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Protein

Zinc finger protein 239

Gene

Znf239

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri6 – 28C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri34 – 56C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri62 – 84C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri90 – 112C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri118 – 140C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri146 – 168C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri174 – 196C2H2-type 7PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 239
Short name:
Zfp-239
Alternative name(s):
Zinc finger protein MOK-2
Gene namesi
Name:Znf239
Synonyms:Mok-2, Mok2, Zfp239
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1306812. Zfp239.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000474811 – 201Zinc finger protein 239Add BLAST201

Proteomic databases

MaxQBiP24399.
PaxDbiP24399.
PRIDEiP24399.

PTM databases

iPTMnetiP24399.
PhosphoSitePlusiP24399.

Expressioni

Tissue specificityi

Preferentially expressed in transformed mouse cells.

Gene expression databases

BgeeiENSMUSG00000042097.
CleanExiMM_ZFP239.
GenevisibleiP24399. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078374.

Structurei

3D structure databases

ProteinModelPortaliP24399.
SMRiP24399.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri6 – 28C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri34 – 56C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri62 – 84C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri90 – 112C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri118 – 140C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri146 – 168C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri174 – 196C2H2-type 7PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00870000136464.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiP24399.
OMAiGCAREVE.
OrthoDBiEOG091G02KC.
PhylomeDBiP24399.
TreeFamiTF337055.

Family and domain databases

InterProiView protein in InterPro
IPR013087. Znf_C2H2_type.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 7 hits.
SUPFAMiSSF57667. SSF57667. 4 hits.
PROSITEiView protein in PROSITE
PS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.

Sequencei

Sequence statusi: Complete.

P24399-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKPYKCDK CGKGFTRSSS LLVHHSVHTG EKPFKCDRCG KGFSQSSKLH
60 70 80 90 100
IHKRVHTGEK PYACEECGMS FSQRSNLHIH QRVHTGERPY KCGECGKGFS
110 120 130 140 150
QSSNLHIHRC THTGEKPYQC YECGKGFSQS SDLRIHLRVH TGEKPYHCGK
160 170 180 190 200
CGQGFSQSSK LLIHQRVHTG EKPYECSKCG KGFSQSSNLH IHQRVHRKEL

H
Length:201
Mass (Da):22,818
Last modified:June 12, 2007 - v2
Checksum:iC7112D76DC7DC412
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti27V → L in AAA39729 (PubMed:2104662).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M32057 mRNA. Translation: AAA39729.1.
AK133328 mRNA. Translation: BAE21606.1.
BC003315 mRNA. Translation: AAH03315.1.
CCDSiCCDS20466.1.
PIRiI57505.
RefSeqiNP_001001792.1. NM_001001792.1.
NP_032642.2. NM_008616.2.
UniGeneiMm.249661.

Genome annotation databases

EnsembliENSMUST00000079405; ENSMUSP00000078374; ENSMUSG00000042097.
ENSMUST00000172088; ENSMUSP00000128270; ENSMUSG00000042097.
GeneIDi22685.
KEGGimmu:22685.
UCSCiuc009dlc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M32057 mRNA. Translation: AAA39729.1.
AK133328 mRNA. Translation: BAE21606.1.
BC003315 mRNA. Translation: AAH03315.1.
CCDSiCCDS20466.1.
PIRiI57505.
RefSeqiNP_001001792.1. NM_001001792.1.
NP_032642.2. NM_008616.2.
UniGeneiMm.249661.

3D structure databases

ProteinModelPortaliP24399.
SMRiP24399.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078374.

PTM databases

iPTMnetiP24399.
PhosphoSitePlusiP24399.

Proteomic databases

MaxQBiP24399.
PaxDbiP24399.
PRIDEiP24399.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000079405; ENSMUSP00000078374; ENSMUSG00000042097.
ENSMUST00000172088; ENSMUSP00000128270; ENSMUSG00000042097.
GeneIDi22685.
KEGGimmu:22685.
UCSCiuc009dlc.1. mouse.

Organism-specific databases

CTDi22685.
MGIiMGI:1306812. Zfp239.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00870000136464.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiP24399.
OMAiGCAREVE.
OrthoDBiEOG091G02KC.
PhylomeDBiP24399.
TreeFamiTF337055.

Miscellaneous databases

PROiPR:P24399.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000042097.
CleanExiMM_ZFP239.
GenevisibleiP24399. MM.

Family and domain databases

InterProiView protein in InterPro
IPR013087. Znf_C2H2_type.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 7 hits.
SUPFAMiSSF57667. SSF57667. 4 hits.
PROSITEiView protein in PROSITE
PS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiZN239_MOUSE
AccessioniPrimary (citable) accession number: P24399
Secondary accession number(s): Q99J71
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: June 12, 2007
Last modified: May 10, 2017
This is version 136 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.