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Protein

Cyclin puc1

Gene

puc1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Function in exit from the mitotic cycle. Contributes to negative regulation of the timing of sexual development in fission yeast, and functions at the transition between cycling and non-cycling cells. Interacts with protein kinase A.

GO - Molecular functioni

  • cyclin-dependent protein serine/threonine kinase regulator activity Source: PomBase

GO - Biological processi

  • cell division Source: UniProtKB-KW
  • regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle Source: PomBase
  • regulation of exit from mitosis Source: PomBase
  • regulation of G1/S transition of mitotic cell cycle Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Cyclin

Keywords - Biological processi

Cell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin puc1
Gene namesi
Name:puc1
ORF Names:SPBC19F5.01c, SPBP8B7.32c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC19F5.01c.
PomBaseiSPBC19F5.01c. puc1.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 359359Cyclin puc1PRO_0000080418Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi277179. 18 interactions.
DIPiDIP-659N.
MINTiMINT-4687868.

Structurei

3D structure databases

ProteinModelPortaliP25009.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family.Curated

Phylogenomic databases

eggNOGiCOG5024.
InParanoidiP25009.
OrthoDBiEOG7FNCJX.
PhylomeDBiP25009.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR013763. Cyclin-like.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.

Sequencei

Sequence statusi: Complete.

P25009-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVSSNEEQL TAHTPTSSSS IEPKILAACS YSLSVGPCSL AVSPKGVNSK
60 70 80 90 100
SPSLKNETAF VVDSVSTLSA ESSALLYNTQ SSLLTGLSMN GYLGEYQEDI
110 120 130 140 150
IHHLITREKN FLLNVHLSNQ QPELRWSMRP ALVNFIVEIH NGFDLSIDTL
160 170 180 190 200
PLSISLMDSY VSRRVVYCKH IQLVACVCLW IASKFHETED RVPLLQELKL
210 220 230 240 250
ACKNIYAEDL FIRMERHILD TLDWDISIPT PASYIPVLDP IFFLVLDASM
260 270 280 290 300
FVPNLFKFPA SKIACSVMNI VNEHVGSFLL THPSMESYRK DDNFLWPEDL
310 320 330 340 350
DTVTSYMENM SKRYANEECT DLLFSSLGRI SSILAKKYPE QCAMAAWCNM

TEKDTERTL
Length:359
Mass (Da):40,430
Last modified:March 1, 1992 - v1
Checksum:i72DB0BB149041B4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59154 Genomic DNA. Translation: CAA41868.1.
X74451 Genomic DNA. Translation: CAA52460.1.
CU329671 Genomic DNA. Translation: CAA21817.1.
PIRiS15406.
S36408.
RefSeqiNP_596539.1. NM_001022460.2.

Genome annotation databases

EnsemblFungiiSPBC19F5.01c.1; SPBC19F5.01c.1:pep; SPBC19F5.01c.
GeneIDi2540654.
KEGGispo:SPBC19F5.01c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59154 Genomic DNA. Translation: CAA41868.1.
X74451 Genomic DNA. Translation: CAA52460.1.
CU329671 Genomic DNA. Translation: CAA21817.1.
PIRiS15406.
S36408.
RefSeqiNP_596539.1. NM_001022460.2.

3D structure databases

ProteinModelPortaliP25009.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277179. 18 interactions.
DIPiDIP-659N.
MINTiMINT-4687868.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC19F5.01c.1; SPBC19F5.01c.1:pep; SPBC19F5.01c.
GeneIDi2540654.
KEGGispo:SPBC19F5.01c.

Organism-specific databases

EuPathDBiFungiDB:SPBC19F5.01c.
PomBaseiSPBC19F5.01c. puc1.

Phylogenomic databases

eggNOGiCOG5024.
InParanoidiP25009.
OrthoDBiEOG7FNCJX.
PhylomeDBiP25009.

Miscellaneous databases

NextBioi20801778.
PROiP25009.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR013763. Cyclin-like.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of a G1-type cyclin puc1+ in the fission yeast Schizosaccharomyces pombe."
    Forsburg S.L., Nurse P.
    Nature 351:245-247(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Erratum
    Forsburg S.L., Nurse P.
    Nature 352:648-648(1991)
  3. "Analysis of the Schizosaccharomyces pombe cyclin puc1: evidence for a role in cell cycle exit."
    Forsburg S.L., Nurse P.
    J. Cell Sci. 107:601-613(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  4. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiPUC1_SCHPO
AccessioniPrimary (citable) accession number: P25009
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: July 22, 2015
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.