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Protein

Capsid vertex component 1

Gene

CVC1

Organism
Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.UniRule annotation

GO - Biological processi

Keywordsi

Biological processViral genome packaging, Viral release from host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid vertex component 1UniRule annotation
Gene namesi
Name:CVC1UniRule annotation
Ordered Locus Names:10R, U64
OrganismiHuman herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus)
Taxonomic identifieri10370 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeBetaherpesvirinaeRoseolovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000009295 Componenti: Genome

Subcellular locationi

P24441:
  • Virion UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001159591 – 442Capsid vertex component 1Add BLAST442

Expressioni

Keywords - Developmental stagei

Late protein

Interactioni

Subunit structurei

Interacts (via C-terminus) with capsid vertex component 2/CVC2.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae CVC1 protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG09000094.

Family and domain databases

HAMAPiMF_04017. HSV_CVC1. 1 hit.
InterProiView protein in InterPro
IPR007640. UL17-like.
PfamiView protein in Pfam
PF04559. Herpes_UL17. 2 hits.

Sequencei

Sequence statusi: Complete.

P24441-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METHLYYDTL YQYQGGVYPA HICLPTDVCL PMRVDCIESL YFRCVFFKSG
60 70 80 90 100
MHYTEWSKLK FTVISREIKF KDVLKDADSD EVFTGLVVMT IPIPIVDFHF
110 120 130 140 150
DIDSVILKLV YPRLVHREIV LRLYDLICVR PPSNRPSEAS AKNIANDFYQ
160 170 180 190 200
LTSRENKQTP DEEKRCLFFQ QGPLEPPSTV RGLKAPGNEK PIQFPAHANE
210 220 230 240 250
KMTESFLSDS WFGQKVRCKK ILDFTQTYQV VVCWYELSFS REMQIENNLL
260 270 280 290 300
SASQLKRVNA ADFWDRTNRY LRDIGSRVLT HIVKTLQIHN RQFKQKFNCN
310 320 330 340 350
FPDNFSFDRL LSFMQLGKDF WILNLTLDSC IIKAIICFLG FQNGGKSFLA
360 370 380 390 400
QDEVWGDLID CSKGSVIYGE KIQWILDSTN NLYSTCREKQ NKSWELYVDC
410 420 430 440
CALYVSEKLE LDFVLPGGFA ITGKFALTDG DIDFFNWRFG LS
Length:442
Mass (Da):51,391
Last modified:March 1, 1992 - v1
Checksum:i9A5F3383DF05CDDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X83413 Genomic DNA. Translation: CAA58356.1.
M68963 Genomic DNA. Translation: AAA65573.1.
PIRiA36769.
RefSeqiNP_042957.1. NC_001664.2.

Genome annotation databases

GeneIDi1487946.
KEGGivg:1487946.

Similar proteinsi

Entry informationi

Entry nameiCVC1_HHV6U
AccessioniPrimary (citable) accession number: P24441
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: October 25, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families