Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Mrr restriction system protein

Gene

mrr

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the acceptance of foreign DNA which is modified. Restricts both adenine- and cytosine-methylated DNA.

GO - Molecular functioni

  • DNA binding Source: InterPro
  • restriction endodeoxyribonuclease activity Source: EcoCyc
  • Type IV site-specific deoxyribonuclease activity Source: EcoCyc

GO - Biological processi

  • DNA restriction-modification system Source: UniProtKB-KW
  • response to hydrostatic pressure Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Restriction system

Enzyme and pathway databases

BioCyciEcoCyc:EG10612-MONOMER.
ECOL316407:JW4314-MONOMER.

Protein family/group databases

REBASEi2906. EcoKMrr.

Names & Taxonomyi

Protein namesi
Recommended name:
Mrr restriction system protein
Alternative name(s):
EcoKMrr
Gene namesi
Name:mrr
Ordered Locus Names:b4351, JW4314
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10612. mrr.

Subcellular locationi

GO - Cellular componenti

  • bacterial nucleoid Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304Mrr restriction system proteinPRO_0000077382Add
BLAST

Proteomic databases

PaxDbiP24202.
PRIDEiP24202.

Interactioni

Protein-protein interaction databases

BioGridi4262770. 56 interactions.
DIPiDIP-10259N.
IntActiP24202. 1 interaction.
MINTiMINT-1267575.
STRINGi511145.b4351.

Structurei

3D structure databases

ProteinModelPortaliP24202.
SMRiP24202. Positions 167-284.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4106H3A. Bacteria.
COG1715. LUCA.
HOGENOMiHOG000015253.
InParanoidiP24202.
KOiK07448.
OMAiVIYIQAK.
PhylomeDBiP24202.

Family and domain databases

Gene3Di3.40.1350.10. 1 hit.
InterProiIPR025745. Mrr-like_N_dom.
IPR011335. Restrct_endonuc-II-like.
IPR007560. Restrct_endonuc_IV_Mrr.
IPR011856. tRNA_endonuc-like_dom.
[Graphical view]
PfamiPF04471. Mrr_cat. 1 hit.
PF14338. Mrr_N. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.

Sequencei

Sequence statusi: Complete.

P24202-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVPTYDKFI EPVLRYLATK PEGAAARDVH EAAADALGLD DSQRAKVITS
60 70 80 90 100
GQLVYKNRAG WAHDRLKRAG LSQSLSRGKW CLTPAGFDWV ASHPQPMTEQ
110 120 130 140 150
ETNHLAFAFV NVKLKSRPDA VDLDPKADSP DHEELAKSSP DDRLDQALKE
160 170 180 190 200
LRDAVADEVL ENLLQVSPSR FEVIVLDVLH RLGYGGHRDD LQRVGGTGDG
210 220 230 240 250
GIDGVISLDK LGLEKVYVQA KRWQNTVGRP ELQAFYGALA GQKAKRGVFI
260 270 280 290 300
TTSGFTSQAR DFAQSVEGMV LVDGERLVHL MIENEVGVSS RLLKVPKLDM

DYFE
Length:304
Mass (Da):33,520
Last modified:March 1, 1992 - v1
Checksum:i6DE16E229E9EC9AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54198 Genomic DNA. Translation: CAA38117.1.
U14003 Genomic DNA. Translation: AAA97248.1.
U00096 Genomic DNA. Translation: AAC77307.1.
AP009048 Genomic DNA. Translation: BAE78341.1.
PIRiA40368.
RefSeqiNP_418771.1. NC_000913.3.
WP_000217931.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77307; AAC77307; b4351.
BAE78341; BAE78341; BAE78341.
GeneIDi948898.
KEGGiecj:JW4314.
eco:b4351.
PATRICi32124308. VBIEscCol129921_4497.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54198 Genomic DNA. Translation: CAA38117.1.
U14003 Genomic DNA. Translation: AAA97248.1.
U00096 Genomic DNA. Translation: AAC77307.1.
AP009048 Genomic DNA. Translation: BAE78341.1.
PIRiA40368.
RefSeqiNP_418771.1. NC_000913.3.
WP_000217931.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP24202.
SMRiP24202. Positions 167-284.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262770. 56 interactions.
DIPiDIP-10259N.
IntActiP24202. 1 interaction.
MINTiMINT-1267575.
STRINGi511145.b4351.

Protein family/group databases

REBASEi2906. EcoKMrr.

Proteomic databases

PaxDbiP24202.
PRIDEiP24202.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77307; AAC77307; b4351.
BAE78341; BAE78341; BAE78341.
GeneIDi948898.
KEGGiecj:JW4314.
eco:b4351.
PATRICi32124308. VBIEscCol129921_4497.

Organism-specific databases

EchoBASEiEB0607.
EcoGeneiEG10612. mrr.

Phylogenomic databases

eggNOGiENOG4106H3A. Bacteria.
COG1715. LUCA.
HOGENOMiHOG000015253.
InParanoidiP24202.
KOiK07448.
OMAiVIYIQAK.
PhylomeDBiP24202.

Enzyme and pathway databases

BioCyciEcoCyc:EG10612-MONOMER.
ECOL316407:JW4314-MONOMER.

Miscellaneous databases

PROiP24202.

Family and domain databases

Gene3Di3.40.1350.10. 1 hit.
InterProiIPR025745. Mrr-like_N_dom.
IPR011335. Restrct_endonuc-II-like.
IPR007560. Restrct_endonuc_IV_Mrr.
IPR011856. tRNA_endonuc-like_dom.
[Graphical view]
PfamiPF04471. Mrr_cat. 1 hit.
PF14338. Mrr_N. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMRR_ECOLI
AccessioniPrimary (citable) accession number: P24202
Secondary accession number(s): Q2M5W5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: September 7, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.