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P24824

- CHS1_MAIZE

UniProt

P24824 - CHS1_MAIZE

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Protein
Chalcone synthase WHP1
Gene
WHP1
Organism
Zea mays (Maize)
Status
Reviewed - Annotation score: 4 out of 5 - Protein inferred from homologyi

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei167 – 1671 By similarity

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. auxin polar transport Source: EnsemblPlants/Gramene
  2. flavonoid biosynthetic process Source: UniProtKB-UniPathway
  3. regulation of anthocyanin biosynthetic process Source: EnsemblPlants/Gramene
  4. response to UV-B Source: EnsemblPlants/Gramene
  5. response to auxin Source: EnsemblPlants/Gramene
  6. response to gravity Source: EnsemblPlants/Gramene
  7. response to jasmonic acid Source: EnsemblPlants/Gramene
  8. response to oxidative stress Source: EnsemblPlants/Gramene
  9. response to wounding Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase WHP1 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase WHP1
White pollen
Gene namesi
Name:WHP1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Organism-specific databases

GrameneiP24824.
MaizeGDBi13853.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: EnsemblPlants/Gramene
  2. nucleus Source: EnsemblPlants/Gramene
  3. plant-type vacuole membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Chalcone synthase WHP1
PRO_0000216003Add
BLAST

Proteomic databases

PRIDEiP24824.

Structurei

3D structure databases

ProteinModelPortaliP24824.
SMRiP24824. Positions 7-392.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24824-1 [UniParc]FASTAAdd to Basket

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MAGATVTVDE VRKGQRATGP ATVLAIGTAT PANCVYQADY PDYYFRITKS    50
DHLTDLKEKF KRMCDKSMIR KRYMHLTEEF LSENPSMCAY MAPSLDARQD 100
VVVTEVPKLG KAAAQEAIKE WGQPKSRITH LVFCTTSGVD MPGADYQLTK 150
ALGLRVVNRL MMYQQGCFAG GTVLRVAKDV AENNRGARVM VVCSEITAVT 200
FRGPSESHVD SLVGQALFGD GAAAGRGGAD PDGRVERPLF QLVSAAQTIL 250
PDSEGAIDGH LREVGLAFHL LKDVPGLISK NIERALEDAF EPLGISDWNS 300
IFWVAHPGGP AILDQVEAKV GLDKARMRAT RHVLSEYGNM SSACVLFILD 350
EMRKRPAEDG QSTTGEGLDW GVLFGFGPGL TVETVVLHSV PITTGAPTAA 400
Length:400
Mass (Da):43,172
Last modified:March 1, 1992 - v1
Checksum:i8AB661A86253616C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X60204 Genomic DNA. Translation: CAA42763.1.
PIRiS16599. SYZMW1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X60204 Genomic DNA. Translation: CAA42763.1 .
PIRi S16599. SYZMW1.

3D structure databases

ProteinModelPortali P24824.
SMRi P24824. Positions 7-392.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P24824.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei P24824.
MaizeGDBi 13853.

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The duplicated chalcone synthase genes C2 and Whp (white pollen) of Zea mays are independently regulated; evidence for translational control of Whp expression by the anthocyanin intensifying gene in."
    Franken P., Niesbach-Kloesgen U., Weydemann U., Marechal-Drouard L., Saedler H., Wienand U.
    EMBO J. 10:2605-2612(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Line C1-P.
    Tissue: Leaf.

Entry informationi

Entry nameiCHS1_MAIZE
AccessioniPrimary (citable) accession number: P24824
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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