P24337 (HPSE_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Hydrophobic seed protein Short name=HPS Alternative name(s): Allergen=Gly m 1
Organism	Glycine max (Soybean) (Glycine hispida)
Taxonomic identifier	3847 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Phaseoleae › Glycine

Protein attributes

Sequence length	80 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Tissue specificity	Highly abundant in seeds.
Allergenic properties	Causes an allergic reaction in human.
Sequence similarities	Belongs to the plant LTP family. Highly divergent.

Ontologies

Keywords
Disease	Allergen
PTM	Disulfide bond
Technical term	3D-structure Direct protein sequencing
Gene Ontology (GO)
Biological process	lipid transport Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 80

80

Hydrophobic seed protein

PRO_0000153889

Amino acid modifications

Disulfide bond

8 ↔ 43

Ref.1

Disulfide bond

14 ↔ 28

Ref.1

Disulfide bond

29 ↔ 67

Ref.1

Disulfide bond

45 ↔ 77

Ref.1

Secondary structure

1

.

.

.

.

.

.

.

.

.

80

Helix Strand Turn

Details...

Helix

12 – 19

8

Helix

25 – 33

9

Helix

37 – 50

14

Helix

56 – 66

11

Sequences

	Sequence		Length	Mass (Da)
	P24337 [UniParc]. Last modified March 1, 1992. Version 1. Checksum: 6BF40B553E24D636	FASTA	80	8,359
	10 20 30 40 50 60 ALITRPSCPD LSICLNILGG SLGTVDDCCA LIGGLGDIEA IVCLCIQLRA LGILNLNRNL 70 80 QLILNSCGRS YPSNATCPRT

References

[1]	"Soybean hydrophobic protein. Isolation, partial characterization and the complete primary structure." Odani S., Koide T., Ono T., Seto Y., Tanaka T. Eur. J. Biochem. 162:485-491(1987) [PubMed: 3830151] [Abstract] Cited for: PROTEIN SEQUENCE, DISULFIDE BONDS. Tissue: Seed.
[2]	"Crystal structure of hydrophobic protein from soybean; a member of a new cysteine-rich family." Baud F., Pebay-Peyroula E., Cohen-Addad C., Odani S., Lehmann M.S. J. Mol. Biol. 231:877-887(1993) [PubMed: 8515457] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS).

Cross-references

Sequence databases

PIR

A29385.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1HYP	X-ray	1.80	A	1-80	[»]

ProteinModelPortal

P24337.

SMR

P24337. Positions 6-80.

ModBase

Search...

Protein family/group databases

Allergome

368. Gly m 1.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Gene expression databases

Genevestigator

P24337.

Family and domain databases

InterPro

IPR016140. Bifunc_inhib/LTP/seed_store.
IPR013770. Lipid_transfer_prot_hlx-dom.
IPR003612. LTP/seed_store/tryp_amyl_inhib.
[Graphical view]

Gene3D

G3DSA:1.10.110.10. LPT_helical. 1 hit.

SMART

SM00499. AAI. 1 hit.
[Graphical view]

SUPFAM

SSF47699. Bifunc_inhib/LTP/seed_store. 1 hit.

ProtoNet

Search...

Entry information

Entry name

HPSE_SOYBN

Accession

Primary (citable) accession number: P24337

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 1992
Last sequence update:	March 1, 1992
Last modified:	January 11, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program