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Protein

Enterobactin exporter EntS

Gene

entS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Exports the siderophore enterobactin out of the cell.1 Publication

GO - Molecular functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoCyc
  • enterobactin transport Source: EcoliWiki
  • response to antibiotic Source: EcoCyc

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YBDA-MONOMER
MetaCyc:YBDA-MONOMER

Protein family/group databases

TCDBi2.A.1.38.1 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Enterobactin exporter EntS
Alternative name(s):
Protein p43
Gene namesi
Name:entS
Synonyms:ybdA
Ordered Locus Names:b0591, JW0583
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11104 entS

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 21PeriplasmicSequence analysisAdd BLAST21
Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Topological domaini43 – 55CytoplasmicSequence analysisAdd BLAST13
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Topological domaini77 – 95PeriplasmicSequence analysisAdd BLAST19
Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Topological domaini117 – 118CytoplasmicSequence analysis2
Transmembranei119 – 139HelicalSequence analysisAdd BLAST21
Topological domaini140 – 156PeriplasmicSequence analysisAdd BLAST17
Transmembranei157 – 177HelicalSequence analysisAdd BLAST21
Topological domaini178CytoplasmicSequence analysis1
Transmembranei179 – 199HelicalSequence analysisAdd BLAST21
Topological domaini200 – 218PeriplasmicSequence analysisAdd BLAST19
Transmembranei219 – 239HelicalSequence analysisAdd BLAST21
Topological domaini240 – 256CytoplasmicSequence analysisAdd BLAST17
Transmembranei257 – 277HelicalSequence analysisAdd BLAST21
Topological domaini278 – 300PeriplasmicSequence analysisAdd BLAST23
Transmembranei301 – 321HelicalSequence analysisAdd BLAST21
Topological domaini322 – 356CytoplasmicSequence analysisAdd BLAST35
Transmembranei357 – 377HelicalSequence analysisAdd BLAST21
Topological domaini378PeriplasmicSequence analysis1
Transmembranei379 – 399HelicalSequence analysisAdd BLAST21
Topological domaini400 – 416CytoplasmicSequence analysisAdd BLAST17

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001686611 – 416Enterobactin exporter EntSAdd BLAST416

Proteomic databases

PaxDbiP24077
PRIDEiP24077

Interactioni

Protein-protein interaction databases

BioGridi4260903, 384 interactors
STRINGi316385.ECDH10B_0659

Structurei

3D structure databases

ProteinModelPortaliP24077
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E8G Bacteria
COG0477 LUCA
HOGENOMiHOG000183770
InParanoidiP24077
KOiK08225
OMAiTPDDMRG
PhylomeDBiP24077

Family and domain databases

CDDicd06174 MFS, 1 hit
HAMAPiMF_01436 MFS_EntS, 1 hit
InterProiView protein in InterPro
IPR023722 Enterobactin_exp_EntS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR010290 TM_effector
PfamiView protein in Pfam
PF05977 MFS_3, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

P24077-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKQSWLLNL SLLKTHPAFR AVFLARFISI VSLGLLGVAV PVQIQMMTHS
60 70 80 90 100
TWQVGLSVTL TGGAMFVGLM VGGVLADRYE RKKVILLARG TCGIGFIGLC
110 120 130 140 150
LNALLPEPSL LAIYLLGLWD GFFASLGVTA LLAATPALVG RENLMQAGAI
160 170 180 190 200
TMLTVRLGSV ISPMIGGLLL ATGGVAWNYG LAAAGTFITL LPLLSLPALP
210 220 230 240 250
PPPQPREHPL KSLLAGFRFL LASPLVGGIA LLGGLLTMAS AVRVLYPALA
260 270 280 290 300
DNWQMSAAQI GFLYAAIPLG AAIGALTSGK LAHSARPGLL MLLSTLGSFL
310 320 330 340 350
AIGLFGLMPM WILGVVCLAL FGWLSAVSSL LQYTMLQTQT PEAMLGRING
360 370 380 390 400
LWTAQNVTGD AIGAALLGGL GAMMTPVASA SASGFGLLII GVLLLLVLVE
410
LRHFRQTPPQ VTASDS
Length:416
Mass (Da):43,282
Last modified:November 1, 1997 - v2
Checksum:i64FCCF9AF99AC25A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti123F → S in CAA40706 (PubMed:1838574).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57470 Genomic DNA Translation: CAA40706.1
X59402 Genomic DNA Translation: CAA42044.1
U82598 Genomic DNA Translation: AAB40790.1
U00096 Genomic DNA Translation: AAC73692.1
AP009048 Genomic DNA Translation: BAE76346.1
PIRiS16306
RefSeqiNP_415123.1, NC_000913.3
WP_001041786.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73692; AAC73692; b0591
BAE76346; BAE76346; BAE76346
GeneIDi946268
KEGGiecj:JW0583
eco:b0591
PATRICifig|1411691.4.peg.1678

Similar proteinsi

Entry informationi

Entry nameiENTS_ECOLI
AccessioniPrimary (citable) accession number: P24077
Secondary accession number(s): Q2MBL0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health