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Protein

Twitching mobility protein

Gene

pilT

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in pilus retraction.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi130 – 137ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

  • pilus retraction Source: PseudoCAP
  • transport Source: UniProtKB-KW
  • type IV pilus-dependent motility Source: PseudoCAP
Complete GO annotation...

Keywords - Biological processi

Fimbrium biogenesis, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Protein family/group databases

TCDBi3.A.15.2.1. the outer membrane protein secreting main terminal branch (mtb) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Twitching mobility protein
Gene namesi
Name:pilT
Ordered Locus Names:PA0395
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA0395.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB-SubCell
  • type IV pilus Source: PseudoCAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002072961 – 344Twitching mobility proteinAdd BLAST344

Proteomic databases

PaxDbiP24559.
PRIDEiP24559.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA0395.

Structurei

Secondary structure

1344
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 12Combined sources10
Beta strandi16 – 21Combined sources6
Beta strandi27 – 30Combined sources4
Beta strandi33 – 36Combined sources4
Helixi44 – 54Combined sources11
Helixi57 – 66Combined sources10
Beta strandi69 – 75Combined sources7
Turni76 – 78Combined sources3
Beta strandi79 – 88Combined sources10
Beta strandi91 – 99Combined sources9
Turni106 – 110Combined sources5
Helixi113 – 120Combined sources8
Beta strandi122 – 129Combined sources8
Helixi136 – 150Combined sources15
Beta strandi154 – 161Combined sources8
Beta strandi169 – 177Combined sources9
Turni178 – 180Combined sources3
Beta strandi181 – 183Combined sources3
Helixi185 – 192Combined sources8
Beta strandi198 – 203Combined sources6
Helixi208 – 219Combined sources12
Beta strandi223 – 229Combined sources7
Helixi233 – 242Combined sources10
Helixi246 – 259Combined sources14
Beta strandi260 – 269Combined sources10
Beta strandi277 – 284Combined sources8
Helixi287 – 295Combined sources9
Helixi298 – 300Combined sources3
Helixi301 – 306Combined sources6
Helixi309 – 311Combined sources3
Helixi316 – 320Combined sources5
Helixi331 – 336Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3JVUX-ray3.10A/B/C1-344[»]
3JVVX-ray2.60A/B/C1-344[»]
ProteinModelPortaliP24559.
SMRiP24559.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP24559.

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP E family.Curated

Phylogenomic databases

eggNOGiENOG4105CZX. Bacteria.
COG2805. LUCA.
InParanoidiP24559.
KOiK02669.
OMAiVSPMIRV.
PhylomeDBiP24559.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR006321. PilT.
IPR001482. T2SS_protein-E.
[Graphical view]
PfamiPF00437. T2SSE. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01420. pilT_fam. 1 hit.
PROSITEiPS00662. T2SP_E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24559-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDITELLAFS AKQGASDLHL SAGLPPMIRV DGDVRRINLP PLEHKQVHAL
60 70 80 90 100
IYDIMNDKQR KDFEEFLETD FSFEVPGVAR FRVNAFNQNR GAGAVFRTIP
110 120 130 140 150
SKVLTMEELG MGEVFKRVSD VPRGLVLVTG PTGSGKSTTL AAMLDYLNNT
160 170 180 190 200
KYHHILTIED PIEFVHESKK CLVNQREVHR DTLGFSEALR SALREDPDII
210 220 230 240 250
LVGEMRDLET IRLALTAAET GHLVFGTLHT TSAAKTIDRV VDVFPAEEKA
260 270 280 290 300
MVRSMLSESL QSVISQTLIK KIGGGRVAAH EIMIGTPAIR NLIREDKVAQ
310 320 330 340
MYSAIQTGGS LGMQTLDMCL KGLVAKGLIS RENAREKAKI PENF
Length:344
Mass (Da):38,021
Last modified:March 1, 1992 - v1
Checksum:iC35F89F28AD0BE01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55524 Genomic DNA. Translation: AAA25963.1.
AE004091 Genomic DNA. Translation: AAG03784.1.
PIRiJN0055.
RefSeqiNP_249086.1. NC_002516.2.
WP_003084552.1. NZ_ASJY01000077.1.

Genome annotation databases

EnsemblBacteriaiAAG03784; AAG03784; PA0395.
GeneIDi878389.
KEGGipae:PA0395.
PATRICi19835030. VBIPseAer58763_0416.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55524 Genomic DNA. Translation: AAA25963.1.
AE004091 Genomic DNA. Translation: AAG03784.1.
PIRiJN0055.
RefSeqiNP_249086.1. NC_002516.2.
WP_003084552.1. NZ_ASJY01000077.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3JVUX-ray3.10A/B/C1-344[»]
3JVVX-ray2.60A/B/C1-344[»]
ProteinModelPortaliP24559.
SMRiP24559.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA0395.

Protein family/group databases

TCDBi3.A.15.2.1. the outer membrane protein secreting main terminal branch (mtb) family.

Proteomic databases

PaxDbiP24559.
PRIDEiP24559.

Protocols and materials databases

DNASUi878389.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG03784; AAG03784; PA0395.
GeneIDi878389.
KEGGipae:PA0395.
PATRICi19835030. VBIPseAer58763_0416.

Organism-specific databases

PseudoCAPiPA0395.

Phylogenomic databases

eggNOGiENOG4105CZX. Bacteria.
COG2805. LUCA.
InParanoidiP24559.
KOiK02669.
OMAiVSPMIRV.
PhylomeDBiP24559.

Miscellaneous databases

EvolutionaryTraceiP24559.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR006321. PilT.
IPR001482. T2SS_protein-E.
[Graphical view]
PfamiPF00437. T2SSE. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01420. pilT_fam. 1 hit.
PROSITEiPS00662. T2SP_E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPILT_PSEAE
AccessioniPrimary (citable) accession number: P24559
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: November 2, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.