Reviewed, UniProtKB/Swiss-Prot P24272 (LUXE_VIBFI)

Names and origin

Protein names

Recommended name:
    Long-chain-fatty-acid--luciferin-component ligase
    EC=6.2.1.19
Alternative name(s):
    Acyl-protein synthetase

Gene names

Name:

luxE

Organism

Vibrio fischeri

Taxonomic identifier

668 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length	3 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Acyl-protein synthetase activates tetradecanoic acid. It is a component of the fatty acid reductase complex responsible for converting tetradecanoic acid to the aldehyde which serves as substrate in the luciferase-catalyzed reaction.
Catalytic activity	ATP + an acid + protein = AMP + diphosphate + an acyl-protein thioester.
Pathway	Lipid metabolism; bioluminescent fatty acid reduction.
Sequence similarities	Belongs to the luxE family.

Ontologies

Keywords
Biological process	Luminescence
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Biological process	bioluminescence Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW long-chain-fatty-acid-luciferin-component ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 3	›3	Long-chain-fatty-acid--luciferin-component ligase		PRO_0000208065
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	P24272-1 [UniParc]. Last modified March 1, 1992. Version 1. Checksum: 6AA3303000000000	FASTA	3	374
	IKD

References

[1]	"A new Vibrio fischeri lux gene precedes a bidirectional termination site for the lux operon." Swartzman E., Kapoor S., Graham A.F., Meighen E.A. J. Bacteriol. 172:6797-6802(1990) [PubMed: 2254256] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	M62812 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	6.2.1.19. 350.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

LUXE_VIBFI

Accession

Primary (citable) accession number: P24272

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 1992
Last sequence update:	March 1, 1992
Last modified:	June 16, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)