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Reviewed, UniProtKB/Swiss-Prot P24935 (E311_ADE02)

Last modified February 9, 2010. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Early E3A 11.6 kDa glycoprotein
OrganismHuman adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
Taxonomic identifier10515 [NCBI]
Taxonomic lineageViruses › dsDNA viruses, no RNA stage › Adenoviridae › Mastadenovirus
Virus hostHomo sapiens (Human) [TaxID: 9606]

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Protein attributes

Sequence length101 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

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General annotation (Comments)

Subcellular location

Host nucleus membrane; Single-pass membrane protein.

Post-translational modification

N-glycosylated and probably also O-glycosylated.

Sequence similarities

Belongs to the adenoviridae E3A-1 family.

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Ontologies

Keywords
   Cellular componentHost membrane
Host nucleus
Membrane
   Developmental stageEarly protein
   DomainTransmembrane
   PTMGlycoprotein
Gene Ontology (GO)
   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 101101Early E3A 11.6 kDa glycoprotein
PRO_0000221736

Regions

Transmembrane41 – 6222 Potential

Amino acid modifications

Glycosylation141N-linked (GlcNAc...); by host Potential

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Sequences

Sequence LengthMass (Da)Tools
P24935-1 [UniParc].

Last modified March 1, 1992. Version 1.
Checksum: FB89FCC6E921E84B

FASTA10111,644
        10         20         30         40         50         60 
MTGSTIAPTT DYRNTTATGL TSALNLPQVH AFVNDWASLD MWWFSIALMF VCLIIMWLIC 

        70         80         90        100 
CLKRRRARPP IYRPIIVLNP HNEKIHRLDG LKPCSLLLQY D

« Hide

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References

[1]"Nucleotide sequence of the EcoRI D fragment of adenovirus 2 genome."
Herisse J., Courtois G., Galibert F.
Nucleic Acids Res. 8:2173-2192(1980) [PubMed: 6253880] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The E3-11.6K protein of adenovirus is an Asn-glycosylated integral membrane protein that localizes to the nuclear membrane."
Scaria A., Tollefson A.E., Saha S.K., Wold W.S.M.
Virology 191:743-753(1992) [PubMed: 1448922] [Abstract]
Cited for: IDENTIFICATION OF PROTEIN.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		J01917 Genomic DNA. Translation: AAA92222.1.
RefSeqAP_000185.1.
NP_040532.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2652987.

Family and domain databases

InterProIPR008652. Hum_adeno_E3A.
[Graphical view]
ProDomPD015371. Hum_adeno_E3A. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

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Entry information

Entry nameE311_ADE02
AccessionPrimary (citable) accession number: P24935
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: February 9, 2010
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectVirus (Virus annotation project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents