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P24468 (COT2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 150. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
COUP transcription factor 2

Short name=COUP-TF2
Alternative name(s):
Apolipoprotein A-I regulatory protein 1
Short name=ARP-1
COUP transcription factor II
Short name=COUP-TF II
Nuclear receptor subfamily 2 group F member 2
Gene names
Name:NR2F2
Synonyms:ARP1, TFCOUP2
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length414 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. Ref.1 Ref.11 Ref.14

Subunit structure

Interacts with SQSTM1 By similarity. Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2 By similarity. Ref.1 Ref.12 Ref.14

Subcellular location

Nucleus.

Tissue specificity

Ubiquitous.

Sequence similarities

Belongs to the nuclear hormone receptor family. NR2 subfamily.

Contains 1 nuclear receptor DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   Coding sequence diversityAlternative splicing
   DomainZinc-finger
   LigandDNA-binding
Metal-binding
Zinc
   Molecular functionActivator
Receptor
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processanterior/posterior pattern specification

Inferred from electronic annotation. Source: Ensembl

blood vessel morphogenesis

Inferred from electronic annotation. Source: Ensembl

fertilization

Inferred from electronic annotation. Source: Ensembl

forebrain development

Inferred from electronic annotation. Source: Ensembl

intracellular receptor signaling pathway

Inferred from direct assay Ref.14. Source: GOC

limb development

Inferred from electronic annotation. Source: Ensembl

lipid metabolic process

Traceable author statement Ref.1. Source: ProtInc

maternal placenta development

Inferred from electronic annotation. Source: Ensembl

negative regulation of cyclin-dependent protein serine/threonine kinase activity

Inferred from direct assay PubMed 19210544. Source: BHF-UCL

negative regulation of endothelial cell migration

Inferred from mutant phenotype PubMed 19210544. Source: BHF-UCL

negative regulation of endothelial cell proliferation

Inferred from mutant phenotype PubMed 19210544. Source: BHF-UCL

negative regulation of transcription from RNA polymerase II promoter

Inferred from direct assay Ref.11. Source: UniProtKB

negative regulation of transcription, DNA-templated

Inferred from direct assay PubMed 19210544. Source: BHF-UCL

neuron migration

Inferred from electronic annotation. Source: Ensembl

placenta blood vessel development

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription, DNA-templated

Inferred from direct assay Ref.14. Source: UniProtKB

radial pattern formation

Inferred from electronic annotation. Source: Ensembl

regulation of transcription from RNA polymerase II promoter

Traceable author statement Ref.1. Source: ProtInc

regulation of transcription involved in lymphatic endothelial cell fate commitment

Inferred from mutant phenotype PubMed 18815287. Source: BHF-UCL

response to estradiol

Inferred from electronic annotation. Source: Ensembl

signal transduction

Traceable author statement Ref.1. Source: ProtInc

skeletal muscle tissue development

Inferred from electronic annotation. Source: Ensembl

trophoblast giant cell differentiation

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentnucleus

Inferred from direct assay PubMed 19210544. Source: BHF-UCL

   Molecular_functionligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity

Inferred from direct assay Ref.14. Source: UniProtKB

protein binding

Inferred from physical interaction Ref.14. Source: UniProtKB

protein homodimerization activity

Inferred from physical interaction Ref.14. Source: UniProtKB

retinoic acid binding

Inferred from direct assay Ref.14. Source: UniProtKB

sequence-specific DNA binding

Inferred from direct assay Ref.11. Source: UniProtKB

sequence-specific DNA binding transcription factor activity

Inferred from direct assay Ref.11. Source: UniProtKB

steroid hormone receptor activity

Inferred from electronic annotation. Source: InterPro

transcription corepressor activity

Traceable author statement Ref.1. Source: ProtInc

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: P24468-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: P24468-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-147: MAMVVSTWRD...KCLKVGMRRE → MQAVWDLEQGKYGF
Isoform 3 (identifier: P24468-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-153: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 414414COUP transcription factor 2
PRO_0000053606

Regions

DNA binding76 – 15176Nuclear receptor Ref.3
Zinc finger79 – 9921NR C4-type
Zinc finger115 – 13925NR C4-type
Region117 – 414298Interaction with ZFPM2 By similarity
Region183 – 414232Ligand-binding By similarity
Region337 – 41478Important for dimerization
Compositional bias71 – 755Poly-Gln

