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P25009

- PUC1_SCHPO

UniProt

P25009 - PUC1_SCHPO

Protein

Cyclin puc1

Gene

puc1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 1 (01 Mar 1992)
      Previous versions | rss
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    Functioni

    Function in exit from the mitotic cycle. Contributes to negative regulation of the timing of sexual development in fission yeast, and functions at the transition between cycling and non-cycling cells. Interacts with protein kinase A.

    GO - Molecular functioni

    1. cyclin-dependent protein serine/threonine kinase regulator activity Source: PomBase

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. regulation of cyclin-dependent protein serine/threonine kinase activity Source: PomBase
    4. regulation of exit from mitosis Source: PomBase

    Keywords - Molecular functioni

    Cyclin

    Keywords - Biological processi

    Cell cycle, Cell division

    Enzyme and pathway databases

    ReactomeiREACT_220849. Recognition and association of DNA glycosylase with site containing an affected pyrimidine.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cyclin puc1
    Gene namesi
    Name:puc1
    ORF Names:SPBC19F5.01c, SPBP8B7.32c
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome II

    Organism-specific databases

    PomBaseiSPBC19F5.01c.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: PomBase
    2. nucleus Source: PomBase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 359359Cyclin puc1PRO_0000080418Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    BioGridi277179. 18 interactions.
    DIPiDIP-659N.
    MINTiMINT-4687868.
    STRINGi4896.SPBC19F5.01c-1.

    Structurei

    3D structure databases

    ProteinModelPortaliP25009.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cyclin family.Curated

    Phylogenomic databases

    eggNOGiCOG5024.
    OrthoDBiEOG7FNCJX.
    PhylomeDBiP25009.

    Family and domain databases

    Gene3Di1.10.472.10. 1 hit.
    InterProiIPR013763. Cyclin-like.
    IPR014399. Cyclin_CLN/Puc1.
    IPR006671. Cyclin_N.
    [Graphical view]
    PfamiPF00134. Cyclin_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001770. Cyclin_CLN. 1 hit.
    SMARTiSM00385. CYCLIN. 1 hit.
    [Graphical view]
    SUPFAMiSSF47954. SSF47954. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P25009-1 [UniParc]FASTAAdd to Basket

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    MLVSSNEEQL TAHTPTSSSS IEPKILAACS YSLSVGPCSL AVSPKGVNSK    50
    SPSLKNETAF VVDSVSTLSA ESSALLYNTQ SSLLTGLSMN GYLGEYQEDI 100
    IHHLITREKN FLLNVHLSNQ QPELRWSMRP ALVNFIVEIH NGFDLSIDTL 150
    PLSISLMDSY VSRRVVYCKH IQLVACVCLW IASKFHETED RVPLLQELKL 200
    ACKNIYAEDL FIRMERHILD TLDWDISIPT PASYIPVLDP IFFLVLDASM 250
    FVPNLFKFPA SKIACSVMNI VNEHVGSFLL THPSMESYRK DDNFLWPEDL 300
    DTVTSYMENM SKRYANEECT DLLFSSLGRI SSILAKKYPE QCAMAAWCNM 350
    TEKDTERTL 359
    Length:359
    Mass (Da):40,430
    Last modified:March 1, 1992 - v1
    Checksum:i72DB0BB149041B4B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59154 Genomic DNA. Translation: CAA41868.1.
    X74451 Genomic DNA. Translation: CAA52460.1.
    CU329671 Genomic DNA. Translation: CAA21817.1.
    PIRiS15406.
    S36408.
    RefSeqiNP_596539.1. NM_001022460.2.

    Genome annotation databases

    EnsemblFungiiSPBC19F5.01c.1; SPBC19F5.01c.1:pep; SPBC19F5.01c.
    GeneIDi2540654.
    KEGGispo:SPBC19F5.01c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59154 Genomic DNA. Translation: CAA41868.1 .
    X74451 Genomic DNA. Translation: CAA52460.1 .
    CU329671 Genomic DNA. Translation: CAA21817.1 .
    PIRi S15406.
    S36408.
    RefSeqi NP_596539.1. NM_001022460.2.

    3D structure databases

    ProteinModelPortali P25009.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 277179. 18 interactions.
    DIPi DIP-659N.
    MINTi MINT-4687868.
    STRINGi 4896.SPBC19F5.01c-1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPBC19F5.01c.1 ; SPBC19F5.01c.1:pep ; SPBC19F5.01c .
    GeneIDi 2540654.
    KEGGi spo:SPBC19F5.01c.

    Organism-specific databases

    PomBasei SPBC19F5.01c.

    Phylogenomic databases

    eggNOGi COG5024.
    OrthoDBi EOG7FNCJX.
    PhylomeDBi P25009.

    Enzyme and pathway databases

    Reactomei REACT_220849. Recognition and association of DNA glycosylase with site containing an affected pyrimidine.

    Miscellaneous databases

    NextBioi 20801778.

    Family and domain databases

    Gene3Di 1.10.472.10. 1 hit.
    InterProi IPR013763. Cyclin-like.
    IPR014399. Cyclin_CLN/Puc1.
    IPR006671. Cyclin_N.
    [Graphical view ]
    Pfami PF00134. Cyclin_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001770. Cyclin_CLN. 1 hit.
    SMARTi SM00385. CYCLIN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47954. SSF47954. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Identification of a G1-type cyclin puc1+ in the fission yeast Schizosaccharomyces pombe."
      Forsburg S.L., Nurse P.
      Nature 351:245-247(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Erratum
      Forsburg S.L., Nurse P.
      Nature 352:648-648(1991)
    3. "Analysis of the Schizosaccharomyces pombe cyclin puc1: evidence for a role in cell cycle exit."
      Forsburg S.L., Nurse P.
      J. Cell Sci. 107:601-613(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    4. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.

    Entry informationi

    Entry nameiPUC1_SCHPO
    AccessioniPrimary (citable) accession number: P25009
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 1992
    Last sequence update: March 1, 1992
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3