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P23926

- ANR_PSEAE

UniProt

P23926 - ANR_PSEAE

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Protein
Transcriptional activator protein anr
Gene
anr, PA1544
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed - Annotation score: 4 out of 5 - Protein predictedi

Functioni

Transcriptional activator of anaerobic gene expression.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 149129cNMP
Add
BLAST
DNA bindingi192 – 21120H-T-H motif By similarity
Add
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding transcription factor activity Source: InterPro
  2. transcription regulatory region DNA binding Source: PseudoCAP

GO - Biological processi

  1. cellular response to decreased oxygen levels Source: PseudoCAP
  2. cyanide biosynthetic process Source: PseudoCAP
  3. positive regulation of oxidoreductase activity Source: PseudoCAP
  4. regulation of arginine catabolic process Source: PseudoCAP
  5. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Iron

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional activator protein anr
Gene namesi
Name:anr
Ordered Locus Names:PA1544
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002438: Chromosome

Organism-specific databases

PseudoCAPiPA1544.

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244Transcriptional activator protein anr
PRO_0000100142Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi208964.PA1544.

Structurei

3D structure databases

ProteinModelPortaliP23926.
SMRiP23926. Positions 8-230.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini159 – 23274HTH crp-type
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0664.
HOGENOMiHOG000186461.
KOiK01420.
OMAiFSANQFR.
OrthoDBiEOG6RVFWF.
PhylomeDBiP23926.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view]
PRINTSiPR00034. HTHCRP.
SMARTiSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23926-1 [UniParc]FASTAAdd to Basket

« Hide

MAETIKVRAL PQAHCKDCSL APLCLPLSLT VEDMDSLDEI VKRGRPLKKG    50
EFLFRQGDPF GSVFAVRSGA LKTFSITDAG EEQITGFHLP SELVGLSGMD 100
TETYPVSAQA LETTSVCEIP FERLDELSEQ LPQLRRQLMR LMSREIRDDQ 150
QMMLLLSKKT ADERIATFLV NLSARFRARG FSAQQFRLAM SRNEIGNYLG 200
LAVETVSRVF TRFQQNGLIS AEGKEVHILD SIELCALAGG QLEG 244
Length:244
Mass (Da):27,129
Last modified:March 1, 1992 - v1
Checksum:iA57E6C0CFB32600B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X58405 Genomic DNA. Translation: CAA41305.1.
X57736 Genomic DNA. Translation: CAA40906.1.
M98276 Genomic DNA. Translation: AAA25713.1.
AE004091 Genomic DNA. Translation: AAG04933.1.
PIRiS16307.
RefSeqiNP_250235.1. NC_002516.2.

Genome annotation databases

EnsemblBacteriaiAAG04933; AAG04933; PA1544.
GeneIDi883009.
KEGGipae:PA1544.
PATRICi19837422. VBIPseAer58763_1597.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X58405 Genomic DNA. Translation: CAA41305.1 .
X57736 Genomic DNA. Translation: CAA40906.1 .
M98276 Genomic DNA. Translation: AAA25713.1 .
AE004091 Genomic DNA. Translation: AAG04933.1 .
PIRi S16307.
RefSeqi NP_250235.1. NC_002516.2.

3D structure databases

ProteinModelPortali P23926.
SMRi P23926. Positions 8-230.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 208964.PA1544.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG04933 ; AAG04933 ; PA1544 .
GeneIDi 883009.
KEGGi pae:PA1544.
PATRICi 19837422. VBIPseAer58763_1597.

Organism-specific databases

PseudoCAPi PA1544.

Phylogenomic databases

eggNOGi COG0664.
HOGENOMi HOG000186461.
KOi K01420.
OMAi FSANQFR.
OrthoDBi EOG6RVFWF.
PhylomeDBi P23926.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProi IPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view ]
PRINTSi PR00034. HTHCRP.
SMARTi SM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view ]
SUPFAMi SSF51206. SSF51206. 1 hit.
PROSITEi PS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and molecular characterization of a transcriptional regulator from Pseudomonas aeruginosa PAO1 exhibiting structural and functional similarity to the FNR protein of Escherichia coli."
    Sawers R.G.
    Mol. Microbiol. 5:1469-1481(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
  2. "Anaerobic growth and cyanide synthesis of Pseudomonas aeruginosa depend on anr, a regulatory gene homologous with fnr of Escherichia coli."
    Zimmermann A., Reimmann C., Galimand M., Haas D.
    Mol. Microbiol. 5:1483-1490(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
  3. "RpoN-independent promoters having a conserved GG-N10-GC motif in Pseudomonas aeruginosa."
    Savioz A., Zimmermann A., Haas D.
    Submitted (JAN-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Entry informationi

Entry nameiANR_PSEAE
AccessioniPrimary (citable) accession number: P23926
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: July 9, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Possesses 4 cysteines which may bind a metal ion (possibly iron).

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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