P24128 (FUSC_BURCE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fusaric acid resistance protein FusC

Gene names

Name:

fusC

Organism

Burkholderia cepacia (Pseudomonas cepacia)

Taxonomic identifier

292 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the resistance (detoxification) of the fungal toxin fusaric acid.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family. [View classification]

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Gene Ontology (GO)
Biological_process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 346	346	Fusaric acid resistance protein FusC		PRO_0000210088
Regions
	Transmembrane	10 – 30	21	Helical; Potential
	Transmembrane	248 – 268	21	Helical; Potential
	Transmembrane	291 – 311	21	Helical; Potential
	Transmembrane	315 – 335	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P24128 [UniParc]. Last modified March 1, 1992. Version 1. Checksum: 6BCC53A01E24CE9E	FASTA	346	37,870
	10 20 30 40 50 60 MSAMTRVSEV IIGIVSAGVV SALVFPRYTG EQMRTTVRKR FGSFVDYVAS ALSGQLDRAH 70 80 90 100 110 120 IETIHTRFAY VVGFEAARSM AVFEDPDTRM RSGRLARLNS EFMSASSRFH ALHQLMNRLH 130 140 150 160 170 180 AAGAQAAIDA IEPYFREIAP LLTRNGEPVR TSIDAAHSAE QLLAWRDALP RRIRATRAEL 190 200 210 220 230 240 ETQPDFPLLD FDTAAELLYR FITDLQEYAA TYASLATATH ERERWIERYE PRTNKTAATI 250 260 270 280 290 300 AGIRTATVIL ALGWFWIETA WPSGVMLVLN AAATCALASS APRPTAMAAQ MGMGTALAVC 310 320 330 340 TGFLLTFGIY PRIDGFVLLC AALAPLLAIG IYMSLKPKLA GYGGAI

References

[1]

"Molecular cloning and characterization of the fusaric acid-resistance gene from Pseudomonas cepacia." Utsumi R., Yagi T., Katayama S., Katsuragi K., Tachibana K., Toyoda H., Ouchi S., Obata K., Shibano Y., Noda M. Agric. Biol. Chem. 55:1913-1918(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: UK1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	S77489 Genomic DNA. Translation: AAC60390.1. D12503 Genomic DNA. Translation: BAA02066.1.
PIR	JS0511.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR006726. PHBA_efflux_AaeB/fusaric-R. [Graphical view]
Pfam	PF04632. FUSC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FUSC_BURCE

Accession

Primary (citable) accession number: P24128

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 1992
Last sequence update:	March 1, 1992
Last modified:	April 3, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program