P24669 (SODC_PINSY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn]
EC=1.15.1.1

Gene names

Name:

SODCC

Organism

Pinus sylvestris (Scots pine)

Taxonomic identifier

3349 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Coniferophyta › Coniferopsida › Coniferales › Pinaceae › Pinus › Pinus

Protein attributes

Sequence length	154 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homodimer.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 154	154	Superoxide dismutase [Cu-Zn]		PRO_0000164154
Sites
	Metal binding	47	1	Copper; catalytic By similarity
	Metal binding	49	1	Copper; catalytic By similarity
	Metal binding	64	1	Copper; catalytic By similarity
	Metal binding	64	1	Zinc; structural By similarity
	Metal binding	72	1	Zinc; structural By similarity
	Metal binding	81	1	Zinc; structural By similarity
	Metal binding	84	1	Zinc; structural By similarity
	Metal binding	121	1	Copper; catalytic By similarity
Amino acid modifications
	Disulfide bond	58 ↔ 147		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P24669 [UniParc]. Last modified March 1, 1992. Version 1. Checksum: A2353EE52B4BE58F	FASTA	154	15,376
	10 20 30 40 50 60 MGLLKAVVVL NGAADVKGVV QFTQEGDGPT TVTGKISGLS PGLHGFHVHA LGDTTNGCMS 70 80 90 100 110 120 TGPHFNPLGK EHGAPTDDNR HAGDLGNVTV GTDGTVEFSI TDSQIPLSGP HSIVGRAVVV 130 140 150 HADPDDLGKG GHELSKSTGN AGGRLACGVV GLQG

References

[1]	"Characterization of cDNAs encoding CuZn-superoxide dismutases in Scots pine." Karpinski S., Wingsle G., Olsson O., Haellgren J.E. Plant Mol. Biol. 18:545-555(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Seedling.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X58578 mRNA. Translation: CAA41454.1.
PIR	S20511.
3D structure databases
ProteinModelPortal	P24669.
SMR	P24669. Positions 3-154.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODC_PINSY

Accession

Primary (citable) accession number: P24669

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 1992
Last sequence update:	March 1, 1992
Last modified:	April 3, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program