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P24826

- CHS1_SOYBN

UniProt

P24826 - CHS1_SOYBN

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Protein

Chalcone synthase 1

Gene

CHS1

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 1 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 1
Gene namesi
Name:CHS1
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
ProteomesiUP000008827: Chromosome 8

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 388388Chalcone synthase 1PRO_0000216062Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP24826.

Structurei

3D structure databases

ProteinModelPortaliP24826.
SMRiP24826. Positions 3-388.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Phylogenomic databases

InParanoidiP24826.
KOiK00660.
OMAiQVEKPLF.

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24826-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVSVEEIRKA QRAEGPATVM AIGTATPPNC VDQSTYPDYY FRITNSEHMT
60 70 80 90 100
ELKEKFKRMC DKSMIKKRYM YLNEEILKEN PSVCAYMAPS LDARQDMVVV
110 120 130 140 150
EVPKLGKEAA TKAIKEWGQP KSKITHLIFC TTSGVDMPGA DYQLTKLLGL
160 170 180 190 200
RPSVKRYMMY QQGCFAGGTV LRLAKDLAEN NKGARVLVVC SEITAVTFRG
210 220 230 240 250
PTDTHLDSLV GQALFGDGAA AVIVGSDPLP VEKPLFQLVW TAQTILPDSE
260 270 280 290 300
GAIDGHLREV GLTFHLLKDV PGLISKNIEK ALVEAFQPLG ISDYNSIFWI
310 320 330 340 350
AHPGGPAILD QVEAKLGLKP EKMEATRHVL SEYGNMSSAC VLFILDQMRK
360 370 380
KSIENGLGTT GEGLDWGVLF GFGPGLTVET VVLRSVTL
Length:388
Mass (Da):42,516
Last modified:March 1, 1992 - v1
Checksum:i73AC3B59A4E91BB1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54644 Genomic DNA. Translation: CAA38456.1.
PIRiS15006. SYSYC1.
RefSeqiXP_003531225.1. XM_003531177.2.
XP_006585155.1. XM_006585092.1.
UniGeneiGma.17605.

Genome annotation databases

EnsemblPlantsiGLYMA08G11620.1; GLYMA08G11620.1; GLYMA08G11620.
GeneIDi732575.
KEGGigmx:732575.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54644 Genomic DNA. Translation: CAA38456.1 .
PIRi S15006. SYSYC1.
RefSeqi XP_003531225.1. XM_003531177.2.
XP_006585155.1. XM_006585092.1.
UniGenei Gma.17605.

3D structure databases

ProteinModelPortali P24826.
SMRi P24826. Positions 3-388.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi GLYMA08G11620.1 ; GLYMA08G11620.1 ; GLYMA08G11620 .
GeneIDi 732575.
KEGGi gmx:732575.

Phylogenomic databases

InParanoidi P24826.
KOi K00660.
OMAi QVEKPLF.

Enzyme and pathway databases

UniPathwayi UPA00154 .

Gene expression databases

Genevestigatori P24826.

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The nucleotide sequence of gene 1 of the soybean chalcone synthase multigene family."
    Akada S., Kung S.D., Dube S.K.
    Plant Mol. Biol. 16:751-752(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Williams.

Entry informationi

Entry nameiCHS1_SOYBN
AccessioniPrimary (citable) accession number: P24826
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: October 29, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3