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Protein

Mrr restriction system protein

Gene

mrr

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the acceptance of foreign DNA which is modified. Restricts both adenine- and cytosine-methylated DNA.

GO - Molecular functioni

  • DNA binding Source: InterPro
  • restriction endodeoxyribonuclease activity Source: EcoCyc
  • Type IV site-specific deoxyribonuclease activity Source: EcoCyc

GO - Biological processi

  • DNA restriction-modification system Source: UniProtKB-KW
  • response to hydrostatic pressure Source: EcoCyc

Keywordsi

Biological processRestriction system

Enzyme and pathway databases

BioCyciEcoCyc:EG10612-MONOMER

Protein family/group databases

REBASEi2906 EcoKMrr

Names & Taxonomyi

Protein namesi
Recommended name:
Mrr restriction system protein
Alternative name(s):
EcoKMrr
Gene namesi
Name:mrr
Ordered Locus Names:b4351, JW4314
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10612 mrr

Subcellular locationi

GO - Cellular componenti

  • bacterial nucleoid Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000773821 – 304Mrr restriction system proteinAdd BLAST304

Proteomic databases

PaxDbiP24202
PRIDEiP24202

Interactioni

Protein-protein interaction databases

BioGridi4262770, 58 interactors
DIPiDIP-10259N
IntActiP24202, 1 interactor
STRINGi316407.85677091

Structurei

3D structure databases

ProteinModelPortaliP24202
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4106H3A Bacteria
COG1715 LUCA
HOGENOMiHOG000015253
InParanoidiP24202
KOiK07448
OMAiVIYIQAK
PhylomeDBiP24202

Family and domain databases

InterProiView protein in InterPro
IPR025745 Mrr-like_N_dom
IPR011335 Restrct_endonuc-II-like
IPR007560 Restrct_endonuc_IV_Mrr
PfamiView protein in Pfam
PF04471 Mrr_cat, 1 hit
PF14338 Mrr_N, 1 hit
SUPFAMiSSF52980 SSF52980, 1 hit

Sequencei

Sequence statusi: Complete.

P24202-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVPTYDKFI EPVLRYLATK PEGAAARDVH EAAADALGLD DSQRAKVITS
60 70 80 90 100
GQLVYKNRAG WAHDRLKRAG LSQSLSRGKW CLTPAGFDWV ASHPQPMTEQ
110 120 130 140 150
ETNHLAFAFV NVKLKSRPDA VDLDPKADSP DHEELAKSSP DDRLDQALKE
160 170 180 190 200
LRDAVADEVL ENLLQVSPSR FEVIVLDVLH RLGYGGHRDD LQRVGGTGDG
210 220 230 240 250
GIDGVISLDK LGLEKVYVQA KRWQNTVGRP ELQAFYGALA GQKAKRGVFI
260 270 280 290 300
TTSGFTSQAR DFAQSVEGMV LVDGERLVHL MIENEVGVSS RLLKVPKLDM

DYFE
Length:304
Mass (Da):33,520
Last modified:March 1, 1992 - v1
Checksum:i6DE16E229E9EC9AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54198 Genomic DNA Translation: CAA38117.1
U14003 Genomic DNA Translation: AAA97248.1
U00096 Genomic DNA Translation: AAC77307.1
AP009048 Genomic DNA Translation: BAE78341.1
PIRiA40368
RefSeqiNP_418771.1, NC_000913.3
WP_000217931.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77307; AAC77307; b4351
BAE78341; BAE78341; BAE78341
GeneIDi948898
KEGGiecj:JW4314
eco:b4351
PATRICifig|1411691.4.peg.2335

Similar proteinsi

Entry informationi

Entry nameiMRR_ECOLI
AccessioniPrimary (citable) accession number: P24202
Secondary accession number(s): Q2M5W5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: March 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

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