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P24012

- COX3_BACSU

UniProt

P24012 - COX3_BACSU

Protein

Cytochrome c oxidase subunit 3

Gene

ctaE

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 107 (01 Oct 2014)
      Sequence version 2 (30 May 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciBSUB:BSU14910-MONOMER.

    Protein family/group databases

    TCDBi3.D.4.4.1. the proton-translocating cytochrome oxidase (cox) superfamily.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Caa-3605 subunit 3
    Cytochrome aa3 subunit 3
    Cytochrome c oxidase polypeptide III
    Oxidase aa(3) subunit 3
    Gene namesi
    Name:ctaE
    Ordered Locus Names:BSU14910
    OrganismiBacillus subtilis (strain 168)
    Taxonomic identifieri224308 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001570: Chromosome

    Organism-specific databases

    GenoListiBSU14910. [Micado]

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 207207Cytochrome c oxidase subunit 3PRO_0000183877Add
    BLAST

    Proteomic databases

    PaxDbiP24012.

    Interactioni

    Protein-protein interaction databases

    STRINGi224308.BSU14910.

    Structurei

    3D structure databases

    ProteinModelPortaliP24012.
    SMRiP24012. Positions 20-205.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei30 – 5021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei67 – 8721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei101 – 12121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei144 – 16421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei186 – 20621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1845.
    HOGENOMiHOG000086398.
    KOiK02276.
    OMAiHYTHEFG.
    OrthoDBiEOG6SFPBZ.
    PhylomeDBiP24012.

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P24012-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQVQEKFTAE TFPASPEKVT LEGKNKFLGF WLFLGGETVL FASLFATFLA    50
    LRNSNAGDPP TTEMFDVTLV FIATMLLLTS SLTSVYAMYH MKNFSFGKMQ 100
    LWLGITILLG AGFLGLEIYE FKHYTHEFGF TITSSALGSA FYTLVGTHGA 150
    HVAFGLMWIS TLMIRNAKRG LNLYTAPKFY VASLYWHFID VVWVFIFTVV 200
    YLMGMVG 207
    Length:207
    Mass (Da):23,266
    Last modified:May 30, 2000 - v2
    Checksum:i9357E3DDAB137F12
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti26 – 261K → N in CAA38078. (PubMed:1847686)Curated
    Sequence conflicti51 – 522LR → AS in CAA38078. (PubMed:1847686)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54140 Genomic DNA. Translation: CAA38078.1.
    Z98682 Genomic DNA. Translation: CAB11344.1.
    AL009126 Genomic DNA. Translation: CAB13364.1.
    PIRiF69609.
    RefSeqiNP_389374.1. NC_000964.3.

    Genome annotation databases

    EnsemblBacteriaiCAB13364; CAB13364; BSU14910.
    GeneIDi935993.
    KEGGibsu:BSU14910.
    PATRICi18974783. VBIBacSub10457_1583.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54140 Genomic DNA. Translation: CAA38078.1 .
    Z98682 Genomic DNA. Translation: CAB11344.1 .
    AL009126 Genomic DNA. Translation: CAB13364.1 .
    PIRi F69609.
    RefSeqi NP_389374.1. NC_000964.3.

    3D structure databases

    ProteinModelPortali P24012.
    SMRi P24012. Positions 20-205.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224308.BSU14910.

    Protein family/group databases

    TCDBi 3.D.4.4.1. the proton-translocating cytochrome oxidase (cox) superfamily.

    Proteomic databases

    PaxDbi P24012.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB13364 ; CAB13364 ; BSU14910 .
    GeneIDi 935993.
    KEGGi bsu:BSU14910.
    PATRICi 18974783. VBIBacSub10457_1583.

    Organism-specific databases

    GenoListi BSU14910. [Micado ]

    Phylogenomic databases

    eggNOGi COG1845.
    HOGENOMi HOG000086398.
    KOi K02276.
    OMAi HYTHEFG.
    OrthoDBi EOG6SFPBZ.
    PhylomeDBi P24012.

    Enzyme and pathway databases

    BioCyci BSUB:BSU14910-MONOMER.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Bacillus subtilis cytochrome-c oxidase. Variations on a conserved protein theme."
      Saraste M., Metso T., Nakari T., Jalli T., Lauraeus M., van der Oost J.
      Eur. J. Biochem. 195:517-525(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168.
    2. "Bacillus subtilis chromosomal region downstream nprE."
      Bertero M., Presecan E., Glaser P., Richou A., Danchin A.
      Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168.
    3. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
      Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
      , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
      Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 168.

    Entry informationi

    Entry nameiCOX3_BACSU
    AccessioniPrimary (citable) accession number: P24012
    Secondary accession number(s): O34333
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 1992
    Last sequence update: May 30, 2000
    Last modified: October 1, 2014
    This is version 107 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Bacillus subtilis
      Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3