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P24203 (YJIA_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized GTP-binding protein YjiA
Gene names
Name:yjiA
Ordered Locus Names:b4352, JW5790
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Binds GTP. May function as GTP-dependent regulator. Ref.5

Sequence similarities

Belongs to the CobW family.

Contains 1 cobW C-terminal domain.

Sequence caution

The sequence AAA97249.1 differs from that shown. Reason: Frameshift at position 22.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Uncharacterized GTP-binding protein YjiA
PRO_0000169785

Regions

Domain224 – 31794CobW C-terminal
Nucleotide binding11 – 188GTP Potential
Nucleotide binding67 – 715GTP Potential
Nucleotide binding158 – 1614GTP Potential

Secondary structure

........................................................ 318
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P24203 [UniParc].

Last modified April 27, 2001. Version 3.
Checksum: 6D68463182031C41

FASTA31835,660
        10         20         30         40         50         60 
MNPIAVTLLT GFLGAGKTTL LRHILNEQHG YKIAVIENEF GEVSVDDQLI GDRATQIKTL 

        70         80         90        100        110        120 
TNGCICCSRS NELEDALLDL LDNLDKGNIQ FDRLVIECTG MADPGPIIQT FFSHEVLCQR 

       130        140        150        160        170        180 
YLLDGVIALV DAVHADEQMN QFTIAQSQVG YADRILLTKT DVAGEAEKLH ERLARINARA 

       190        200        210        220        230        240 
PVYTVTHGDI DLGLLFNTNG FMLEENVVST KPRFHFIADK QNDISSIVVE LDYPVDISEV 

       250        260        270        280        290        300 
SRVMENLLLE SADKLLRYKG MLWIDGEPNR LLFQGVQRLY SADWDRPWGD EKPHSTMVFI 

       310 
GIQLPEEEIR AAFAGLRK 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
Nucleic Acids Res. 23:2105-2119(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Characterization and expression of the Escherichia coli Mrr restriction system."
Waite-Rees P.A., Keating C.J., Moran L.S., Slatko B.E., Hornstra L.J., Benner J.S.
J. Bacteriol. 173:5207-5219(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 39-318.
Strain: K12.
[5]"Crystal structure of the Escherichia coli YjiA protein suggests a GTP-dependent regulatory function."
Khil P.P., Obmolova G., Teplyakov A., Howard A.J., Gilliland G.L., Camerini-Otero R.D.
Proteins 54:371-374(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS), FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U14003 Genomic DNA. Translation: AAA97249.1. Frameshift.
U00096 Genomic DNA. Translation: AAC77308.2.
AP009048 Genomic DNA. Translation: BAE78342.1.
X54198 Genomic DNA. Translation: CAA38118.1.
PIRS56578.
RefSeqNP_418772.4. NC_000913.3.
YP_492483.1. NC_007779.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1NIJX-ray2.00A1-318[»]
4IXMX-ray2.57A/B1-318[»]
4IXNX-ray2.05A/B1-318[»]
ProteinModelPortalP24203.
SMRP24203. Positions 2-318.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-12630N.
IntActP24203. 2 interactions.
STRING511145.b4352.

Proteomic databases

PaxDbP24203.
PRIDEP24203.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC77308; AAC77308; b4352.
BAE78342; BAE78342; BAE78342.
GeneID12933777.
948882.
KEGGecj:Y75_p4237.
eco:b4352.
PATRIC32124310. VBIEscCol129921_4498.

Organism-specific databases

EchoBASEEB0020.
EcoGeneEG10021. yjiA.

Phylogenomic databases

eggNOGCOG0523.
HOGENOMHOG000182211.
OMALDLRGFN.
OrthoDBEOG63RGPZ.
PhylomeDBP24203.
ProtClustDBPRK11537.

Enzyme and pathway databases

BioCycEcoCyc:EG10021-MONOMER.
ECOL316407:JW5790-MONOMER.
MetaCyc:EG10021-MONOMER.

Gene expression databases

GenevestigatorP24203.

Family and domain databases

Gene3D3.30.1220.10. 1 hit.
3.40.50.300. 1 hit.
InterProIPR011629. Cbl_biosynth_CobW-like_C.
IPR003495. CobW/HypB/UreG_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF02492. cobW. 1 hit.
PF07683. CobW_C. 1 hit.
[Graphical view]
SMARTSM00833. CobW_C. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
SSF90002. SSF90002. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP24203.
PROP24203.

Entry information

Entry nameYJIA_ECOLI
AccessionPrimary (citable) accession number: P24203
Secondary accession number(s): Q2M5W4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: April 27, 2001
Last modified: April 16, 2014
This is version 108 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene