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Protein

Protein TraN

Gene

traN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for F plasmid conjugative transfer. May interact with the recipient cell surface to stabilize mating pairs initiated by F-pili. May interact with TraG.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Conjugation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TraN
Gene namesi
Name:traN
Ordered Locus Names:ECOK12F089
Encoded oniPlasmid F0 Publication
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence AnalysisAdd
BLAST
Chaini19 – 602584Protein TraNPRO_0000024508Add
BLAST

Proteomic databases

PRIDEiP24082.

Structurei

3D structure databases

ProteinModelPortaliP24082.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

KOiK12058.
OMAiESCPFSK.

Family and domain databases

InterProiIPR014121. TraN_Ftype.
[Graphical view]
PfamiPF06986. TraN. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02750. TraN_Ftype. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P24082-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRILPLILA LVAGMAQADS NSDYRAGSDF AHQIKGQGSS SIQGFKPQES
60 70 80 90 100
IPGYNANPDE TKYYGGVTAG GDGGLKNDGT TEWATGETGK TITESFMNKP
110 120 130 140 150
KDILSPDAPF IQTGRDVVNR ADSIVGNTGQ QCSAQEISRS EYTNYTCERD
160 170 180 190 200
LQVEQYCTRT ARMELQGSTT WETRTLEYEM SQLPAREVNG QYVVSITSPV
210 220 230 240 250
TGEIVDAHYS WSRTYLQKSV PMTITVLGTP LSWNAKYSAD ASFTPVQKTL
260 270 280 290 300
TAGVAFTSSH PVRVGNTKFK RHTAMKLRLV VRVKKASYTP YVVWSESCPF
310 320 330 340 350
SKELGKLTKT ECTEAGGNRT LVKDGQSYSM YQSCWAYRDT YVTQSADKGT
360 370 380 390 400
CQTYTDNPAC TLVSHQCAFY SEEGACLHEY ATYSCESKTS GKVMVCGGDV
410 420 430 440 450
FCLDGECDKA QSGKSNDFAE AVSQLAALAA AGKDVAALNG VDVRAFTGQA
460 470 480 490 500
KFCKKAAAGY SNCCKDSGWG QDIGLAKCSS DEKALAKAKS NKLTVSVGEF
510 520 530 540 550
CSKKVLGVCL EKKRSYCQFD SKLAQIVQQQ GRNGQLRISF GSAKHPDCRG
560 570 580 590 600
ITVDELQKIQ FNRLDFTNFY EDLMNNQKIP DSGVLTQKVK EQIADQLKQA

GQ
Length:602
Mass (Da):65,715
Last modified:February 1, 1995 - v2
Checksum:i78B97716681FF50E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X61575 Genomic DNA. Translation: CAA43775.1.
U01159 Genomic DNA. Translation: AAC44192.1.
AP001918 Genomic DNA. Translation: BAA97959.1.
M60427 Genomic DNA. Translation: AAA24915.1.
PIRiS23991.
RefSeqiNP_061468.1. NC_002483.1.
WP_000821835.1. NC_002483.1.
YP_009073935.1. NG_034400.1.

Genome annotation databases

GeneIDi1263575.
KEGGipg:1263575.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X61575 Genomic DNA. Translation: CAA43775.1.
U01159 Genomic DNA. Translation: AAC44192.1.
AP001918 Genomic DNA. Translation: BAA97959.1.
M60427 Genomic DNA. Translation: AAA24915.1.
PIRiS23991.
RefSeqiNP_061468.1. NC_002483.1.
WP_000821835.1. NC_002483.1.
YP_009073935.1. NG_034400.1.

3D structure databases

ProteinModelPortaliP24082.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP24082.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1263575.
KEGGipg:1263575.

Phylogenomic databases

KOiK12058.
OMAiESCPFSK.

Miscellaneous databases

PROiP24082.

Family and domain databases

InterProiIPR014121. TraN_Ftype.
[Graphical view]
PfamiPF06986. TraN. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02750. TraN_Ftype. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of the F plasmid mating aggregation gene traN and of a new F transfer region locus trbE."
    Maneewannakul S., Kathir P., Ippen-Ihler K.
    J. Mol. Biol. 225:299-311(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION.
    Strain: K12.
  2. "Analysis of the sequence and gene products of the transfer region of the F sex factor."
    Frost L.S., Ippen-Ihler K., Skurray R.A.
    Microbiol. Rev. 58:162-210(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Complete nucleotide sequence of the F plasmid: its implications for organization and diversification of plasmid genomes."
    Shimizu H., Saitoh Y., Suda Y., Uehara K., Sampei G., Mizobuchi K.
    Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / CR63.
  4. "Characterization of trbC, a new F plasmid tra operon gene that is essential to conjugative transfer."
    Maneewannakul S., Maneewannakul K., Ippen-Ihler K.
    J. Bacteriol. 173:3872-3878(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19.
    Strain: K12.

Entry informationi

Entry nameiTRAN_ECOLI
AccessioniPrimary (citable) accession number: P24082
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: February 1, 1995
Last modified: June 24, 2015
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.