Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Enterobactin exporter EntS

Gene

entS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Exports the siderophore enterobactin out of the cell.1 Publication

GO - Molecular functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoCyc
  • enterobactin transport Source: EcoliWiki
  • response to antibiotic Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YBDA-MONOMER.
ECOL316407:JW0583-MONOMER.
MetaCyc:YBDA-MONOMER.

Protein family/group databases

TCDBi2.A.1.38.1. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Enterobactin exporter EntS
Alternative name(s):
Protein p43
Gene namesi
Name:entS
Synonyms:ybdA
Ordered Locus Names:b0591, JW0583
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11104. entS.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 21PeriplasmicSequence analysisAdd BLAST21
Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Topological domaini43 – 55CytoplasmicSequence analysisAdd BLAST13
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Topological domaini77 – 95PeriplasmicSequence analysisAdd BLAST19
Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Topological domaini117 – 118CytoplasmicSequence analysis2
Transmembranei119 – 139HelicalSequence analysisAdd BLAST21
Topological domaini140 – 156PeriplasmicSequence analysisAdd BLAST17
Transmembranei157 – 177HelicalSequence analysisAdd BLAST21
Topological domaini178CytoplasmicSequence analysis1
Transmembranei179 – 199HelicalSequence analysisAdd BLAST21
Topological domaini200 – 218PeriplasmicSequence analysisAdd BLAST19
Transmembranei219 – 239HelicalSequence analysisAdd BLAST21
Topological domaini240 – 256CytoplasmicSequence analysisAdd BLAST17
Transmembranei257 – 277HelicalSequence analysisAdd BLAST21
Topological domaini278 – 300PeriplasmicSequence analysisAdd BLAST23
Transmembranei301 – 321HelicalSequence analysisAdd BLAST21
Topological domaini322 – 356CytoplasmicSequence analysisAdd BLAST35
Transmembranei357 – 377HelicalSequence analysisAdd BLAST21
Topological domaini378PeriplasmicSequence analysis1
Transmembranei379 – 399HelicalSequence analysisAdd BLAST21
Topological domaini400 – 416CytoplasmicSequence analysisAdd BLAST17

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001686611 – 416Enterobactin exporter EntSAdd BLAST416

Proteomic databases

PaxDbiP24077.
PRIDEiP24077.

Interactioni

Protein-protein interaction databases

BioGridi4260903. 371 interactors.
STRINGi511145.b0591.

Structurei

3D structure databases

ProteinModelPortaliP24077.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E8G. Bacteria.
COG0477. LUCA.
HOGENOMiHOG000183770.
InParanoidiP24077.
KOiK08225.
OMAiLLGIWDG.
PhylomeDBiP24077.

Family and domain databases

CDDicd06174. MFS. 1 hit.
HAMAPiMF_01436. MFS_EntS. 1 hit.
InterProiIPR023722. Enterobactin_exp_EntS.
IPR020846. MFS_dom.
IPR010290. TM_effector.
[Graphical view]
PfamiPF05977. MFS_3. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24077-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKQSWLLNL SLLKTHPAFR AVFLARFISI VSLGLLGVAV PVQIQMMTHS
60 70 80 90 100
TWQVGLSVTL TGGAMFVGLM VGGVLADRYE RKKVILLARG TCGIGFIGLC
110 120 130 140 150
LNALLPEPSL LAIYLLGLWD GFFASLGVTA LLAATPALVG RENLMQAGAI
160 170 180 190 200
TMLTVRLGSV ISPMIGGLLL ATGGVAWNYG LAAAGTFITL LPLLSLPALP
210 220 230 240 250
PPPQPREHPL KSLLAGFRFL LASPLVGGIA LLGGLLTMAS AVRVLYPALA
260 270 280 290 300
DNWQMSAAQI GFLYAAIPLG AAIGALTSGK LAHSARPGLL MLLSTLGSFL
310 320 330 340 350
AIGLFGLMPM WILGVVCLAL FGWLSAVSSL LQYTMLQTQT PEAMLGRING
360 370 380 390 400
LWTAQNVTGD AIGAALLGGL GAMMTPVASA SASGFGLLII GVLLLLVLVE
410
LRHFRQTPPQ VTASDS
Length:416
Mass (Da):43,282
Last modified:November 1, 1997 - v2
Checksum:i64FCCF9AF99AC25A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti123F → S in CAA40706 (PubMed:1838574).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57470 Genomic DNA. Translation: CAA40706.1.
X59402 Genomic DNA. Translation: CAA42044.1.
U82598 Genomic DNA. Translation: AAB40790.1.
U00096 Genomic DNA. Translation: AAC73692.1.
AP009048 Genomic DNA. Translation: BAE76346.1.
PIRiS16306.
RefSeqiNP_415123.1. NC_000913.3.
WP_001041786.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73692; AAC73692; b0591.
BAE76346; BAE76346; BAE76346.
GeneIDi946268.
KEGGiecj:JW0583.
eco:b0591.
PATRICi32116358. VBIEscCol129921_0619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57470 Genomic DNA. Translation: CAA40706.1.
X59402 Genomic DNA. Translation: CAA42044.1.
U82598 Genomic DNA. Translation: AAB40790.1.
U00096 Genomic DNA. Translation: AAC73692.1.
AP009048 Genomic DNA. Translation: BAE76346.1.
PIRiS16306.
RefSeqiNP_415123.1. NC_000913.3.
WP_001041786.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP24077.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260903. 371 interactors.
STRINGi511145.b0591.

Protein family/group databases

TCDBi2.A.1.38.1. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP24077.
PRIDEiP24077.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73692; AAC73692; b0591.
BAE76346; BAE76346; BAE76346.
GeneIDi946268.
KEGGiecj:JW0583.
eco:b0591.
PATRICi32116358. VBIEscCol129921_0619.

Organism-specific databases

EchoBASEiEB1096.
EcoGeneiEG11104. entS.

Phylogenomic databases

eggNOGiENOG4105E8G. Bacteria.
COG0477. LUCA.
HOGENOMiHOG000183770.
InParanoidiP24077.
KOiK08225.
OMAiLLGIWDG.
PhylomeDBiP24077.

Enzyme and pathway databases

BioCyciEcoCyc:YBDA-MONOMER.
ECOL316407:JW0583-MONOMER.
MetaCyc:YBDA-MONOMER.

Miscellaneous databases

PROiP24077.

Family and domain databases

CDDicd06174. MFS. 1 hit.
HAMAPiMF_01436. MFS_EntS. 1 hit.
InterProiIPR023722. Enterobactin_exp_EntS.
IPR020846. MFS_dom.
IPR010290. TM_effector.
[Graphical view]
PfamiPF05977. MFS_3. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiENTS_ECOLI
AccessioniPrimary (citable) accession number: P24077
Secondary accession number(s): Q2MBL0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 123 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.