P24277 (RECR_BACSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Recombination protein recR

Gene names

Name:	recR
Synonyms:	recD, recM
Ordered Locus Names:	BSU00210

Organism

Bacillus subtilis

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in DNA repair. It seems to be involved in an recBC-independent recombinational process of DNA repair. It may act with recF and recO By similarity. HAMAP MF_00017
Sequence similarities	Belongs to the recR family. Contains 1 Toprim domain.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair
Domain	Zinc-finger
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA repair Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 198	198	Recombination protein recR HAMAP MF_00017		PRO_0000190283
Regions
	Domain	80 – 173	94	Toprim
	Zinc finger	57 – 72	16	C4-type Potential
Experimental info
	Sequence conflict	181 – 198	18	EYADE…GRREL → DMLMRSLFLKHLKEDVNCKE EKAIHGFSSQENIKKRV Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P24277 [UniParc]. Last modified October 1, 1994. Version 2. Checksum: 798359B7F22C68ED	FASTA	198	21,975
	10 20 30 40 50 60 MQYPEPISKL IDSFMKLPGI GPKTAVRLAF FVLGMKEDVV LDFAKALVNA KRNLTYCSVC 70 80 90 100 110 120 GHITDQDPCY ICEDTRRDKS VICVVQDPKD VIAMEKMKEY NGQYHVLHGA ISPMDGIGPE 130 140 150 160 170 180 DIKIPELLKR LQDDQVTEVI LATNPNIEGE ATAMYISRLL KPSGIKLSRI AHGLPVGGDL 190 EYADEVTLSK ALEGRREL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular cloning, genetic characterization and DNA sequence analysis of the recM region of Bacillus subtilis." Alonso J.C., Shirahige K., Ogasawara N. Nucleic Acids Res. 18:6771-6777(1990) [PubMed: 2124672] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168 / YB886 / BG214.
[2]	"Systematic sequencing of the 180 kilobase region of the Bacillus subtilis chromosome containing the replication origin." Ogasawara N., Nakai S., Yoshikawa H. DNA Res. 1:1-14(1994) [PubMed: 7584024] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[3]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X17014 Genomic DNA. Translation: CAA34879.1. D26185 Genomic DNA. Translation: BAA05257.1. AL009126 Genomic DNA. Translation: CAB11797.1.
PIR	B69691.
RefSeq	NP_387902.1. NC_000964.3.
3D structure databases
ProteinModelPortal	P24277.
SMR	P24277. Positions 1-198.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000003553; EBBACP00000003553; EBBACG00000003546.
GeneID	937197.
GenomeReviews	Gene locus BSU00210 in contig AL009126_GR.
KEGG	bsu:BSU00210.
NMPDR	fig|224308.1.peg.21.
PATRIC	18971503. VBIBacSub10457_0022.
Organism-specific databases
GenoList	BSU00210. [Micado]
Phylogenomic databases
GeneTree	EBGT00050000001138.
HOGENOM	HBG571744.
OMA	ILATDPN.
PhylomeDB	P24277.
ProtClustDB	PRK00076.
Enzyme and pathway databases
BioCyc	BSUB:BSU00210-MONOMER.
Family and domain databases
HAMAP	MF_00017. RecR. [Tree]
InterPro	IPR000093. DNA_Rcmb_RecR. IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif. IPR023627. Rcmb_RecR. IPR023628. Rcmb_RecR_C4-type_Zn. IPR015967. Rcmb_RecR_CS. IPR006171. Toprim_domain. [Graphical view]
KO	K06187.
Pfam	PF02132. RecR. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
SMART	SM00278. HhH1. 1 hit. SM00493. TOPRIM. 1 hit. [Graphical view]
SUPFAM	SSF111304. RecR. 1 hit.
TIGRFAMs	TIGR00615. RecR. 1 hit.
PROSITE	PS01300. RECR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECR_BACSU

Accession

Primary (citable) accession number: P24277

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 1992
Last sequence update:	October 1, 1994
Last modified:	January 25, 2012
This is version 95 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program