Uncharacterized GTP-binding protein YjiA - Escherichia coli (strain K12)

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P24203 (YJIA_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 101. History...

Clusters with 100%, 90%, 50% identity |

Documents (3) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Uncharacterized GTP-binding protein YjiA

Gene names

Name:	yjiA
Ordered Locus Names:	b4352, JW5790

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length	318 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function

Binds GTP. May function as GTP-dependent regulator. Ref.5

Sequence similarities

Belongs to the CobW family.

Contains 1 cobW C-terminal domain.

Sequence caution

The sequence AAA97249.1 differs from that shown. Reason: Frameshift at position 22.

Ontologies

Keywords
Ligand	GTP-binding Nucleotide-binding
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to DNA damage stimulus Inferred from expression pattern PubMed 11967071. Source: EcoliWiki
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 318

318

Uncharacterized GTP-binding protein YjiA

PRO_0000169785

Regions

Domain

224 – 317

CobW C-terminal

Nucleotide binding

11 – 18

GTP Potential

Nucleotide binding

67 – 71

GTP Potential

Nucleotide binding

158 – 161

GTP Potential

Secondary structure

318

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

P24203 [UniParc].

Last modified April 27, 2001. Version 3.
Checksum: 6D68463182031C41
Show »

FASTA

318

35,660

        10         20         30         40         50         60 
MNPIAVTLLT GFLGAGKTTL LRHILNEQHG YKIAVIENEF GEVSVDDQLI GDRATQIKTL 

        70         80         90        100        110        120 
TNGCICCSRS NELEDALLDL LDNLDKGNIQ FDRLVIECTG MADPGPIIQT FFSHEVLCQR 

       130        140        150        160        170        180 
YLLDGVIALV DAVHADEQMN QFTIAQSQVG YADRILLTKT DVAGEAEKLH ERLARINARA 

       190        200        210        220        230        240 
PVYTVTHGDI DLGLLFNTNG FMLEENVVST KPRFHFIADK QNDISSIVVE LDYPVDISEV 

       250        260        270        280        290        300 
SRVMENLLLE SADKLLRYKG MLWIDGEPNR LLFQGVQRLY SADWDRPWGD EKPHSTMVFI 

       310 
GIQLPEEEIR AAFAGLRK

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes." Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R. Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Characterization and expression of the Escherichia coli Mrr restriction system." Waite-Rees P.A., Keating C.J., Moran L.S., Slatko B.E., Hornstra L.J., Benner J.S. J. Bacteriol. 173:5207-5219(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 39-318. Strain: K12.
[5]	"Crystal structure of the Escherichia coli YjiA protein suggests a GTP-dependent regulatory function." Khil P.P., Obmolova G., Teplyakov A., Howard A.J., Gilliland G.L., Camerini-Otero R.D. Proteins 54:371-374(2004) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS), FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U14003 Genomic DNA. Translation: AAA97249.1. Frameshift.
U00096 Genomic DNA. Translation: AAC77308.2.
AP009048 Genomic DNA. Translation: BAE78342.1.
X54198 Genomic DNA. Translation: CAA38118.1.

PIR

S56578.

RefSeq

NP_418772.4. NC_000913.2.
YP_492483.1. NC_007779.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1NIJ	X-ray	2.00	A	1-318	[»]
4IXM	X-ray	2.57	A/B	1-318	[»]
4IXN	X-ray	2.05	A/B	1-318	[»]

ProteinModelPortal

P24203.

SMR

P24203. Positions 2-318.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-12630N.

IntAct

P24203. 1 interaction.

STRING

511145.b4352.

Proteomic databases

PaxDb

P24203.

PRIDE

P24203.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAC77308; AAC77308; b4352.
BAE78342; BAE78342; BAE78342.

GeneID

12933777.
948882.

KEGG

ecj:Y75_p4237.
eco:b4352.

PATRIC

32124310. VBIEscCol129921_4498.

Organism-specific databases

EchoBASE

EB0020.

EcoGene

EG10021. yjiA.

Phylogenomic databases

eggNOG

COG0523.

HOGENOM

HOG000182211.

OMA

RINRRAP.

ProtClustDB

PRK11537.

Enzyme and pathway databases

BioCyc

EcoCyc:EG10021-MONOMER.
ECOL316407:JW5790-MONOMER.

Gene expression databases

Genevestigator

P24203.

Family and domain databases

Gene3D

3.30.1220.10. 1 hit.

InterPro

IPR011629. Cbl_biosynth_CobW-like_C.
IPR003495. CobW/HypB/UreG_dom.
[Graphical view]

Pfam

PF02492. cobW. 1 hit.
PF07683. CobW_C. 1 hit.
[Graphical view]

SMART

SM00833. CobW_C. 1 hit.
[Graphical view]

SUPFAM

SSF90002. Cbl_biosynth_CobW-like_C. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

P24203.

Entry information

Entry name

YJIA_ECOLI

Accession

Primary (citable) accession number: P24203
Secondary accession number(s): Q2M5W4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 1992
Last sequence update:	April 27, 2001
Last modified:	May 1, 2013
This is version 101 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Secondary structure

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

Other

Entry information

Relevant documents