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P24012

- COX3_BACSU

UniProt

P24012 - COX3_BACSU

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Protein

Cytochrome c oxidase subunit 3

Gene

ctaE

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciBSUB:BSU14910-MONOMER.

Protein family/group databases

TCDBi3.D.4.4.1. the proton-translocating cytochrome oxidase (cox) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Caa-3605 subunit 3
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Oxidase aa(3) subunit 3
Gene namesi
Name:ctaE
Ordered Locus Names:BSU14910
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570: Chromosome

Organism-specific databases

GenoListiBSU14910. [Micado]

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei30 – 5021HelicalSequence AnalysisAdd
BLAST
Transmembranei67 – 8721HelicalSequence AnalysisAdd
BLAST
Transmembranei101 – 12121HelicalSequence AnalysisAdd
BLAST
Transmembranei144 – 16421HelicalSequence AnalysisAdd
BLAST
Transmembranei186 – 20621HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 207207Cytochrome c oxidase subunit 3PRO_0000183877Add
BLAST

Proteomic databases

PaxDbiP24012.

Interactioni

Protein-protein interaction databases

STRINGi224308.BSU14910.

Structurei

3D structure databases

ProteinModelPortaliP24012.
SMRiP24012. Positions 20-205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1845.
HOGENOMiHOG000086398.
InParanoidiP24012.
KOiK02276.
OMAiHYTHEFG.
OrthoDBiEOG6SFPBZ.
PhylomeDBiP24012.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P24012-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQVQEKFTAE TFPASPEKVT LEGKNKFLGF WLFLGGETVL FASLFATFLA
60 70 80 90 100
LRNSNAGDPP TTEMFDVTLV FIATMLLLTS SLTSVYAMYH MKNFSFGKMQ
110 120 130 140 150
LWLGITILLG AGFLGLEIYE FKHYTHEFGF TITSSALGSA FYTLVGTHGA
160 170 180 190 200
HVAFGLMWIS TLMIRNAKRG LNLYTAPKFY VASLYWHFID VVWVFIFTVV

YLMGMVG
Length:207
Mass (Da):23,266
Last modified:May 30, 2000 - v2
Checksum:i9357E3DDAB137F12
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti26 – 261K → N in CAA38078. (PubMed:1847686)Curated
Sequence conflicti51 – 522LR → AS in CAA38078. (PubMed:1847686)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54140 Genomic DNA. Translation: CAA38078.1.
Z98682 Genomic DNA. Translation: CAB11344.1.
AL009126 Genomic DNA. Translation: CAB13364.1.
PIRiF69609.
RefSeqiNP_389374.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB13364; CAB13364; BSU14910.
GeneIDi935993.
KEGGibsu:BSU14910.
PATRICi18974783. VBIBacSub10457_1583.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54140 Genomic DNA. Translation: CAA38078.1 .
Z98682 Genomic DNA. Translation: CAB11344.1 .
AL009126 Genomic DNA. Translation: CAB13364.1 .
PIRi F69609.
RefSeqi NP_389374.1. NC_000964.3.

3D structure databases

ProteinModelPortali P24012.
SMRi P24012. Positions 20-205.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224308.BSU14910.

Protein family/group databases

TCDBi 3.D.4.4.1. the proton-translocating cytochrome oxidase (cox) superfamily.

Proteomic databases

PaxDbi P24012.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB13364 ; CAB13364 ; BSU14910 .
GeneIDi 935993.
KEGGi bsu:BSU14910.
PATRICi 18974783. VBIBacSub10457_1583.

Organism-specific databases

GenoListi BSU14910. [Micado ]

Phylogenomic databases

eggNOGi COG1845.
HOGENOMi HOG000086398.
InParanoidi P24012.
KOi K02276.
OMAi HYTHEFG.
OrthoDBi EOG6SFPBZ.
PhylomeDBi P24012.

Enzyme and pathway databases

BioCyci BSUB:BSU14910-MONOMER.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The Bacillus subtilis cytochrome-c oxidase. Variations on a conserved protein theme."
    Saraste M., Metso T., Nakari T., Jalli T., Lauraeus M., van der Oost J.
    Eur. J. Biochem. 195:517-525(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  2. "Bacillus subtilis chromosomal region downstream nprE."
    Bertero M., Presecan E., Glaser P., Richou A., Danchin A.
    Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  3. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.

Entry informationi

Entry nameiCOX3_BACSU
AccessioniPrimary (citable) accession number: P24012
Secondary accession number(s): O34333
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: May 30, 2000
Last modified: October 29, 2014
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3