Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P24824 (CHS1_MAIZE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chalcone synthase WHP1

EC=2.3.1.74
Alternative name(s):
Naringenin-chalcone synthase WHP1
White pollen
Gene names
Name:WHP1
OrganismZea mays (Maize)
Taxonomic identifier4577 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activity

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathway

Secondary metabolite biosynthesis; flavonoid biosynthesis.

Sequence similarities

Belongs to the chalcone/stilbene synthases family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Chalcone synthase WHP1
PRO_0000216003

Sites

Active site1671 By similarity

Sequences

Sequence LengthMass (Da)Tools
P24824 [UniParc].

Last modified March 1, 1992. Version 1.
Checksum: 8AB661A86253616C

FASTA40043,172
        10         20         30         40         50         60 
MAGATVTVDE VRKGQRATGP ATVLAIGTAT PANCVYQADY PDYYFRITKS DHLTDLKEKF 

        70         80         90        100        110        120 
KRMCDKSMIR KRYMHLTEEF LSENPSMCAY MAPSLDARQD VVVTEVPKLG KAAAQEAIKE 

       130        140        150        160        170        180 
WGQPKSRITH LVFCTTSGVD MPGADYQLTK ALGLRVVNRL MMYQQGCFAG GTVLRVAKDV 

       190        200        210        220        230        240 
AENNRGARVM VVCSEITAVT FRGPSESHVD SLVGQALFGD GAAAGRGGAD PDGRVERPLF 

       250        260        270        280        290        300 
QLVSAAQTIL PDSEGAIDGH LREVGLAFHL LKDVPGLISK NIERALEDAF EPLGISDWNS 

       310        320        330        340        350        360 
IFWVAHPGGP AILDQVEAKV GLDKARMRAT RHVLSEYGNM SSACVLFILD EMRKRPAEDG 

       370        380        390        400 
QSTTGEGLDW GVLFGFGPGL TVETVVLHSV PITTGAPTAA 

« Hide

References

[1]"The duplicated chalcone synthase genes C2 and Whp (white pollen) of Zea mays are independently regulated; evidence for translational control of Whp expression by the anthocyanin intensifying gene in."
Franken P., Niesbach-Kloesgen U., Weydemann U., Marechal-Drouard L., Saedler H., Wienand U.
EMBO J. 10:2605-2612(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Line C1-P.
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X60204 Genomic DNA. Translation: CAA42763.1.
PIRSYZMW1. S16599.

3D structure databases

ProteinModelPortalP24824.
SMRP24824. Positions 7-392.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP24824.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneP24824.
MaizeGDB13853.

Enzyme and pathway databases

UniPathwayUPA00154.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFPIRSF000451. PKS_III. 1 hit.
SUPFAMSSF53901. SSF53901. 2 hits.
PROSITEPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHS1_MAIZE
AccessionPrimary (citable) accession number: P24824
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways