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Protein

Cytochrome c oxidase subunit 4B

Gene

ctaF

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciBSUB:BSU14920-MONOMER.

Protein family/group databases

TCDBi3.D.4.4.1. the proton-translocating cytochrome oxidase (cox) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 4B (EC:1.9.3.1)
Alternative name(s):
Caa-3605 subunit 4B
Cytochrome aa3 subunit 4B
Cytochrome c oxidase polypeptide IVB
Gene namesi
Name:ctaF
Ordered Locus Names:BSU14920
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570 Componenti: Chromosome

Organism-specific databases

GenoListiBSU14920. [Micado]

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei27 – 4721HelicalSequence AnalysisAdd
BLAST
Transmembranei50 – 7021HelicalSequence AnalysisAdd
BLAST
Transmembranei88 – 10821HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 110110Cytochrome c oxidase subunit 4BPRO_0000183902Add
BLAST

Proteomic databases

PaxDbiP24013.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100008256.

Structurei

3D structure databases

ProteinModelPortaliP24013.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3125.
HOGENOMiHOG000261855.
KOiK02277.
OMAiNAEEMKH.
OrthoDBiEOG6JX7N4.

Family and domain databases

InterProiIPR014257. Cyt_c_oxidase_su4_bacillaceae.
IPR005171. Cyt_c_oxidase_su4_prok.
[Graphical view]
PfamiPF03626. COX4_pro. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02908. CoxD_Bacillus. 1 hit.

Sequencei

Sequence statusi: Complete.

P24013-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDKKSRGHI NSDLEFKKKK HAREMKYQVL SFGLMIGLTI VAFLTVATDG
60 70 80 90 100
VGSWFTIPFI ILLAAIQVIF QLYYFMHMNQ KGHEAPALFL YSGVFVAFIT
110
VLAFVTIIWW
Length:110
Mass (Da):12,620
Last modified:March 1, 1992 - v1
Checksum:i1142CF36A63C3AF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54140 Genomic DNA. Translation: CAA38079.1.
Z98682 Genomic DNA. Translation: CAB11345.1.
AL009126 Genomic DNA. Translation: CAB13365.1.
PIRiG69609.
RefSeqiNP_389375.1. NC_000964.3.
WP_003232242.1. NZ_JNCM01000035.1.

Genome annotation databases

EnsemblBacteriaiCAB13365; CAB13365; BSU14920.
GeneIDi936259.
KEGGibsu:BSU14920.
PATRICi18974785. VBIBacSub10457_1584.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54140 Genomic DNA. Translation: CAA38079.1.
Z98682 Genomic DNA. Translation: CAB11345.1.
AL009126 Genomic DNA. Translation: CAB13365.1.
PIRiG69609.
RefSeqiNP_389375.1. NC_000964.3.
WP_003232242.1. NZ_JNCM01000035.1.

3D structure databases

ProteinModelPortaliP24013.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100008256.

Protein family/group databases

TCDBi3.D.4.4.1. the proton-translocating cytochrome oxidase (cox) superfamily.

Proteomic databases

PaxDbiP24013.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB13365; CAB13365; BSU14920.
GeneIDi936259.
KEGGibsu:BSU14920.
PATRICi18974785. VBIBacSub10457_1584.

Organism-specific databases

GenoListiBSU14920. [Micado]

Phylogenomic databases

eggNOGiCOG3125.
HOGENOMiHOG000261855.
KOiK02277.
OMAiNAEEMKH.
OrthoDBiEOG6JX7N4.

Enzyme and pathway databases

BioCyciBSUB:BSU14920-MONOMER.

Family and domain databases

InterProiIPR014257. Cyt_c_oxidase_su4_bacillaceae.
IPR005171. Cyt_c_oxidase_su4_prok.
[Graphical view]
PfamiPF03626. COX4_pro. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02908. CoxD_Bacillus. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The Bacillus subtilis cytochrome-c oxidase. Variations on a conserved protein theme."
    Saraste M., Metso T., Nakari T., Jalli T., Lauraeus M., van der Oost J.
    Eur. J. Biochem. 195:517-525(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  2. "Bacillus subtilis chromosomal region downstream nprE."
    Bertero M., Presecan E., Glaser P., Richou A., Danchin A.
    Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  3. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.

Entry informationi

Entry nameiCOX4_BACSU
AccessioniPrimary (citable) accession number: P24013
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: July 22, 2015
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.