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Protein

Denitrification system component NirT

Gene

nirT

Organism
Pseudomonas stutzeri (Pseudomonas perfectomarina)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei58Heme 1 (covalent)By similarity1
Binding sitei61Heme 1 (covalent)By similarity1
Metal bindingi62Iron (heme 1 axial ligand)By similarity1
Binding sitei88Heme 2 (covalent)By similarity1
Binding sitei91Heme 2 (covalent)By similarity1
Metal bindingi92Iron (heme 2 axial ligand)By similarity1
Binding sitei148Heme 3 (covalent)By similarity1
Binding sitei151Heme 3 (covalent)By similarity1
Metal bindingi152Iron (heme 3 axial ligand)By similarity1
Binding sitei180Heme 4 (covalent)By similarity1
Binding sitei183Heme 4 (covalent)By similarity1
Metal bindingi184Iron (heme 4 axial ligand)By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Denitrification system component NirT
Gene namesi
Name:nirT
OrganismiPseudomonas stutzeri (Pseudomonas perfectomarina)
Taxonomic identifieri316 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 201PeriplasmicSequence analysisAdd BLAST156

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001084381 – 201Denitrification system component NirTAdd BLAST201

Post-translational modificationi

Binds 4 heme groups per subunit.

Expressioni

Inductioni

By anaerobic conditions.

Interactioni

Protein-protein interaction databases

STRINGi379731.PST_3531.

Structurei

3D structure databases

ProteinModelPortaliP24038.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CUW. Bacteria.
COG3005. LUCA.

Family and domain databases

InterProiIPR011031. Multihaem_cyt.
IPR024717. NapC/NirT/NrfH.
IPR005126. NapC/NirT_cyt_c_N.
IPR011885. NO3Rdtase_cyt_c_NapC/NirT.
[Graphical view]
PfamiPF03264. Cytochrom_NNT. 1 hit.
[Graphical view]
PIRSFiPIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
SUPFAMiSSF48695. SSF48695. 1 hit.
TIGRFAMsiTIGR02161. napC_nirT. 1 hit.
PROSITEiPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24038-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKDGNKQQ KGGILALLRR PSTRYSLGGI LIVGIVAGIV FWGGFNTALE
60 70 80 90 100
ATNTETFCIS CHEMGDNVYP EYKETIHYAN RTGVRATCPD CHVPRDWTHK
110 120 130 140 150
MVRKVEASKE LWGKIVGTID TAEKFEAKRL TLARREWARM RASDSRECRN
160 170 180 190 200
CHSLESMSSD MQKQRARKQH EMAREDNLTC IACHKGIAHH LPEGMTEEDE

D
Length:201
Mass (Da):22,825
Last modified:March 1, 1992 - v1
Checksum:i68B20780C422A450
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53676 Genomic DNA. Translation: CAA40151.1.
PIRiS13937. O4PSZ.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53676 Genomic DNA. Translation: CAA40151.1.
PIRiS13937. O4PSZ.

3D structure databases

ProteinModelPortaliP24038.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi379731.PST_3531.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105CUW. Bacteria.
COG3005. LUCA.

Family and domain databases

InterProiIPR011031. Multihaem_cyt.
IPR024717. NapC/NirT/NrfH.
IPR005126. NapC/NirT_cyt_c_N.
IPR011885. NO3Rdtase_cyt_c_NapC/NirT.
[Graphical view]
PfamiPF03264. Cytochrom_NNT. 1 hit.
[Graphical view]
PIRSFiPIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
SUPFAMiSSF48695. SSF48695. 1 hit.
TIGRFAMsiTIGR02161. napC_nirT. 1 hit.
PROSITEiPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNIRT_PSEST
AccessioniPrimary (citable) accession number: P24038
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: October 5, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.