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P24824

- CHS1_MAIZE

UniProt

P24824 - CHS1_MAIZE

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Protein

Chalcone synthase WHP1

Gene

WHP1

Organism
Zea mays (Maize)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei167 – 1671PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase WHP1 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase WHP1
White pollen
Gene namesi
Name:WHP1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Organism-specific databases

GrameneiP24824.
MaizeGDBi13853.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Chalcone synthase WHP1PRO_0000216003Add
BLAST

Proteomic databases

PRIDEiP24824.

Structurei

3D structure databases

ProteinModelPortaliP24824.
SMRiP24824. Positions 7-392.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24824-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAGATVTVDE VRKGQRATGP ATVLAIGTAT PANCVYQADY PDYYFRITKS
60 70 80 90 100
DHLTDLKEKF KRMCDKSMIR KRYMHLTEEF LSENPSMCAY MAPSLDARQD
110 120 130 140 150
VVVTEVPKLG KAAAQEAIKE WGQPKSRITH LVFCTTSGVD MPGADYQLTK
160 170 180 190 200
ALGLRVVNRL MMYQQGCFAG GTVLRVAKDV AENNRGARVM VVCSEITAVT
210 220 230 240 250
FRGPSESHVD SLVGQALFGD GAAAGRGGAD PDGRVERPLF QLVSAAQTIL
260 270 280 290 300
PDSEGAIDGH LREVGLAFHL LKDVPGLISK NIERALEDAF EPLGISDWNS
310 320 330 340 350
IFWVAHPGGP AILDQVEAKV GLDKARMRAT RHVLSEYGNM SSACVLFILD
360 370 380 390 400
EMRKRPAEDG QSTTGEGLDW GVLFGFGPGL TVETVVLHSV PITTGAPTAA
Length:400
Mass (Da):43,172
Last modified:March 1, 1992 - v1
Checksum:i8AB661A86253616C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60204 Genomic DNA. Translation: CAA42763.1.
PIRiS16599. SYZMW1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60204 Genomic DNA. Translation: CAA42763.1 .
PIRi S16599. SYZMW1.

3D structure databases

ProteinModelPortali P24824.
SMRi P24824. Positions 7-392.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P24824.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei P24824.
MaizeGDBi 13853.

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The duplicated chalcone synthase genes C2 and Whp (white pollen) of Zea mays are independently regulated; evidence for translational control of Whp expression by the anthocyanin intensifying gene in."
    Franken P., Niesbach-Kloesgen U., Weydemann U., Marechal-Drouard L., Saedler H., Wienand U.
    EMBO J. 10:2605-2612(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Line C1-P.
    Tissue: Leaf.

Entry informationi

Entry nameiCHS1_MAIZE
AccessioniPrimary (citable) accession number: P24824
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: October 29, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3