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Reviewed, UniProtKB/Swiss-Prot P24095 (LOXX_SOYBN)

Last modified November 25, 2008. Version 72. Feed History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Seed lipoxygenase
    EC=1.13.11.12
Gene names
Name: LOX1.4
Synonyms: SC514
OrganismGlycine max (Soybean)
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidseurosids IFabalesFabaceaePapilionoideaePhaseoleaeGlycine

Protein attributes

Sequence length864 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. It catalyzes the hydroperoxidation of lipids, containing a cis,cis-1,4-pentadiene structure.

Catalytic activity

Linoleate + O(2) = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.

Cofactor

Binds 1 iron ion per subunit. Iron is tightly bound.

Pathway

Lipid metabolism; oxylipin biosynthesis.

Subunit structure

Monomer.

Subcellular location

Cytoplasm.

Tissue specificity

Germinated cotyledons.

Induction

By jasmonate.

Miscellaneous

Soybean contains at least 4 distinct isoenzymes, L-1, L-2, L-3a and L-3b in dry seeds, and at least two distinct isozymes in the hypocotyl/radicle region of the seedling stem.

Sequence similarities

Belongs to the lipoxygenase family.

Contains 1 lipoxygenase domain.

Contains 1 PLAT domain.

Ontologies

Keywords

   Biological processFatty acid biosynthesis
Lipid synthesis
Oxylipin biosynthesis
   Cellular componentCytoplasm
   LigandIron
Metal-binding
   Molecular functionDioxygenase
Oxidoreductase
   Technical term3D-structure

Gene Ontology (GO)

   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

oxylipin biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionelectron carrier activity

Inferred from electronic annotation. Source: InterPro

iron ion binding

Inferred from electronic annotation. Source: InterPro

lipoxygenase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 864864Seed lipoxygenase
PRO_0000220721

Regions

Domain44 – 171128PLAT
Domain174 – 864691Lipoxygenase

Sites

Metal binding5251Iron; catalytic
Metal binding5301Iron; catalytic
Metal binding7161Iron; catalytic
Metal binding7201Iron; catalytic
Metal binding8641Iron; via carboxylate; catalytic

Experimental info

Sequence conflict2331S → C in AAA03728. Ref.2
Sequence conflict2401R → L in AAA03728. Ref.2
Sequence conflict6041D → H in AAA03728. Ref.2
Sequence conflict6951M → K in AAA03728. Ref.2

Secondary structure

.................................................................................................................................................. 864
Helix Strand Turn

Details...