtKB	Mutagenesis	342	371	.	.	.	Note=Unstable. Destabilizes LCB2. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	371	386	.	.	.	Note=No effect on stability. Destabilizes LCB2. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	386	416	.	.	.	Note=Unstable. Destabilizes LCB2. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	416	425	.	.	.	Note=No effect on stability. Destabilizes LCB2. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	433	458	.	.	.	Note=Unstable. Destabilizes LCB2. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	549	550	.	.	.	Note=No effect on stability. Partially stabilizes LCB2. IL->AS;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Mutagenesis	549	550	.	.	.	Note=No effect on stability. Partially stabilizes LCB2. IL->PR;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15485854;Dbxref=PMID:15485854	
P25045	UniProtKB	Sequence conflict	443	443	.	.	.	Note=A->P;Ontology_term=ECO:0000305;evidence=ECO:0000305