ID   FSHR_HUMAN     STANDARD;      PRT;   695 AA.
AC   P23945;
DT   01-MAR-1992 (REL. 21, CREATED)
DT   01-MAR-1992 (REL. 21, LAST SEQUENCE UPDATE)
DT   01-MAR-1992 (REL. 21, LAST ANNOTATION UPDATE)
DE   FOLLICLE STIMULATING HORMONE RECEPTOR PRECURSOR (FSH-R).
GN   FSHR.
OS   HOMO SAPIENS (HUMAN).
OC   EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA;
OC   EUTHERIA; PRIMATES.
RN   [1]
RP   SEQUENCE FROM N.A.
RM   91222171
RA   MINEGISH T., NAKAMURA K., TAKAKURA Y., IBUKI Y., IGARASHI M.;
RL   BIOCHEM. BIOPHYS. RES. COMMUN. 175:1125-1130(1991).
CC   -!- FUNCTION: RECEPTOR FOR FOLLICLE STIMULATING HORMONE.
CC   -!- SIMILARITY: HIGHLY SIMILAR TO LSH AND TSH RECEPTORS.
CC   -!- SIMILARITY: DISTANTLY RELATED TO OTHER G-PROTEIN COUPLED
CC       RECEPTORS.
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DR   EMBL; M65085; HSFSHRE.
DR   PIR; JN0122; JN0122.
DR   MIM; 136435; TENTH EDITION.
KW   G-PROTEIN COUPLED RECEPTOR; TRANSMEMBRANE; GLYCOPROTEIN; SIGNAL;
KW   PHOSPHORYLATION.
FT   SIGNAL        1     17       POTENTIAL.
FT   CHAIN        18    695       FOLLICLE STIMULATING HORMONE RECEPTOR.
FT   TRANSMEM    367    387       1 (POTENTIAL).
FT   DOMAIN      388    398       CYTOPLASMIC (POTENTIAL).
FT   TRANSMEM    399    421       2 (POTENTIAL).
FT   DOMAIN      422    443       EXTRACELLULAR (POTENTIAL).
FT   TRANSMEM    444    465       3 (POTENTIAL).
FT   DOMAIN      466    485       CYTOPLASMIC (POTENTIAL).
FT   TRANSMEM    486    508       4 (POTENTIAL).
FT   DOMAIN      509    528       EXTRACELLULAR (POTENTIAL).
FT   TRANSMEM    529    550       5 (POTENTIAL).
FT   DOMAIN      551    573       CYTOPLASMIC (POTENTIAL).
FT   TRANSMEM    574    597       6 (POTENTIAL).
FT   DOMAIN      598    608       EXTRACELLULAR (POTENTIAL).
FT   TRANSMEM    609    630       7 (POTENTIAL).
FT   DOMAIN      631    695       CYTOPLASMIC (POTENTIAL).
FT   CARBOHYD    191    191       POTENTIAL.
FT   CARBOHYD    199    199       POTENTIAL.
FT   CARBOHYD    293    293       POTENTIAL.
FT   CARBOHYD    318    318       POTENTIAL.
FT   DISULFID    442    517       BY SIMILARITY.
SQ   SEQUENCE   695 AA;  78152 MW;  2586697 CN;
     MALLLVSLLA FLSLGSGCHH RICHCSNRVF LCQESKVTEI PSDLPRNAIE LRFVLTKLRV
     IQKGAFSGFG DLEKIEISQN DVLEVIEADV FSNLPKLHEI RIEKANNLLY ITPEAFQNLP
     NLQYLLISNT GIKHLPDVHK IHSLQKVLLD IQDNINIHTI ERNSFVGLSF ESVILWLNKN
     GIQEIHNCAF NGTQLDAVNL SDNNNLEELP NDVFHGASGP VILDISRTRI HSLPSYGLEN
     LKKLRARSTY NLKKLPTLEK LVALMEASLT YPSHCCAFAN WRRQISELHP ICNKSILRQE
     VDYMTQARGQ RSSLAEDNES SYSRGFDMTY TEFDYDLCNE VVDVTCSPKP DAFNPCEDIM
     GYNILRVLIW FISILAITGN IIVLVILTTS QYKLTVPRFL MCNLAFADLC IGIYLLLIAS
     VDIHTKSQYH NYAIDWQTGA GCDAAGFFTV FASELSVYTL TAITLERWHT ITHAMQLDCK
     VQLRHAASVM VMGWIFAFAA ALFPIFGISS YMKVSICLPM DIDSPLSQLY VMSLLVLNVL
     AFVVICGCYI HIYLTVRNPN IVSSSSDTRI AKRMAMLIFT DFLCMAPISF FAISASLKVP
     LITVSKAKIL LVLFHPINSC ANPFLYAIFT KNFRRDFFIL LSKCGCYEMQ AQIYRTETSS
     TVHNTHPRNG HCSSAPRVTS GSTYILVPLS HLAQN
//