Reviewed,
UniProtKB/Swiss-Prot P25017 (TR2M2_AGRVI)
Last modified
June 16, 2009.
Version 53.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Tryptophan 2-monooxygenase EC=1.13.12.3 | ||
| Gene names |
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| Encoded on | Plasmid pTiTM4 | ||
| Organism | Agrobacterium vitis (Rhizobium vitis) | ||
| Taxonomic identifier | 373 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium |
Protein attributes
| Sequence length | 755 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | L-tryptophan + O2 = (indol-3-yl)acetamide + CO2 + H2O. |
| Pathway | |
| Sequence similarities | Belongs to the tryptophan 2-monooxygenase family. |
| Caution | The plasmid pTiTM4 carries two T-regions, the TA and TB region, both of which have a functional iaaM gene, with low homology between them. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Auxin biosynthesis |
| Disease | Crown gall tumor |
| Molecular function | Monooxygenase Oxidoreductase |
| Technical term | Plasmid |
| Gene Ontology (GO) | |
| Biological process | auxin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | electron carrier activity Inferred from electronic annotation. Source: InterPro tryptophan 2-monooxygenase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 755 | 755 | Tryptophan 2-monooxygenase | PRO_0000065591 | |||
Sequences
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References
| [1] | "Sequence of Agrobacterium tumefaciens biotype III auxin genes." Bonnard G., Vincent F., Otten L. Plant Mol. Biol. 16:733-738(1991) [PubMed: 1868204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: TM4. |
| [2] | Otten L., de Ruffray P. Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: CG474. |
Cross-references
Sequence databases | |
|---|---|
| X56185 Genomic DNA. Translation: CAA39646.1. U83987 Genomic DNA. Translation: AAB41874.1. | |
3D structure databases | |
| ModBase | Search... |
Enzyme and pathway databases | |
| BRENDA | 1.13.12.3. 97084. |
Family and domain databases | |
| InterPro | IPR000759. Adrndx_reductase. IPR002937. Amino_oxidase. IPR006064. Glycosidase. IPR012142. Trp_2-mOase. [Graphical view] |
| Pfam | PF01593. Amino_oxidase. 1 hit. PF02027. RolB_RolC. 1 hit. [Graphical view] |
| PIRSF | PIRSF000319. Trp_2-mono_O2ase. 1 hit. |
| PRINTS | PR00419. ADXRDTASE. |
| ProtoNet | Search... |
Entry information
| Entry name | TR2M2_AGRVI | ||||||||
| Accession | Primary (citable) accession number: P25017 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


