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Protein

Rubrerythrin

Gene

rbr

Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide.By similarity

Cofactori

Fe3+Note: Binds 3 Fe3+ ions per subunit.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi20Zinc or iron 11
Metal bindingi53Iron 21
Metal bindingi53Zinc or iron 11
Metal bindingi94Iron 21
Metal bindingi97Zinc or iron 11
Metal bindingi128Iron 21
Metal bindingi128Zinc or iron 11
Metal bindingi131Iron 21
Metal bindingi158Iron 31
Metal bindingi161Iron 31
Metal bindingi174Iron 31
Metal bindingi177Iron 31

GO - Molecular functioni

  • iron ion binding Source: UniProtKB
  • oxidoreductase activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Iron, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Rubrerythrin
Short name:
Rr
Gene namesi
Name:rbr
Ordered Locus Names:DVU_3094
OrganismiDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Taxonomic identifieri882 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000002194 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001350641 – 191RubrerythrinAdd BLAST191

Proteomic databases

PaxDbiP24931.

Interactioni

Subunit structurei

Homodimer. Possesses two rubredoxin-like centers and two non-sulfur oxo-bridged di-iron centers per dimer.

Protein-protein interaction databases

STRINGi882.DVU3094.

Structurei

Secondary structure

1191
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi5 – 7Combined sources3
Helixi8 – 36Combined sources29
Helixi40 – 63Combined sources24
Helixi83 – 99Combined sources17
Helixi101 – 112Combined sources12
Helixi115 – 143Combined sources29
Beta strandi147 – 158Combined sources12
Turni159 – 161Combined sources3
Beta strandi164 – 169Combined sources6
Turni175 – 177Combined sources3
Helixi181 – 183Combined sources3
Beta strandi184 – 186Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B71X-ray1.90A1-191[»]
1DVBX-ray1.90A1-191[»]
1JYBX-ray2.20A1-191[»]
1LKMX-ray1.69A1-191[»]
1LKOX-ray1.63A1-191[»]
1LKPX-ray1.64A1-191[»]
1QYBX-ray1.75A1-191[»]
1RYTX-ray2.10A2-191[»]
1S2ZX-ray1.75A1-191[»]
1S30X-ray2.05A1-191[»]
ProteinModelPortaliP24931.
SMRiP24931.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP24931.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 146Ferritin-like diironPROSITE-ProRule annotationAdd BLAST146
Domaini153 – 191Rubredoxin-likePROSITE-ProRule annotationAdd BLAST39

Sequence similaritiesi

Contains 1 ferritin-like diiron domain.PROSITE-ProRule annotation
Contains 1 rubredoxin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108RAC. Bacteria.
COG1592. LUCA.
OMAiCKHAKKF.
OrthoDBiPOG091H01WH.
PhylomeDBiP24931.

Family and domain databases

CDDicd01041. Rubrerythrin. 1 hit.
Gene3Di1.20.1260.10. 1 hit.
2.20.28.10. 1 hit.
InterProiIPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR024934. Rubredoxin-like_dom.
IPR004039. Rubredoxin-type_fold.
IPR003251. Rubrerythrin.
[Graphical view]
PfamiPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS50905. FERRITIN_LIKE. 1 hit.
PS50903. RUBREDOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24931-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSLKGSRTE KNILTAFAGE SQARNRYNYF GGQAKKDGFV QISDIFAETA
60 70 80 90 100
DQEREHAKRL FKFLEGGDLE IVAAFPAGII ADTHANLIAS AAGEHHEYTE
110 120 130 140 150
MYPSFARIAR EEGYEEIARV FASIAVAEEF HEKRFLDFAR NIKEGRVFLR
160 170 180 190
EQATKWRCRN CGYVHEGTGA PELCPACAHP KAHFELLGIN W
Length:191
Mass (Da):21,544
Last modified:March 1, 1992 - v1
Checksum:iBCF8E9A2659F1138
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82323 Genomic DNA. Translation: AAB39991.1.
AE017285 Genomic DNA. Translation: AAS97565.1.
PIRiA41191. A39492.
RefSeqiWP_010940353.1. NC_002937.3.
YP_012305.1. NC_002937.3.

Genome annotation databases

EnsemblBacteriaiAAS97565; AAS97565; DVU_3094.
GeneIDi2795966.
KEGGidvu:DVU3094.
PATRICi32065734. VBIDesVul119526_2807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82323 Genomic DNA. Translation: AAB39991.1.
AE017285 Genomic DNA. Translation: AAS97565.1.
PIRiA41191. A39492.
RefSeqiWP_010940353.1. NC_002937.3.
YP_012305.1. NC_002937.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B71X-ray1.90A1-191[»]
1DVBX-ray1.90A1-191[»]
1JYBX-ray2.20A1-191[»]
1LKMX-ray1.69A1-191[»]
1LKOX-ray1.63A1-191[»]
1LKPX-ray1.64A1-191[»]
1QYBX-ray1.75A1-191[»]
1RYTX-ray2.10A2-191[»]
1S2ZX-ray1.75A1-191[»]
1S30X-ray2.05A1-191[»]
ProteinModelPortaliP24931.
SMRiP24931.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi882.DVU3094.

Proteomic databases

PaxDbiP24931.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS97565; AAS97565; DVU_3094.
GeneIDi2795966.
KEGGidvu:DVU3094.
PATRICi32065734. VBIDesVul119526_2807.

Phylogenomic databases

eggNOGiENOG4108RAC. Bacteria.
COG1592. LUCA.
OMAiCKHAKKF.
OrthoDBiPOG091H01WH.
PhylomeDBiP24931.

Miscellaneous databases

EvolutionaryTraceiP24931.

Family and domain databases

CDDicd01041. Rubrerythrin. 1 hit.
Gene3Di1.20.1260.10. 1 hit.
2.20.28.10. 1 hit.
InterProiIPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR024934. Rubredoxin-like_dom.
IPR004039. Rubredoxin-type_fold.
IPR003251. Rubrerythrin.
[Graphical view]
PfamiPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS50905. FERRITIN_LIKE. 1 hit.
PS50903. RUBREDOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRUBY_DESVH
AccessioniPrimary (citable) accession number: P24931
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: November 30, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Was originally thought to have inorganic pyrophosphatase activity.Curated

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.