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Protein

Uncharacterized GTP-binding protein YjiA

Gene

yjiA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds GTP. May function as GTP-dependent regulator.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18GTPSequence analysis8
Nucleotide bindingi67 – 71GTPSequence analysis5
Nucleotide bindingi158 – 161GTPSequence analysis4

GO - Molecular functioni

  • GTPase activity Source: EcoCyc
  • GTP binding Source: UniProtKB-KW
  • identical protein binding Source: EcoCyc
  • transition metal ion binding Source: EcoCyc

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki
Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG10021-MONOMER.
ECOL316407:JW5790-MONOMER.
MetaCyc:EG10021-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized GTP-binding protein YjiA
Gene namesi
Name:yjiA
Ordered Locus Names:b4352, JW5790
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10021. yjiA.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001697851 – 318Uncharacterized GTP-binding protein YjiAAdd BLAST318

Proteomic databases

PaxDbiP24203.
PRIDEiP24203.

Interactioni

GO - Molecular functioni

  • identical protein binding Source: EcoCyc

Protein-protein interaction databases

BioGridi4262771. 12 interactors.
DIPiDIP-12630N.
IntActiP24203. 2 interactors.
STRINGi511145.b4352.

Structurei

Secondary structure

1318
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 16Combined sources13
Helixi18 – 26Combined sources9
Beta strandi33 – 36Combined sources4
Beta strandi45 – 50Combined sources6
Beta strandi56 – 60Combined sources5
Beta strandi65 – 67Combined sources3
Helixi73 – 85Combined sources13
Beta strandi92 – 99Combined sources8
Helixi104 – 113Combined sources10
Helixi115 – 120Combined sources6
Beta strandi121 – 131Combined sources11
Turni132 – 134Combined sources3
Helixi135 – 141Combined sources7
Helixi143 – 150Combined sources8
Beta strandi153 – 158Combined sources6
Turni160 – 162Combined sources3
Helixi167 – 176Combined sources10
Beta strandi178 – 180Combined sources3
Beta strandi182 – 184Combined sources3
Beta strandi187 – 189Combined sources3
Helixi192 – 195Combined sources4
Helixi218 – 221Combined sources4
Beta strandi223 – 233Combined sources11
Helixi237 – 250Combined sources14
Turni251 – 254Combined sources4
Beta strandi255 – 262Combined sources8
Beta strandi268 – 276Combined sources9
Beta strandi279 – 287Combined sources9
Beta strandi295 – 303Combined sources9
Helixi306 – 314Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NIJX-ray2.00A1-318[»]
4IXMX-ray2.57A/B1-318[»]
4IXNX-ray2.05A/B1-318[»]
ProteinModelPortaliP24203.
SMRiP24203.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP24203.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini224 – 317CobW C-terminalAdd BLAST94

Sequence similaritiesi

Contains 1 cobW C-terminal domain.Curated

Phylogenomic databases

eggNOGiENOG4105CKI. Bacteria.
COG0523. LUCA.
HOGENOMiHOG000182211.
InParanoidiP24203.
OMAiLIQSTHC.
PhylomeDBiP24203.

Family and domain databases

Gene3Di3.30.1220.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR011629. Cbl_biosynth_CobW-like_C.
IPR003495. CobW/HypB/UreG_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF02492. cobW. 1 hit.
PF07683. CobW_C. 1 hit.
[Graphical view]
SMARTiSM00833. CobW_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90002. SSF90002. 1 hit.

Sequencei

Sequence statusi: Complete.

P24203-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPIAVTLLT GFLGAGKTTL LRHILNEQHG YKIAVIENEF GEVSVDDQLI
60 70 80 90 100
GDRATQIKTL TNGCICCSRS NELEDALLDL LDNLDKGNIQ FDRLVIECTG
110 120 130 140 150
MADPGPIIQT FFSHEVLCQR YLLDGVIALV DAVHADEQMN QFTIAQSQVG
160 170 180 190 200
YADRILLTKT DVAGEAEKLH ERLARINARA PVYTVTHGDI DLGLLFNTNG
210 220 230 240 250
FMLEENVVST KPRFHFIADK QNDISSIVVE LDYPVDISEV SRVMENLLLE
260 270 280 290 300
SADKLLRYKG MLWIDGEPNR LLFQGVQRLY SADWDRPWGD EKPHSTMVFI
310
GIQLPEEEIR AAFAGLRK
Length:318
Mass (Da):35,660
Last modified:April 27, 2001 - v3
Checksum:i6D68463182031C41
GO

Sequence cautioni

The sequence AAA97249 differs from that shown. Reason: Frameshift at position 22.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97249.1. Frameshift.
U00096 Genomic DNA. Translation: AAC77308.2.
AP009048 Genomic DNA. Translation: BAE78342.1.
X54198 Genomic DNA. Translation: CAA38118.1.
PIRiS56578.
RefSeqiNP_418772.4. NC_000913.3.
WP_001312515.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77308; AAC77308; b4352.
BAE78342; BAE78342; BAE78342.
GeneIDi948882.
KEGGiecj:JW5790.
eco:b4352.
PATRICi32124310. VBIEscCol129921_4498.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA. Translation: AAA97249.1. Frameshift.
U00096 Genomic DNA. Translation: AAC77308.2.
AP009048 Genomic DNA. Translation: BAE78342.1.
X54198 Genomic DNA. Translation: CAA38118.1.
PIRiS56578.
RefSeqiNP_418772.4. NC_000913.3.
WP_001312515.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NIJX-ray2.00A1-318[»]
4IXMX-ray2.57A/B1-318[»]
4IXNX-ray2.05A/B1-318[»]
ProteinModelPortaliP24203.
SMRiP24203.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262771. 12 interactors.
DIPiDIP-12630N.
IntActiP24203. 2 interactors.
STRINGi511145.b4352.

Proteomic databases

PaxDbiP24203.
PRIDEiP24203.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77308; AAC77308; b4352.
BAE78342; BAE78342; BAE78342.
GeneIDi948882.
KEGGiecj:JW5790.
eco:b4352.
PATRICi32124310. VBIEscCol129921_4498.

Organism-specific databases

EchoBASEiEB0020.
EcoGeneiEG10021. yjiA.

Phylogenomic databases

eggNOGiENOG4105CKI. Bacteria.
COG0523. LUCA.
HOGENOMiHOG000182211.
InParanoidiP24203.
OMAiLIQSTHC.
PhylomeDBiP24203.

Enzyme and pathway databases

BioCyciEcoCyc:EG10021-MONOMER.
ECOL316407:JW5790-MONOMER.
MetaCyc:EG10021-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP24203.
PROiP24203.

Family and domain databases

Gene3Di3.30.1220.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR011629. Cbl_biosynth_CobW-like_C.
IPR003495. CobW/HypB/UreG_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF02492. cobW. 1 hit.
PF07683. CobW_C. 1 hit.
[Graphical view]
SMARTiSM00833. CobW_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90002. SSF90002. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYJIA_ECOLI
AccessioniPrimary (citable) accession number: P24203
Secondary accession number(s): Q2M5W4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: April 27, 2001
Last modified: November 2, 2016
This is version 124 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.