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P24826

- CHS1_SOYBN

UniProt

P24826 - CHS1_SOYBN

Protein

Chalcone synthase 1

Gene

CHS1

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Mar 1992)
      Previous versions | rss
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    Functioni

    The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chalcone synthase 1 (EC:2.3.1.74)
    Alternative name(s):
    Naringenin-chalcone synthase 1
    Gene namesi
    Name:CHS1
    OrganismiGlycine max (Soybean) (Glycine hispida)
    Taxonomic identifieri3847 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
    ProteomesiUP000008827: Chromosome 8

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 388388Chalcone synthase 1PRO_0000216062Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP24826.

    Structurei

    3D structure databases

    ProteinModelPortaliP24826.
    SMRiP24826. Positions 3-388.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chalcone/stilbene synthases family.Curated

    Phylogenomic databases

    KOiK00660.
    OMAiQVEKPLF.

    Family and domain databases

    Gene3Di3.40.47.10. 2 hits.
    InterProiIPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000451. PKS_III. 1 hit.
    SUPFAMiSSF53901. SSF53901. 2 hits.
    PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P24826-1 [UniParc]FASTAAdd to Basket

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    MVSVEEIRKA QRAEGPATVM AIGTATPPNC VDQSTYPDYY FRITNSEHMT    50
    ELKEKFKRMC DKSMIKKRYM YLNEEILKEN PSVCAYMAPS LDARQDMVVV 100
    EVPKLGKEAA TKAIKEWGQP KSKITHLIFC TTSGVDMPGA DYQLTKLLGL 150
    RPSVKRYMMY QQGCFAGGTV LRLAKDLAEN NKGARVLVVC SEITAVTFRG 200
    PTDTHLDSLV GQALFGDGAA AVIVGSDPLP VEKPLFQLVW TAQTILPDSE 250
    GAIDGHLREV GLTFHLLKDV PGLISKNIEK ALVEAFQPLG ISDYNSIFWI 300
    AHPGGPAILD QVEAKLGLKP EKMEATRHVL SEYGNMSSAC VLFILDQMRK 350
    KSIENGLGTT GEGLDWGVLF GFGPGLTVET VVLRSVTL 388
    Length:388
    Mass (Da):42,516
    Last modified:March 1, 1992 - v1
    Checksum:i73AC3B59A4E91BB1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54644 Genomic DNA. Translation: CAA38456.1.
    PIRiS15006. SYSYC1.
    RefSeqiXP_003531225.1. XM_003531177.2.
    XP_006585155.1. XM_006585092.1.
    UniGeneiGma.17605.

    Genome annotation databases

    EnsemblPlantsiGLYMA08G11620.1; GLYMA08G11620.1; GLYMA08G11620.
    GeneIDi732575.
    KEGGigmx:732575.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54644 Genomic DNA. Translation: CAA38456.1 .
    PIRi S15006. SYSYC1.
    RefSeqi XP_003531225.1. XM_003531177.2.
    XP_006585155.1. XM_006585092.1.
    UniGenei Gma.17605.

    3D structure databases

    ProteinModelPortali P24826.
    SMRi P24826. Positions 3-388.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi GLYMA08G11620.1 ; GLYMA08G11620.1 ; GLYMA08G11620 .
    GeneIDi 732575.
    KEGGi gmx:732575.

    Phylogenomic databases

    KOi K00660.
    OMAi QVEKPLF.

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Gene expression databases

    Genevestigatori P24826.

    Family and domain databases

    Gene3Di 3.40.47.10. 2 hits.
    InterProi IPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000451. PKS_III. 1 hit.
    SUPFAMi SSF53901. SSF53901. 2 hits.
    PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of gene 1 of the soybean chalcone synthase multigene family."
      Akada S., Kung S.D., Dube S.K.
      Plant Mol. Biol. 16:751-752(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. Williams.

    Entry informationi

    Entry nameiCHS1_SOYBN
    AccessioniPrimary (citable) accession number: P24826
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 1992
    Last sequence update: March 1, 1992
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3