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P24824

- CHS1_MAIZE

UniProt

P24824 - CHS1_MAIZE

Protein

Chalcone synthase WHP1

Gene

WHP1

Organism
Zea mays (Maize)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Mar 1992)
      Previous versions | rss
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    Functioni

    The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei167 – 1671PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. auxin polar transport Source: EnsemblPlants/Gramene
    2. flavonoid biosynthetic process Source: UniProtKB-UniPathway
    3. regulation of anthocyanin biosynthetic process Source: EnsemblPlants/Gramene
    4. response to auxin Source: EnsemblPlants/Gramene
    5. response to gravity Source: EnsemblPlants/Gramene
    6. response to jasmonic acid Source: EnsemblPlants/Gramene
    7. response to oxidative stress Source: EnsemblPlants/Gramene
    8. response to UV-B Source: EnsemblPlants/Gramene
    9. response to wounding Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chalcone synthase WHP1 (EC:2.3.1.74)
    Alternative name(s):
    Naringenin-chalcone synthase WHP1
    White pollen
    Gene namesi
    Name:WHP1
    OrganismiZea mays (Maize)
    Taxonomic identifieri4577 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

    Organism-specific databases

    GrameneiP24824.
    MaizeGDBi13853.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: EnsemblPlants/Gramene
    2. nucleus Source: EnsemblPlants/Gramene
    3. plant-type vacuole membrane Source: EnsemblPlants/Gramene

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 400400Chalcone synthase WHP1PRO_0000216003Add
    BLAST

    Proteomic databases

    PRIDEiP24824.

    Structurei

    3D structure databases

    ProteinModelPortaliP24824.
    SMRiP24824. Positions 7-392.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chalcone/stilbene synthases family.Curated

    Family and domain databases

    Gene3Di3.40.47.10. 2 hits.
    InterProiIPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000451. PKS_III. 1 hit.
    SUPFAMiSSF53901. SSF53901. 2 hits.
    PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P24824-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGATVTVDE VRKGQRATGP ATVLAIGTAT PANCVYQADY PDYYFRITKS    50
    DHLTDLKEKF KRMCDKSMIR KRYMHLTEEF LSENPSMCAY MAPSLDARQD 100
    VVVTEVPKLG KAAAQEAIKE WGQPKSRITH LVFCTTSGVD MPGADYQLTK 150
    ALGLRVVNRL MMYQQGCFAG GTVLRVAKDV AENNRGARVM VVCSEITAVT 200
    FRGPSESHVD SLVGQALFGD GAAAGRGGAD PDGRVERPLF QLVSAAQTIL 250
    PDSEGAIDGH LREVGLAFHL LKDVPGLISK NIERALEDAF EPLGISDWNS 300
    IFWVAHPGGP AILDQVEAKV GLDKARMRAT RHVLSEYGNM SSACVLFILD 350
    EMRKRPAEDG QSTTGEGLDW GVLFGFGPGL TVETVVLHSV PITTGAPTAA 400
    Length:400
    Mass (Da):43,172
    Last modified:March 1, 1992 - v1
    Checksum:i8AB661A86253616C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60204 Genomic DNA. Translation: CAA42763.1.
    PIRiS16599. SYZMW1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60204 Genomic DNA. Translation: CAA42763.1 .
    PIRi S16599. SYZMW1.

    3D structure databases

    ProteinModelPortali P24824.
    SMRi P24824. Positions 7-392.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P24824.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    Gramenei P24824.
    MaizeGDBi 13853.

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Family and domain databases

    Gene3Di 3.40.47.10. 2 hits.
    InterProi IPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000451. PKS_III. 1 hit.
    SUPFAMi SSF53901. SSF53901. 2 hits.
    PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The duplicated chalcone synthase genes C2 and Whp (white pollen) of Zea mays are independently regulated; evidence for translational control of Whp expression by the anthocyanin intensifying gene in."
      Franken P., Niesbach-Kloesgen U., Weydemann U., Marechal-Drouard L., Saedler H., Wienand U.
      EMBO J. 10:2605-2612(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. Line C1-P.
      Tissue: Leaf.

    Entry informationi

    Entry nameiCHS1_MAIZE
    AccessioniPrimary (citable) accession number: P24824
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 1992
    Last sequence update: March 1, 1992
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3