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P24319

- RS8_THETH

UniProt

P24319 - RS8_THETH

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Protein

30S ribosomal protein S8

Gene
rpsH, rps8
Organism
Thermus thermophilus
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-KW
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S8
Gene namesi
Name:rpsH
Synonyms:rps8
OrganismiThermus thermophilus
Taxonomic identifieri274 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13813830S ribosomal protein S8UniRule annotationPRO_0000126512Add
BLAST

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S5 and S12 By similarity.

Protein-protein interaction databases

STRINGi262724.TTC1314.

Structurei

Secondary structure

1
138
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi5 – 1713
Turni18 – 203
Beta strandi22 – 276
Helixi30 – 4112
Beta strandi44 – 5310
Beta strandi56 – 638
Beta strandi65 – 684
Beta strandi70 – 723
Beta strandi75 – 795
Beta strandi83 – 853
Helixi97 – 993
Helixi103 – 1064
Beta strandi108 – 1147
Beta strandi117 – 1204
Helixi121 – 1277
Beta strandi131 – 1377

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1AN7X-ray2.90A/B3-138[»]
1TWTmodel-K1-138[»]
4BYBX-ray3.35H1-138[»]
ProteinModelPortaliP24319.
SMRiP24319. Positions 1-138.

Miscellaneous databases

EvolutionaryTraceiP24319.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

HAMAPiMF_01302_B. Ribosomal_S8_B.
InterProiIPR000630. Ribosomal_S8.
[Graphical view]
PANTHERiPTHR11758. PTHR11758. 1 hit.
PfamiPF00410. Ribosomal_S8. 1 hit.
[Graphical view]
SUPFAMiSSF56047. SSF56047. 1 hit.
PROSITEiPS00053. RIBOSOMAL_S8. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24319-1 [UniParc]FASTAAdd to Basket

« Hide

MLTDPIADML TRIRNATRVY KESTDVPASR FKEEILRILA REGFIKGYER    50
VDVDGKPYLR VYLKYGPRRQ GPDPRPEQVI HHIRRISKPG RRVYVGVKEI 100
PRVRRGLGIA ILSTSKGVLT DREARKLGVG GELICEVW 138
Length:138
Mass (Da):15,838
Last modified:May 10, 2005 - v2
Checksum:i49CC858AD1E4DB5A
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti64 – 641K → N in CAA62287. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X79551 Genomic DNA. Translation: CAA56094.1.
X90765 Genomic DNA. Translation: CAA62287.1.
PIRiS15441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X79551 Genomic DNA. Translation: CAA56094.1 .
X90765 Genomic DNA. Translation: CAA62287.1 .
PIRi S15441.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1AN7 X-ray 2.90 A/B 3-138 [» ]
1TWT model - K 1-138 [» ]
4BYB X-ray 3.35 H 1-138 [» ]
ProteinModelPortali P24319.
SMRi P24319. Positions 1-138.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 262724.TTC1314.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P24319.

Family and domain databases

HAMAPi MF_01302_B. Ribosomal_S8_B.
InterProi IPR000630. Ribosomal_S8.
[Graphical view ]
PANTHERi PTHR11758. PTHR11758. 1 hit.
Pfami PF00410. Ribosomal_S8. 1 hit.
[Graphical view ]
SUPFAMi SSF56047. SSF56047. 1 hit.
PROSITEi PS00053. RIBOSOMAL_S8. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The ribosomal protein S8 from Thermus thermophilus VK1. Sequencing of the gene, overexpression of the protein in Escherichia coli and interaction with rRNA."
    Vysotskaya V.S., Tischenko S., Garber M.B., Kern D., Ehresmann C., Ehresmann B.
    Eur. J. Biochem. 223:437-445(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: VK1.
  2. "Sequencing and analysis of the Thermus thermophilus ribosomal protein gene cluster equivalent to the spectinomycin operon."
    Vysotskaya V.S., Shcherbakov D.V., Garber M.B.
    Gene 193:23-30(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 38-138.
    Strain: VK1.
  3. "Crystal structure of ribosomal protein S8 from Thermus thermophilus reveals a high degree of structural conservation of a specific RNA binding site."
    Nevskaya N., Tishchenko S., Nikulin A., Al-Karadaghi S., Liljas A., Ehresmann B., Ehresmann C., Garber M.B., Nikonov S.
    J. Mol. Biol. 279:233-244(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS).
    Strain: VK1.

Entry informationi

Entry nameiRS8_THETH
AccessioniPrimary (citable) accession number: P24319
Secondary accession number(s): P74907
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: May 10, 2005
Last modified: February 19, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi