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Protein

Type-2 restriction enzyme NgoPII

Gene

ngoPIIR

Organism
Neisseria gonorrhoeae
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Recognizes the double-stranded sequence GGCC and cleaves after G-2.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processRestriction system

Protein family/group databases

REBASEi1331 NgoPII

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme NgoPII (EC:3.1.21.4)
Short name:
R.NgoPII
Alternative name(s):
Endonuclease NgoPII
Type II restriction enzyme NgoPII
Gene namesi
Name:ngoPIIR
Synonyms:dcrB
OrganismiNeisseria gonorrhoeae
Taxonomic identifieri485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000773481 – 278Type-2 restriction enzyme NgoPIIAdd BLAST278

Structurei

3D structure databases

SMRiP24617
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108PPJ Bacteria
ENOG410ZYDD LUCA

Family and domain databases

InterProiView protein in InterPro
IPR019046 Restrct_endonuc_II_NgoPII
PfamiView protein in Pfam
PF09521 RE_NgoPII, 1 hit

Sequencei

Sequence statusi: Complete.

P24617-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIIDAIINL ANNPVVGVES HSQSNNRANQ AGDALEEYVK DLFSGSFNLN
60 70 80 90 100
ETQRIARHAK VFSYLGNNSN PPDAMLRNGD AIEVKKIESK DSALALNSSH
110 120 130 140 150
PKSKLSVDDS MLTKACKDAE KWEEKDIIYI VGVVDKKKNL KHLAMVYGID
160 170 180 190 200
YCADAECYLK IKNQIKEGIG NIGGIQFAET KELGRVNRID PLNITYLRVR
210 220 230 240 250
GMWGIENPWF VFNYIYQRNM EKSFNFMAII NEDKWNSFNN TDKLLAIQDS
260 270
KLAISDIKIK NPNNPARLRN AKLITYHL
Length:278
Mass (Da):31,501
Last modified:March 1, 1992 - v1
Checksum:i1BF8B25BEEC96903
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52661 Genomic DNA Translation: CAA36887.1
PIRiS04419
RefSeqiWP_003690022.1, NZ_PTPT01000006.1

Similar proteinsi

Entry informationi

Entry nameiT2P2_NEIGO
AccessioniPrimary (citable) accession number: P24617
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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