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P24879 (COX3_ASCSU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismAscaris suum (Pig roundworm) (Ascaris lumbricoides)
Taxonomic identifier6253 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaAscarididaAscaridoideaAscarididaeAscaris

Protein attributes

Sequence length255 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 255255Cytochrome c oxidase subunit 3
PRO_0000183741

Regions

Transmembrane12 – 3221Helical; Potential
Transmembrane35 – 5521Helical; Potential
Transmembrane77 – 9721Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane153 – 17321Helical; Potential
Transmembrane190 – 21021Helical; Potential
Transmembrane231 – 25121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P24879 [UniParc].

Last modified November 1, 1995. Version 2.
Checksum: 05A992684AC92755

FASTA25529,094
        10         20         30         40         50         60 
MFHNFHILSL SSYPILIFCS SLGFTSSLVV FFKNGIFGGL LFCLFSIFLV SFAWGKDIVM 

        70         80         90        100        110        120 
EGLSGYHNFF VMDGFKFGVL VFIFSEFMFF FGIFWTFFDA ALVPAHDVGG VWSPIGMHLV 

       130        140        150        160        170        180 
NPFGVPLLNT IILLSSGVSV TWAHYSLLSN KGCANSLMLT CILAVYFTGI QLMEYKEASF 

       190        200        210        220        230        240 
SISDGIFGSI FYLSTGFHGV HVLFGGLFLF FNLLRLLMSH FNYNHHLGLE FAIIYWHFVD 

       250 
VVWLFLFVFV YWWSY 

« Hide

References

[1]"The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum."
Okimoto R., Macfarlane J.L., Clary D.O., Wolstenholme D.R.
Genetics 130:471-498(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Body wall muscle and Egg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X54253 Genomic DNA. Translation: CAA38169.1.
PIRS26020.
RefSeqNP_006947.1. NC_001327.1.

3D structure databases

ProteinModelPortalP24879.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID807665.

Organism-specific databases

CTD4514.

Phylogenomic databases

ProtClustDBMTH00083.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_ASCSU
AccessionPrimary (citable) accession number: P24879
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families