Skip Header

Contribute Send feedback
Read comments (?) or add your own

P24157 (ACCO4_SOLLC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1-aminocyclopropane-1-carboxylate oxidase 4
Short name=ACC oxidase 4
EC=1.14.17.4
Alternative name(s):
Ethylene-forming enzyme
Short name=EFE
Protein pHTOM5
Gene names
Name:ACO4
Synonyms:ACO3
OrganismSolanum lycopersicum (Tomato) (Lycopersicon esculentum) [Reference proteome]
Taxonomic identifier4081 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

1-aminocyclopropane-1-carboxylate + ascorbate + O2 = ethylene + cyanide + dehydroascorbate + CO2 + 2 H2O.

Cofactor

Iron.

Pathway

Alkene biosynthesis; ethylene biosynthesis via S-adenosyl-L-methionine; ethylene from S-adenosyl-L-methionine: step 2/2.

Tissue specificity

Expressed in all of the floral organs examined apart from the sepals.

Sequence similarities

Belongs to the iron/ascorbate-dependent oxidoreductase family.

Contains 1 Fe2OG dioxygenase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3163161-aminocyclopropane-1-carboxylate oxidase 4
PRO_0000067263

Regions

Domain153 – 253101Fe2OG dioxygenase

Sites

Metal binding1771Iron By similarity
Metal binding1791Iron By similarity
Metal binding2341Iron By similarity

Sequences

Sequence LengthMass (Da)Tools
P24157 [UniParc].

Last modified March 1, 1992. Version 1.
Checksum: DE1C708950339AE7

FASTA31635,974
        10         20         30         40         50         60 
MENFPIINLE NLNGDERAKT MEMIKDACEN WGFFELVNHG IPHEVMDTVE KLTKGHYKKC 

        70         80         90        100        110        120 
MEQRFKELVA SKGLEAVQAE VTDLDWESTF FLRHLPTSNI SQVPDLDEEY REVMRDFAKR 

       130        140        150        160        170        180 
LEKLAEELLD LLCENLGLEK GYLKNAFYGS KGPNFGTKVS NYPPCPKPDL IKGLRAHTDA 

       190        200        210        220        230        240 
GGIILLFQDD KVSGLQLLKD EQWIDVPPMR HSIVVNLGDQ LEVITNGKYK SVMHRVIAQT 

       250        260        270        280        290        300 
DGTRMSLASF YNPGNDAVIY PAPSLIEESK QVYPKFVFDD YMKLYAGLKF QPKEPRFEAM 

       310 
KAMEANVELV DQIASA

« Hide

References

[1]"Analysis and cloning of the ethylene-forming enzyme from tomato by functional expression of its mRNA in Xenopus laevis oocytes."
Spanu P., Reinhardt D., Boller T.
EMBO J. 10:2007-2013(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Differential expression of the 1-aminocyclopropane-1-carboxylate oxidase gene family of tomato."
Barry C.S., Blume B., Bouzayen M., Cooper W., Hamilton A.J., Grierson D.
Plant J. 9:525-535(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Ailsa Craig.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X58885 mRNA. Translation: CAA41689.1.
Z54199 Genomic DNA. Translation: CAA90904.1.
PIRS16327.
RefSeqNP_001233928.1. NM_001246999.1.
UniGeneLes.132.

3D structure databases

ProteinModelPortalP24157.
SMRP24157. Positions 2-303.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsSolyc07g049550.2.1; Solyc07g049550.2.1; Solyc07g049550.2.
GeneID544285.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-15536.
BRENDA1.14.17.4. 3101.
UniPathwayUPA00384; UER00563.

Family and domain databases

InterProIPR026992. DIOX_N.
IPR005123. Oxoglu/Fe-dep_dioxygenase.
[Graphical view]
PfamPF03171. 2OG-FeII_Oxy. 1 hit.
PF14226. DIOX_N. 1 hit.
[Graphical view]
PROSITEPS51471. FE2OG_OXY. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACCO4_SOLLC
AccessionPrimary (citable) accession number: P24157
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: April 3, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents