Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Type-2 restriction enzyme NgoPII

Gene

ngoPIIR

Organism
Neisseria gonorrhoeae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Recognizes the double-stranded sequence GGCC and cleaves after G-2.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. Type II site-specific deoxyribonuclease activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA restriction-modification system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Restriction system

Protein family/group databases

REBASEi1331. NgoPII.

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme NgoPII (EC:3.1.21.4)
Short name:
R.NgoPII
Alternative name(s):
Endonuclease NgoPII
Type II restriction enzyme NgoPII
Gene namesi
Name:ngoPIIR
Synonyms:dcrB
OrganismiNeisseria gonorrhoeae
Taxonomic identifieri485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 278278Type-2 restriction enzyme NgoPIIPRO_0000077348Add
BLAST

Family & Domainsi

Family and domain databases

InterProiIPR019046. Restrct_endonuc_II_NgoPII.
[Graphical view]
PfamiPF09521. RE_NgoPII. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24617-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIIDAIINL ANNPVVGVES HSQSNNRANQ AGDALEEYVK DLFSGSFNLN
60 70 80 90 100
ETQRIARHAK VFSYLGNNSN PPDAMLRNGD AIEVKKIESK DSALALNSSH
110 120 130 140 150
PKSKLSVDDS MLTKACKDAE KWEEKDIIYI VGVVDKKKNL KHLAMVYGID
160 170 180 190 200
YCADAECYLK IKNQIKEGIG NIGGIQFAET KELGRVNRID PLNITYLRVR
210 220 230 240 250
GMWGIENPWF VFNYIYQRNM EKSFNFMAII NEDKWNSFNN TDKLLAIQDS
260 270
KLAISDIKIK NPNNPARLRN AKLITYHL
Length:278
Mass (Da):31,501
Last modified:February 29, 1992 - v1
Checksum:i1BF8B25BEEC96903
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52661 Genomic DNA. Translation: CAA36887.1.
PIRiS04419.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52661 Genomic DNA. Translation: CAA36887.1.
PIRiS04419.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

REBASEi1331. NgoPII.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR019046. Restrct_endonuc_II_NgoPII.
[Graphical view]
PfamiPF09521. RE_NgoPII. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide sequence and genetic organization of the NgoPII restriction-modification system of Neisseria gonorrhoeae."
    Sullivan K.M., Saunders J.R.
    Mol. Gen. Genet. 216:380-387(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: P9.

Entry informationi

Entry nameiT2P2_NEIGO
AccessioniPrimary (citable) accession number: P24617
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 29, 1992
Last sequence update: February 29, 1992
Last modified: April 15, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.