Natural variations

Alternative sequence1 – 153153Missing in isoform 3.
VSP_043897
Alternative sequence1 – 147147MAMVV…GMRRE → MQAVWDLEQGKYGF in isoform 2.
VSP_042630

Experimental info

Mutagenesis2281R → E: Reduces transcription activation by 40%; when associated with R-398. Ref.14
Mutagenesis2491W → A: Reduces transcription activation by 50%; when associated with A-250. Ref.14
Mutagenesis2501S → A: Reduces transcription activation by 50%; when associated with A-249. Ref.14
Mutagenesis2501S → W: Reduces transcription activation by 50%. Ref.14
Mutagenesis253 – 2542FV → AA: Reduces transcription activation by 50%.
Mutagenesis269 – 2702LL → AA: Reduces transcription activation by 50%.
Mutagenesis364 – 3652LL → AA: Reduces transcription activation by 80%.
Mutagenesis3981D → R: Reduces transcription activation by 40%; when associated with E-228. Ref.14

Secondary structure

........................... 414
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified March 1, 1992. Version 1.
Checksum: C24CB2E8C8A27E8C

FASTA41445,571
        10         20         30         40         50         60 
MAMVVSTWRD PQDEVPGSQG SQASQAPPVP GPPPGAPHTP QTPGQGGPAS TPAQTAAGGQ 

        70         80         90        100        110        120 
GGPGGPGSDK QQQQQHIECV VCGDKSSGKH YGQFTCEGCK SFFKRSVRRN LSYTCRANRN 

       130        140        150        160        170        180 
CPIDQHHRNQ CQYCRLKKCL KVGMRREAVQ RGRMPPTQPT HGQFALTNGD PLNCHSYLSG 

       190        200        210        220        230        240 
YISLLLRAEP YPTSRFGSQC MQPNNIMGIE NICELAARML FSAVEWARNI PFFPDLQITD 

       250        260        270        280        290        300 
QVALLRLTWS ELFVLNAAQC SMPLHVAPLL AAAGLHASPM SADRVVAFMD HIRIFQEQVE 

       310        320        330        340        350        360 
KLKALHVDSA EYSCLKAIVL FTSDACGLSD VAHVESLQEK SQCALEEYVR SQYPNQPTRF 

       370        380        390        400        410 
GKLLLRLPSL RTVSSSVIEQ LFFVRLVGKT PIETLIRDML LSGSSFNWPY MAIQ 

« Hide

Isoform 2 [UniParc].

Checksum: 038DD27B80868BB5
Show »

FASTA28131,484
Isoform 3 [UniParc].

Checksum: 5526AD057E2A639E
Show »

