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P23926 (ANR_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 101. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Transcriptional activator protein anr
Gene names
Name:anr
Ordered Locus Names:PA1544
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length244 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Transcriptional activator of anaerobic gene expression.

Miscellaneous

Possesses 4 cysteines which may bind a metal ion (possibly iron).

Sequence similarities

Contains 1 cyclic nucleotide-binding domain.

Contains 1 HTH crp-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 244244Transcriptional activator protein anr
PRO_0000100142

Regions

Domain159 – 23274HTH crp-type
Nucleotide binding21 – 149129cNMP
DNA binding192 – 21120H-T-H motif By similarity

Sequences

Sequence LengthMass (Da)Tools
P23926 [UniParc].

Last modified March 1, 1992. Version 1.
Checksum: A57E6C0CFB32600B

FASTA24427,129
        10         20         30         40         50         60 
MAETIKVRAL PQAHCKDCSL APLCLPLSLT VEDMDSLDEI VKRGRPLKKG EFLFRQGDPF 

        70         80         90        100        110        120 
GSVFAVRSGA LKTFSITDAG EEQITGFHLP SELVGLSGMD TETYPVSAQA LETTSVCEIP 

       130        140        150        160        170        180 
FERLDELSEQ LPQLRRQLMR LMSREIRDDQ QMMLLLSKKT ADERIATFLV NLSARFRARG 

       190        200        210        220        230        240 
FSAQQFRLAM SRNEIGNYLG LAVETVSRVF TRFQQNGLIS AEGKEVHILD SIELCALAGG 


QLEG 

« Hide

References

« Hide 'large scale' references
[1]"Identification and molecular characterization of a transcriptional regulator from Pseudomonas aeruginosa PAO1 exhibiting structural and functional similarity to the FNR protein of Escherichia coli."
Sawers R.G.
Mol. Microbiol. 5:1469-1481(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]"Anaerobic growth and cyanide synthesis of Pseudomonas aeruginosa depend on anr, a regulatory gene homologous with fnr of Escherichia coli."
Zimmermann A., Reimmann C., Galimand M., Haas D.
Mol. Microbiol. 5:1483-1490(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[3]"RpoN-independent promoters having a conserved GG-N10-GC motif in Pseudomonas aeruginosa."
Savioz A., Zimmermann A., Haas D.
Submitted (JAN-1993) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[4]"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen."
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. expand/collapse author list , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.
Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X58405 Genomic DNA. Translation: CAA41305.1.
X57736 Genomic DNA. Translation: CAA40906.1.
M98276 Genomic DNA. Translation: AAA25713.1.
AE004091 Genomic DNA. Translation: AAG04933.1.
PIRS16307.
RefSeqNP_250235.1. NC_002516.2.

3D structure databases

ProteinModelPortalP23926.
SMRP23926. Positions 8-230.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA1544.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG04933; AAG04933; PA1544.
GeneID883009.
KEGGpae:PA1544.
PATRIC19837422. VBIPseAer58763_1597.

Organism-specific databases

PseudoCAPPA1544.

Phylogenomic databases

eggNOGCOG0664.
HOGENOMHOG000186461.
KOK01420.
OMAFSANQFR.
OrthoDBEOG6RVFWF.
PhylomeDBP23926.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view]
PRINTSPR00034. HTHCRP.
SMARTSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMSSF51206. SSF51206. 1 hit.
PROSITEPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameANR_PSEAE
AccessionPrimary (citable) accession number: P23926
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: July 9, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families