Reviewed, UniProtKB/Swiss-Prot P24168 (CATA_LISSE)

Names and origin

Protein names

Recommended name:
    Catalase
    EC=1.11.1.6

Gene names

Name:

kat

Organism

Listeria seeligeri

Taxonomic identifier

1640 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	488 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H2O2 = O2 + 2 H2O.
Cofactor	Heme group.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Cytoplasm
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 488	488	Catalase		PRO_0000085017
Sites
	Active site	55	1	By similarity
	Active site	128	1	By similarity
	Metal binding	338	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P24168-1 [UniParc]. Last modified March 1, 1992. Version 1. Checksum: F0A3251469681EBB	FASTA	488	55,869
	10 20 30 40 50 60 MTDRRNLTTN QGVPIGDNQN SMTAGLKGPT LLEDYVLIEK LAHFDRERVP ERVVHARGAG 70 80 90 100 110 120 AHGKFVTKKS MKKYTKAQFL QEEGTETEVF ARFSTVIHGQ HSPETLRDPR GFSVKFYTEE 130 140 150 160 170 180 GNYDFVGNNL PVFFIRDAIK FPDVIHSLKP DPRTNIQDGN RYWDFFSLTP EATTMITYLF 190 200 210 220 230 240 SDEGTPASYR EIRGSSVHAF KWINEEGKTV YVKLRWVPKA GIVNLSTDQA AQIQAKEFNH 250 260 270 280 290 300 ASRDLYEAIE NGDYPEWDLY VQVLDPKDLD NYDFNPLDAT KDWFEDVFPY EHVGTMTLNR 310 320 330 340 350 360 NPDNIFAETE SVGFNPGVLV PGMLPSEDRV LQGRLFSYSD TQRHRVGPNY LQLPINSPKT 370 380 390 400 410 420 PVDNNQRDGQ MPFKQQTSSI NYEPNSYDTE PKENPAYIEP EQEIRGDISG RLVAEKPNNF 430 440 450 460 470 480 GHAKEVWKRY SDAERAALVK NIVDDWEGVR EDIKIRNLRN FYQVEPEFAE RVAAGTGINL AEHVIDLK

References

[1]

"Cloning, characterization, and expression in Escherichia coli of a gene encoding Listeria seeligeri catalase, a bacterial enzyme highly homologous to mammalian catalases." Haas A., Brehm K., Kreft J., Goebel W. J. Bacteriol. 173:5159-5167(1991) [PubMed: 1860824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	M75944 Genomic DNA. Translation: AAB53655.1.
PIR	A40367.
3D structure databases
HSSP	HSSP built from PDB template 1M7S based on UniProtKB P46206.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.11.1.6. 260965.
Family and domain databases
InterPro	IPR002226. Catalase. IPR010582. Catalase-rel_immune_responsive. IPR011614. Catalase_N. IPR018028. Catalase_rel_subgroup. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_LISSE

Accession

Primary (citable) accession number: P24168

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 1992
Last sequence update:	March 1, 1992
Last modified:	June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)