FASTA26129,163

References

« Hide 'large scale' references
[1]"Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily."
Ladias J.A.A., Karathanasis S.K.
Science 251:561-565(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, SUBUNIT.
[2]Speckmayer R.W.M., Paulweber B., Sandhofer F.
Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system."
Kobayashi T., Kodani Y., Nozawa A., Endo Y., Sawasaki T.
FEBS Lett. 582:2737-2744(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), DNA-BINDING.
[4]"Characterisation of a new, DNA binding domain deficient chicken ovalbumin upstream promoter- transcription factor IIdelta isoform in the human brain."
Schote A.B., Bechet T., Pirrotte P., Turner J.D., Muller C.P.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
Tissue: Liver.
[5]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
Tissue: Mammary gland.
[6]"Isolation of cDNA coding for multiple human nuclear receptor clones."
Kaighin V.A., Martin A.L., Aronstam R.S.
Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
Tissue: Kidney.
[7]"Analysis of the DNA sequence and duplication history of human chromosome 15."
Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. expand/collapse author list , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[8]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[9]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
Tissue: Brain, Kidney and Spleen.
[10]"The COUP-TFs compose a family of functionally related transcription factors."
Wang L.H., Ing N.H., Tsai S.Y., O'Malley B.W., Tsai M.J.
Gene Expr. 1:207-216(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-351 (ISOFORM 1).
[11]"The nuclear orphan receptors COUP-TFII and Ear-2 act as silencers of the human oxytocin gene promoter."
Chu K., Zingg H.H.
J. Mol. Endocrinol. 19:163-172(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[12]"Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2."
Avram D., Ishmael J.E., Nevrivy D.J., Peterson V.J., Lee S.H., Dowell P., Leid M.
J. Biol. Chem. 274:14331-14336(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBUNIT, INTERACTION WITH NR2F6.
[13]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[14]"Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor."
Kruse S.W., Suino-Powell K., Zhou X.E., Kretschman J.E., Reynolds R., Vonrhein C., Xu Y., Wang L., Tsai S.Y., Tsai M.J., Xu H.E.
PLoS Biol. 6:E227-E227(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.48 ANGSTROMS) OF 175-414, FUNCTION, SUBUNIT, INTERACTION WITH NCOA1; NCOA2; NCOA3 AND PPARGC1A, MUTAGENESIS OF ARG-228; TRP-249; SER-250; 253-PHE-VAL-254; 260-LEU-LEU-270; 364-LEU-LEU-365 AND ASP-398.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M64497 mRNA. Translation: AAA86429.1.
U60477 Genomic DNA. Translation: AAB09475.1.
AB307711 mRNA. Translation: BAH02302.1.
FM208183 mRNA. Translation: CAR63888.1.
AK298824 mRNA. Translation: BAG60954.1.
AK301595 mRNA. Translation: BAG63083.1.
AK316086 mRNA. Translation: BAH14457.1.
HQ692849 mRNA. Translation: ADZ17360.1.
HQ692850 mRNA. Translation: ADZ17361.1.
AC016251 Genomic DNA. No translation available.
CH471101 Genomic DNA. Translation: EAX02195.1.
CH471101 Genomic DNA. Translation: EAX02196.1.
CH471101 Genomic DNA. Translation: EAX02197.1.
BC014664 mRNA. Translation: AAH14664.1.
BC042897 mRNA. Translation: AAH42897.1.
BC106083 mRNA. Translation: AAI06084.1.
M62760 mRNA. Translation: AAA21479.1.
CCDSCCDS10375.1. [P24468-1]
CCDS45358.1. [P24468-2]
CCDS45359.1. [P24468-3]
PIRA37133.
RefSeqNP_001138627.1. NM_001145155.1. [P24468-2]
NP_001138628.1. NM_001145156.1. [P24468-3]
NP_001138629.1. NM_001145157.1. [P24468-3]
NP_066285.1. NM_021005.3. [P24468-1]
UniGeneHs.347991.
Hs.519445.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3CJWX-ray1.48A175-414[»]
ProteinModelPortalP24468.
SMRP24468. Positions 75-407.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid112884. 16 interactions.
DIPDIP-29713N.
IntActP24468. 8 interactions.
MINTMINT-1183332.
STRING9606.ENSP00000329908.

Chemistry

ChEMBLCHEMBL1961790.

PTM databases

PhosphoSiteP24468.

Polymorphism databases

DMDM114203.

Proteomic databases

MaxQBP24468.
PaxDbP24468.
PRIDEP24468.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000394166; ENSP00000377721; ENSG00000185551. [P24468-1]
ENST00000394171; ENSP00000377726; ENSG00000185551. [P24468-3]
ENST00000421109; ENSP00000401674; ENSG00000185551. [P24468-2]
ENST00000453270; ENSP00000389853; ENSG00000185551. [P24468-3]
GeneID7026.
KEGGhsa:7026.
UCSCuc002btp.3. human. [P24468-2]
uc010uri.2. human. [P24468-1]

Organism-specific databases

CTD7026.
GeneCardsGC15P096869.
HGNCHGNC:7976. NR2F2.
MIM107773. gene.
neXtProtNX_P24468.
PharmGKBPA31759.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG327099.
HOGENOMHOG000260820.
HOVERGENHBG005606.
InParanoidP24468.
KOK08548.
OMAGPPNNTQ.
OrthoDBEOG72RMZ5.
PhylomeDBP24468.
TreeFamTF352097.

Enzyme and pathway databases

SignaLinkP24468.

Gene expression databases

ArrayExpressP24468.
BgeeP24468.
CleanExHS_NR2F2.
GenevestigatorP24468.

Family and domain databases

Gene3D1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProIPR003068. COUP_TF.
IPR008946. Nucl_hormone_rcpt_ligand-bd.
IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
IPR001723. Str_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSPR01282. COUPTNFACTOR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMSSF48508. SSF48508. 1 hit.
PROSITEPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP24468.
GeneWikiCOUP-TFII.
GenomeRNAi7026.
NextBio27451.
PROP24468.
SOURCESearch...

Entry information

Entry nameCOT2_HUMAN
AccessionPrimary (citable) accession number: P24468
Secondary accession number(s): B4DQJ2 expand/collapse secondary AC list , B6ZGU1, Q03754, Q3KQR7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: July 9, 2014
This is version 150 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 15

Human chromosome 15: entries, gene names and cross-references to MIM