P24082 (TRAN_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein TraN

Gene names

Name:	traN
Ordered Locus Names:	ECOK12F089

Encoded on

Plasmid F

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	602 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Function	Essential for F plasmid conjugative transfer. May interact with the recipient cell surface to stabilize mating pairs initiated by F-pili. May interact with TraG.
Subcellular location	Cell outer membrane Ref.1.

Ontologies

Keywords
Biological process	Conjugation
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
Technical term	Plasmid
Gene Ontology (GO)
Biological_process	conjugation Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 602	584	Protein TraN		PRO_0000024508

Sequences

	Sequence		Length	Mass (Da)
	P24082 [UniParc]. Last modified February 1, 1995. Version 2. Checksum: 78B97716681FF50E	FASTA	602	65,715
	10 20 30 40 50 60 MKRILPLILA LVAGMAQADS NSDYRAGSDF AHQIKGQGSS SIQGFKPQES IPGYNANPDE 70 80 90 100 110 120 TKYYGGVTAG GDGGLKNDGT TEWATGETGK TITESFMNKP KDILSPDAPF IQTGRDVVNR 130 140 150 160 170 180 ADSIVGNTGQ QCSAQEISRS EYTNYTCERD LQVEQYCTRT ARMELQGSTT WETRTLEYEM 190 200 210 220 230 240 SQLPAREVNG QYVVSITSPV TGEIVDAHYS WSRTYLQKSV PMTITVLGTP LSWNAKYSAD 250 260 270 280 290 300 ASFTPVQKTL TAGVAFTSSH PVRVGNTKFK RHTAMKLRLV VRVKKASYTP YVVWSESCPF 310 320 330 340 350 360 SKELGKLTKT ECTEAGGNRT LVKDGQSYSM YQSCWAYRDT YVTQSADKGT CQTYTDNPAC 370 380 390 400 410 420 TLVSHQCAFY SEEGACLHEY ATYSCESKTS GKVMVCGGDV FCLDGECDKA QSGKSNDFAE 430 440 450 460 470 480 AVSQLAALAA AGKDVAALNG VDVRAFTGQA KFCKKAAAGY SNCCKDSGWG QDIGLAKCSS 490 500 510 520 530 540 DEKALAKAKS NKLTVSVGEF CSKKVLGVCL EKKRSYCQFD SKLAQIVQQQ GRNGQLRISF 550 560 570 580 590 600 GSAKHPDCRG ITVDELQKIQ FNRLDFTNFY EDLMNNQKIP DSGVLTQKVK EQIADQLKQA GQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of the F plasmid mating aggregation gene traN and of a new F transfer region locus trbE." Maneewannakul S., Kathir P., Ippen-Ihler K. J. Mol. Biol. 225:299-311(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION. Strain: K12.
[2]	"Analysis of the sequence and gene products of the transfer region of the F sex factor." Frost L.S., Ippen-Ihler K., Skurray R.A. Microbiol. Rev. 58:162-210(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Complete nucleotide sequence of the F plasmid: its implications for organization and diversification of plasmid genomes." Shimizu H., Saitoh Y., Suda Y., Uehara K., Sampei G., Mizobuchi K. Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / CR63.
[4]	"Characterization of trbC, a new F plasmid tra operon gene that is essential to conjugative transfer." Maneewannakul S., Maneewannakul K., Ippen-Ihler K. J. Bacteriol. 173:3872-3878(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19. Strain: K12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X61575 Genomic DNA. Translation: CAA43775.1. U01159 Genomic DNA. Translation: AAC44192.1. AP001918 Genomic DNA. Translation: BAA97959.1. M60427 Genomic DNA. Translation: AAA24915.1.
PIR	S23991.
RefSeq	NP_061468.1. NC_002483.1.
3D structure databases
ProteinModelPortal	P24082.
ModBase	Search...
Proteomic databases
PRIDE	P24082.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1263575.
Phylogenomic databases
OMA	ESCPFSK.
ProtClustDB	PRK12355.
Gene expression databases
Genevestigator	P24082.
Family and domain databases
InterPro	IPR014121. TraN_Ftype. [Graphical view]
Pfam	PF06986. TraN. 1 hit. [Graphical view]
TIGRFAMs	TIGR02750. TraN_Ftype. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRAN_ECOLI

Accession

Primary (citable) accession number: P24082

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 1992
Last sequence update:	February 1, 1995
Last modified:	May 1, 2013
This is version 73 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program