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Protein

Denitrification system component NirT

Gene

nirT

Organism
Pseudomonas stutzeri (Pseudomonas perfectomarina)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei58Heme 1 (covalent)By similarity1
Binding sitei61Heme 1 (covalent)By similarity1
Metal bindingi64Iron (heme 1 axial ligand)By similarity1
Binding sitei88Heme 2 (covalent)By similarity1
Binding sitei91Heme 2 (covalent)By similarity1
Metal bindingi92Iron (heme 2 axial ligand); via tele nitrogenBy similarity1
Binding sitei104SubstrateBy similarity1
Metal bindingi110Iron (heme 1 axial ligand)By similarity1
Binding sitei148Heme 3 (covalent)By similarity1
Binding sitei151Heme 3 (covalent)By similarity1
Metal bindingi152Iron (heme 3 axial ligand); via tele nitrogenBy similarity1
Binding sitei180Heme 4 (covalent)By similarity1
Binding sitei183Heme 4 (covalent)By similarity1
Metal bindingi184Iron (heme 4 axial ligand); via tele nitrogenBy similarity1
Metal bindingi189Iron (heme 2 axial ligand); via tele nitrogenBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Denitrification system component NirT
Gene namesi
Name:nirT
OrganismiPseudomonas stutzeri (Pseudomonas perfectomarina)
Taxonomic identifieri316 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 201PeriplasmicSequence analysisAdd BLAST156

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001084381 – 201Denitrification system component NirTAdd BLAST201

Post-translational modificationi

Binds 4 heme groups per subunit.

Expressioni

Inductioni

By anaerobic conditions.

Interactioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei175Interaction with NrfABy similarity1

Structurei

3D structure databases

ProteinModelPortaliP24038
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CUW Bacteria
COG3005 LUCA

Family and domain databases

Gene3Di1.10.3820.10, 1 hit
InterProiView protein in InterPro
IPR011031 Multihaem_cyt
IPR036280 Multihaem_cyt_sf
IPR024717 NapC/NirT/NrfH
IPR005126 NapC/NirT_cyt_c_N
IPR038266 NapC/NirT_cytc_sf
IPR011885 NO3Rdtase_cyt_c_NapC/NirT
PfamiView protein in Pfam
PF03264 Cytochrom_NNT, 1 hit
PIRSFiPIRSF000013 4_hem_cytochrm_NapC, 1 hit
SUPFAMiSSF48695 SSF48695, 1 hit
TIGRFAMsiTIGR02161 napC_nirT, 1 hit
PROSITEiView protein in PROSITE
PS51008 MULTIHEME_CYTC, 1 hit

Sequencei

Sequence statusi: Complete.

P24038-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKDGNKQQ KGGILALLRR PSTRYSLGGI LIVGIVAGIV FWGGFNTALE
60 70 80 90 100
ATNTETFCIS CHEMGDNVYP EYKETIHYAN RTGVRATCPD CHVPRDWTHK
110 120 130 140 150
MVRKVEASKE LWGKIVGTID TAEKFEAKRL TLARREWARM RASDSRECRN
160 170 180 190 200
CHSLESMSSD MQKQRARKQH EMAREDNLTC IACHKGIAHH LPEGMTEEDE

D
Length:201
Mass (Da):22,825
Last modified:March 1, 1992 - v1
Checksum:i68B20780C422A450
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53676 Genomic DNA Translation: CAA40151.1
PIRiS13937 O4PSZ

Similar proteinsi

Entry informationi

Entry nameiNIRT_PSEST
AccessioniPrimary (citable) accession number: P24038
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: April 25, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health