SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P24399

- ZN239_MOUSE

UniProt

P24399 - ZN239_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Zinc finger protein 239
Gene
Znf239, Mok-2, Mok2, Zfp239
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri6 – 2823C2H2-type 1
Add
BLAST
Zinc fingeri34 – 5623C2H2-type 2
Add
BLAST
Zinc fingeri62 – 8423C2H2-type 3
Add
BLAST
Zinc fingeri90 – 11223C2H2-type 4
Add
BLAST
Zinc fingeri118 – 14023C2H2-type 5
Add
BLAST
Zinc fingeri146 – 16823C2H2-type 6
Add
BLAST
Zinc fingeri174 – 19623C2H2-type 7
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 239
Short name:
Zfp-239
Alternative name(s):
Zinc finger protein MOK-2
Gene namesi
Name:Znf239
Synonyms:Mok-2, Mok2, Zfp239
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 6

Organism-specific databases

MGIiMGI:1306812. Zfp239.

Subcellular locationi

Nucleus Reviewed prediction

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 201201Zinc finger protein 239
PRO_0000047481Add
BLAST

Proteomic databases

PRIDEiP24399.

PTM databases

PhosphoSiteiP24399.

Expressioni

Tissue specificityi

Preferentially expressed in transformed mouse cells.

Gene expression databases

BgeeiP24399.
CleanExiMM_ZFP239.
GenevestigatoriP24399.

Structurei

3D structure databases

ProteinModelPortaliP24399.
SMRiP24399. Positions 2-199.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiCOG5048.
GeneTreeiENSGT00750000117413.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiP24399.
OMAiMDEKPYK.
OrthoDBiEOG7KSX7Q.
PhylomeDBiP24399.
TreeFamiTF337055.

Family and domain databases

Gene3Di3.30.160.60. 7 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 7 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24399-1 [UniParc]FASTAAdd to Basket

« Hide

MAEKPYKCDK CGKGFTRSSS LLVHHSVHTG EKPFKCDRCG KGFSQSSKLH    50
IHKRVHTGEK PYACEECGMS FSQRSNLHIH QRVHTGERPY KCGECGKGFS 100
QSSNLHIHRC THTGEKPYQC YECGKGFSQS SDLRIHLRVH TGEKPYHCGK 150
CGQGFSQSSK LLIHQRVHTG EKPYECSKCG KGFSQSSNLH IHQRVHRKEL 200
H 201
Length:201
Mass (Da):22,818
Last modified:June 12, 2007 - v2
Checksum:iC7112D76DC7DC412
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti27 – 271V → L in AAA39729. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M32057 mRNA. Translation: AAA39729.1.
AK133328 mRNA. Translation: BAE21606.1.
BC003315 mRNA. Translation: AAH03315.1.
CCDSiCCDS20466.1.
PIRiI57505.
RefSeqiNP_001001792.1. NM_001001792.1.
NP_032642.2. NM_008616.2.
XP_006505991.1. XM_006505928.1.
XP_006505992.1. XM_006505929.1.
XP_006505993.1. XM_006505930.1.
XP_006505994.1. XM_006505931.1.
XP_006505995.1. XM_006505932.1.
XP_006505996.1. XM_006505933.1.
XP_006505997.1. XM_006505934.1.
XP_006505998.1. XM_006505935.1.
UniGeneiMm.249661.

Genome annotation databases

EnsembliENSMUST00000079405; ENSMUSP00000078374; ENSMUSG00000042097.
ENSMUST00000172088; ENSMUSP00000128270; ENSMUSG00000042097.
GeneIDi22685.
KEGGimmu:22685.
UCSCiuc009dlc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M32057 mRNA. Translation: AAA39729.1 .
AK133328 mRNA. Translation: BAE21606.1 .
BC003315 mRNA. Translation: AAH03315.1 .
CCDSi CCDS20466.1.
PIRi I57505.
RefSeqi NP_001001792.1. NM_001001792.1.
NP_032642.2. NM_008616.2.
XP_006505991.1. XM_006505928.1.
XP_006505992.1. XM_006505929.1.
XP_006505993.1. XM_006505930.1.
XP_006505994.1. XM_006505931.1.
XP_006505995.1. XM_006505932.1.
XP_006505996.1. XM_006505933.1.
XP_006505997.1. XM_006505934.1.
XP_006505998.1. XM_006505935.1.
UniGenei Mm.249661.

3D structure databases

ProteinModelPortali P24399.
SMRi P24399. Positions 2-199.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei P24399.

Proteomic databases

PRIDEi P24399.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000079405 ; ENSMUSP00000078374 ; ENSMUSG00000042097 .
ENSMUST00000172088 ; ENSMUSP00000128270 ; ENSMUSG00000042097 .
GeneIDi 22685.
KEGGi mmu:22685.
UCSCi uc009dlc.1. mouse.

Organism-specific databases

CTDi 22685.
MGIi MGI:1306812. Zfp239.

Phylogenomic databases

eggNOGi COG5048.
GeneTreei ENSGT00750000117413.
HOGENOMi HOG000234617.
HOVERGENi HBG018163.
InParanoidi P24399.
OMAi MDEKPYK.
OrthoDBi EOG7KSX7Q.
PhylomeDBi P24399.
TreeFami TF337055.

Miscellaneous databases

NextBioi 303115.
PROi P24399.
SOURCEi Search...

Gene expression databases

Bgeei P24399.
CleanExi MM_ZFP239.
Genevestigatori P24399.

Family and domain databases

Gene3Di 3.30.160.60. 7 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
Pfami PF00096. zf-C2H2. 1 hit.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 7 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A gene that encodes a protein consisting solely of zinc finger domains is preferentially expressed in transformed mouse cells."
    Ernoult-Lange M., Kress M., Hamer D.
    Mol. Cell. Biol. 10:418-421(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Testis.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: 129.
    Tissue: Mammary tumor.

Entry informationi

Entry nameiZN239_MOUSE
AccessioniPrimary (citable) accession number: P24399
Secondary accession number(s): Q99J71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: June 12, 2007
Last modified: July 9, 2014
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi